{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T01:50:42Z","timestamp":1760061042554,"version":"build-2065373602"},"reference-count":5,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2005,4,6]],"date-time":"2005-04-06T00:00:00Z","timestamp":1112745600000},"content-version":"vor","delay-in-days":4297,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Biomedical Chromatography"],"published-print":{"date-parts":[[1993,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>A high performance liquid chromatographic (HPLC) method has been developed for the determination of levomepromazine in human breast milk and serum. The levomepromazine was extracted by a rapid and simple extraction method using a Sep\u2010Pak C<jats:sub>18<\/jats:sub> cartridge. The extracts were separated by HPLC on a C<jats:sub>8<\/jats:sub> bonded reversed phase column and detected by UV absorbance at 254 nm. There was no interference with endogenous substance in human breast milk and serum. A linear relationship was obtained for the levomepromazine over the concentration range of 10\u2013300 ng\/mL. The recoveries of levomepromazine added to human breast milk and serum were 92.5\u201399.1% and 86.9\u2013103.9%, respectively.<\/jats:p>","DOI":"10.1002\/bmc.1130070411","type":"journal-article","created":{"date-parts":[[2005,5,27]],"date-time":"2005-05-27T20:33:38Z","timestamp":1117226018000},"page":"227-228","source":"Crossref","is-referenced-by-count":11,"title":["High performance liquid chromatographic determination of levomepromazine in human breast milk and serum using solid phase extraction"],"prefix":"10.1002","volume":"7","author":[{"given":"Tadashi","family":"Ohkubo","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ritsuko","family":"Shimoyama","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazunobu","family":"Sugawara","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,4,6]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9673(01)81502-8"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/00007691-199011000-00011"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0378-4347(00)80360-6"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/jps.2600810922"},{"key":"e_1_2_1_6_1","first-page":"359","volume":"103","author":"Shore M. F.","year":"1970","journal-title":"Can. Pharm. J."}],"container-title":["Biomedical Chromatography"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fbmc.1130070411","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/analyticalsciencejournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/bmc.1130070411","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T20:10:23Z","timestamp":1760040623000},"score":1,"resource":{"primary":{"URL":"https:\/\/analyticalsciencejournals.onlinelibrary.wiley.com\/doi\/10.1002\/bmc.1130070411"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1993,7]]},"references-count":5,"journal-issue":{"issue":"4","published-print":{"date-parts":[[1993,7]]}},"alternative-id":["10.1002\/bmc.1130070411"],"URL":"https:\/\/doi.org\/10.1002\/bmc.1130070411","archive":["Portico"],"relation":{},"ISSN":["0269-3879","1099-0801"],"issn-type":[{"type":"print","value":"0269-3879"},{"type":"electronic","value":"1099-0801"}],"subject":[],"published":{"date-parts":[[1993,7]]}}}