{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T01:56:04Z","timestamp":1760061364026,"version":"build-2065373602"},"reference-count":8,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2002,10,11]],"date-time":"2002-10-11T00:00:00Z","timestamp":1034294400000},"content-version":"vor","delay-in-days":10,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Biomedical Chromatography"],"published-print":{"date-parts":[[2002,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>A newly developed Pirkle\u2010type straight chiral stationary phase (CSP), based on the 3,5\u2010dinitrobenzoyl derivative of 1,2 diphenylethylene\u2010diamine and known as ULMO, has been successfully applied to the direct resolution of the enantiomers of several diuretics by liquid chromatography. In this study, the effect of changes in the mobile phase and the intrinsic stereoselective properties of this CSP towards a specific racemate are determined experimentally. A mobile phase consisting of n\u2010hexane and 2\u2010propanol appears most appropriate for the chiral separation of the tested diuretics on the ULMO\u2010column. Copyright \u00a9 2002 John Wiley &amp; Sons, Ltd.<\/jats:p>","DOI":"10.1002\/bmc.179","type":"journal-article","created":{"date-parts":[[2002,10,14]],"date-time":"2002-10-14T12:39:51Z","timestamp":1034599191000},"page":"437-440","source":"Crossref","is-referenced-by-count":3,"title":["Enantiomeric separation of diuretics on a novel pirkle\u2010type chiral stationary phase"],"prefix":"10.1002","volume":"16","author":[{"given":"Ann","family":"Vercauteren","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guido Van der","family":"Weken","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tineke","family":"Vankeirsbilck","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hassan Y.","family":"Aboul\u2010Enein","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Willy R. G.","family":"Baeyens","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2002,10,11]]},"reference":[{"volume-title":"Chiral Separations: Applications and Technology","year":"1997","author":"Ahuja S","key":"e_1_2_1_2_1"},{"volume-title":"Chiral Separations by Chromatography","year":"2000","author":"Ahuja S","key":"e_1_2_1_3_1"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1080\/10826079508009263"},{"key":"e_1_2_1_5_1","first-page":"115","volume-title":"A Practical Approach to Chiral Separations by Liquid Chromatography","author":"Dingenen J","year":"1994"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9673(00)00157-6"},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02687754"},{"key":"e_1_2_1_8_1","first-page":"336","volume-title":"Chiral Separations by HPLC. Applications to Pharmaceutical Compounds","author":"Shibata T","year":"1993"},{"key":"e_1_2_1_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02292974"}],"container-title":["Biomedical Chromatography"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fbmc.179","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/analyticalsciencejournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/bmc.179","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T00:35:43Z","timestamp":1760056543000},"score":1,"resource":{"primary":{"URL":"https:\/\/analyticalsciencejournals.onlinelibrary.wiley.com\/doi\/10.1002\/bmc.179"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2002,10]]},"references-count":8,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2002,10]]}},"alternative-id":["10.1002\/bmc.179"],"URL":"https:\/\/doi.org\/10.1002\/bmc.179","archive":["Portico"],"relation":{},"ISSN":["0269-3879","1099-0801"],"issn-type":[{"type":"print","value":"0269-3879"},{"type":"electronic","value":"1099-0801"}],"subject":[],"published":{"date-parts":[[2002,10]]}}}