{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T01:58:43Z","timestamp":1785463123079,"version":"3.56.0"},"reference-count":25,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2026,6,22]],"date-time":"2026-06-22T00:00:00Z","timestamp":1782086400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,6,22]],"date-time":"2026-06-22T00:00:00Z","timestamp":1782086400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100008083","name":"Xihua University","doi-asserted-by":"publisher","award":["xjjg2025100"],"award-info":[{"award-number":["xjjg2025100"]}],"id":[{"id":"10.13039\/501100008083","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["iubmb.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Biochem Molecular Bio Educ"],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Traditional microbiology experimental teaching methodology, often based on rigid \u201ccookbook\u201d experiment plans, fails to meet the growing need to cultivate skilled and innovative individuals. Course\u2010based undergraduate research experiences (CUREs) provide a solution by integrating research\u2010based learning into the curriculum, offering an opportunity to improve the \u201chard\u201d and \u201csoft\u201d skills for science, technology, engineering, and mathematics (STEM) students. In this study, a CURE was incorporated into the microbiology experiment curriculum focusing on the isolation and characterization of antimicrobial\u2010producing lactic acid bacteria (LAB) from fermented Sichuan pickles. The CURE was divided into four key sections: (i) designing an experimental plan, (ii) isolation of LAB, (iii) evaluating the antibacterial effects and antibacterial active substances of LAB, and (iv) identifying LAB species and completing the experimental report. Through a tutor observation of the experiment process and a student questionnaire survey, the study demonstrated that CURE\u2010based microbiology experiments significantly improved students' laboratory skills and microbiological\u2010related experimental operation ability and nurtured their scientific thinking. This approach enhances students' preparedness for future career success and cultivates the growth of a well\u2010rounded, skilled person in STEM disciplines.<\/jats:p>","DOI":"10.1002\/bmb.70064","type":"journal-article","created":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T03:52:38Z","timestamp":1782186758000},"page":"408-415","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["A\n                    <scp>CURE<\/scp>\n                    for Microbiology Experiment: Isolation and Characterization of Antimicrobial\u2010Producing Lactic Acid Bacteria From Fermented Sichuan Pickle Against Pathogenic Bacteria"],"prefix":"10.1002","volume":"54","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5260-2092","authenticated-orcid":false,"given":"Lijun","family":"Wang","sequence":"first","affiliation":[{"name":"School of Food and Bioengineering Xihua University  Chengdu China"},{"name":"Food Microbiology Key Laboratory of Sichuan Province  Chengdu China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhenni","family":"Yu","sequence":"additional","affiliation":[{"name":"School of Food and Bioengineering Xihua University  Chengdu China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,6,22]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1080\/00219266.2022.2147575"},{"key":"e_1_2_10_3_1","unstructured":"Y.Liu \u201cResearch on the Evaluation of University Teachers' Competency Based on the Cultivation of Innovative Talents \u201d(master's thesis Sichuan University 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