{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T14:31:23Z","timestamp":1786977083954,"version":"build-2736575974"},"reference-count":16,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2005,4,6]],"date-time":"2005-04-06T00:00:00Z","timestamp":1112745600000},"content-version":"vor","delay-in-days":3628,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Biomedical Chromatography"],"published-print":{"date-parts":[[1995,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Porphyrin metabolisms in human porphyria cutanea tarda (PCT) and in rats treated with hexachlorobenzene (HCB) have been studied in detail by high performance thin layer chromatography (HPTLC), high performance liquid chromatography (HPLC) and liquid secondary ion mass spectrometry (LSIMS). The analyses of porphyrin metabolites in the urine, faeces and liver biopsies of patients with PCT have shown that apart from uroporphyrin I and III and their expected decarboxylation intermediates and products, a complex mixture of many other porphyrins are present. The new porphyrins identified are:\n                    <jats:italic>meso<\/jats:italic>\n                    \u2010hydroxyuroporphyrin III, \u03b2\u2010hydroxypropionic acid uroporphyrin III, hydroxyacetic acid uroporphyrin III, peroxyacetic acid uroporphyrin III, \u03b2\u2010hydroxypropionic acid heptacarboxylic acid porphyrin III, hydroxyacetic acid heptacarboxylic porphyrin III and peroxyacetic acid pentacarboxylic porphyrin III.\n                  <\/jats:p>","DOI":"10.1002\/bmc.1130090302","type":"journal-article","created":{"date-parts":[[2005,5,28]],"date-time":"2005-05-28T12:38:54Z","timestamp":1117283934000},"page":"113-122","source":"Crossref","is-referenced-by-count":26,"title":["Isolation and characterization of new porphyrin metabolites in human porphyria cutanea tarda and in rats treated with hexachlorobenzene by HPTLC, HPLC and liquid secondary ion mass spectrometry"],"prefix":"10.1002","volume":"9","author":[{"given":"Jinli","family":"Luo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chang Kee","family":"Lim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2005,4,6]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1042\/bj2500161"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00295407"},{"key":"e_1_2_1_4_1","first-page":"857","volume-title":"Dermatology in five continents","author":"Elder G. H.","year":"1988"},{"key":"e_1_2_1_5_1","first-page":"71","volume":"51","author":"Elder G. H.","year":"1976","journal-title":"Clin. Sci. Mol. Med."},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM197808102990603"},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198204013061302"},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(79)90403-0"},{"key":"e_1_2_1_9_1","unstructured":"Guo R.(1992).Porphyrin Metabolism in Congenital Erythropoietic Porphyria.Ph. D. Thesis Open University UK."},{"key":"e_1_2_1_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9673(01)88566-6"},{"key":"e_1_2_1_11_1","doi-asserted-by":"publisher","DOI":"10.1042\/bj2640293"},{"key":"e_1_2_1_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/bmc.1130040404"},{"key":"e_1_2_1_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/bmc.1130050202"},{"key":"e_1_2_1_14_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI108560"},{"key":"e_1_2_1_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.0954-6820.1970.tb08003.x"},{"key":"e_1_2_1_16_1","doi-asserted-by":"publisher","DOI":"10.3109\/10408448509029323"},{"key":"e_1_2_1_17_1","first-page":"1293","volume":"11","author":"Woodward R. B.","year":"1962","journal-title":"Ind. Chim. Belg."}],"container-title":["Biomedical Chromatography"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fbmc.1130090302","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/analyticalsciencejournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/bmc.1130090302","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T19:39:46Z","timestamp":1760038786000},"score":1,"resource":{"primary":{"URL":"https:\/\/analyticalsciencejournals.onlinelibrary.wiley.com\/doi\/10.1002\/bmc.1130090302"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1995,5]]},"references-count":16,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1995,5]]}},"alternative-id":["10.1002\/bmc.1130090302"],"URL":"https:\/\/doi.org\/10.1002\/bmc.1130090302","archive":["Portico"],"relation":{},"ISSN":["0269-3879","1099-0801"],"issn-type":[{"value":"0269-3879","type":"print"},{"value":"1099-0801","type":"electronic"}],"subject":[],"published":{"date-parts":[[1995,5]]}}}