{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,26]],"date-time":"2025-10-26T21:09:48Z","timestamp":1761512988505,"version":"build-2065373602"},"reference-count":23,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2011,6,8]],"date-time":"2011-06-08T00:00:00Z","timestamp":1307491200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Biomedical Chromatography"],"published-print":{"date-parts":[[2012,2]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p>A hydrophilic interaction chromatography\u2013electrospray ionization tandem mass spectrometric method was developed for determination of anastrozole in human plasma. Anastrozole and irbesartan (internal standard) were extracted from human plasma with a mixture of dichloromethane and methyl <jats:italic>tert<\/jats:italic>\u2010butyl ether (30:70, v\/v). Analysis of the analytes was performed on a Luna HILIC column with the mobile phase of acetonitrile\u201310\u2009m <jats:sc>m<\/jats:sc> ammonium formate (95:5, v\/v) and detected by electrospray ionization tandem mass spectrometry in the selected reaction monitoring mode. The standard curve was linear (<jats:italic>r<\/jats:italic><jats:sup>2<\/jats:sup>\u2009=\u20090.9992) over the concentration range of 0.10\u201350.0\u2009ng\/mL using 200\u2009\u03bcL of plasma sample. The coefficient of variation and relative error for intra\u2010 and inter\u2010assay at four QC levels were 1.2\u201310.0% and \u22127.2\u20133.2%, respectively. The present method was applied successfully to the pharmacokinetic study of anastrozole after oral administration of 1\u2009mg anastrozole tablet to healthy male volunteers. Copyright \u00a9 2011 John Wiley &amp; Sons, Ltd.<\/jats:p>","DOI":"10.1002\/bmc.1658","type":"journal-article","created":{"date-parts":[[2011,6,8]],"date-time":"2011-06-08T05:10:03Z","timestamp":1307509803000},"page":"261-266","source":"Crossref","is-referenced-by-count":5,"title":["Hydrophilic interaction chromatography\u2013electrospray ionization tandem mass spectrometric analysis of anastrozole in human plasma and its application to a pharmacokinetic study"],"prefix":"10.1002","volume":"26","author":[{"given":"Hye Young","family":"Ji","sequence":"first","affiliation":[{"name":"Drug Metabolism and Bioanalysis Laboratory, College of Pharmacy The Catholic University of Korea  Bucheon 420\u2010743 Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ji\u2010Hong","family":"Sohn","sequence":"additional","affiliation":[{"name":"Clinical Trial Center Inje University Pusan Paik Hospital  Pusan 614\u2010735 Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hye Suk","family":"Lee","sequence":"additional","affiliation":[{"name":"Drug Metabolism and Bioanalysis Laboratory, College of Pharmacy The Catholic University of Korea  Bucheon 420\u2010743 Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2011,6,8]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpba.2008.06.006"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/bmc.1071"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00216-010-4075-z"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0378-4347(97)00129-1"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.aca.2009.01.054"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/mas.20252"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/bmc.172"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0960-0760(03)00364-9"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2002.20.3.751"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/jssc.200700451"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/bmc.1354"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/jssc.200900674"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1021\/ac902616k"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/jssc.200900148"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/rcm.2545"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1021\/ac020361s"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/rcm.2729"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jchromb.2006.11.044"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1002\/jssc.200700630"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1021\/ac102523q"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1002\/mas"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1002\/bmc.1476"},{"key":"e_1_2_7_24_1","first-page":"573","article-title":"Pharmacokinetics of anastrozole in Chinese male volunteers","volume":"22","author":"Yuan J","year":"2001","journal-title":"Acta Pharmacological Sinica"}],"container-title":["Biomedical Chromatography"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fbmc.1658","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/analyticalsciencejournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/bmc.1658","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T19:20:34Z","timestamp":1760037634000},"score":1,"resource":{"primary":{"URL":"https:\/\/analyticalsciencejournals.onlinelibrary.wiley.com\/doi\/10.1002\/bmc.1658"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,6,8]]},"references-count":23,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2012,2]]}},"alternative-id":["10.1002\/bmc.1658"],"URL":"https:\/\/doi.org\/10.1002\/bmc.1658","archive":["Portico"],"relation":{},"ISSN":["0269-3879","1099-0801"],"issn-type":[{"type":"print","value":"0269-3879"},{"type":"electronic","value":"1099-0801"}],"subject":[],"published":{"date-parts":[[2011,6,8]]}}}