{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T19:05:18Z","timestamp":1792782318827,"version":"4.5.0"},"reference-count":34,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2015,3,25]],"date-time":"2015-03-25T00:00:00Z","timestamp":1427241600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"crossref","award":["21275098"],"award-info":[{"award-number":["21275098"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Innovation Funds of Graduate Programs of Shaanxi Normal University","award":["2013CXS048"],"award-info":[{"award-number":["2013CXS048"]}],"id":[{"id":"https:\/\/ror.org\/0170z8493","id-type":"ROR","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Biomedical Chromatography"],"published-print":{"date-parts":[[2015,10]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    The banned addition of psychiatric drugs such as phenothiazines to animal feed and foodstuffs increases the risk of human organ lesion. Phenothiazines usually exhibit weak native fluorescence and can be oxidized to strongly fluorescent compounds. In this study, a novel, sensitive and convenient method of HPLC\u2010fluorescence detection based on post\u2010column on\u2010line oxidizing with lead dioxide solid\u2010phase reactor has been developed for simultaneous determination of three banned psychotropic drugs, promethazine, chlorpromazine and thioridazine. Three compounds were successfully separated on an Agilent TC\u2010C\n                    <jats:sub>18<\/jats:sub>\n                    column with mobile phase of acetonitrile (A) and water (B), both containing 0.5% (v\/v) formic acid. A gradient elution was programmed and fluorimetric detection was performed at\n                    <jats:italic>\u03bb<\/jats:italic>\n                    <jats:sub>ex<\/jats:sub>\n                    \/\n                    <jats:italic>\u03bb<\/jats:italic>\n                    <jats:sub>em<\/jats:sub>\n                    of 332\/373 nm for promethazine, 340\/380 nm for chlorpromazine and 352\/432 nm for thioridazine. The calibration graphs gave good linearity over the concentration ranges of 30.0\u20134976.4 \u00b5g\/L for promethazine, 2.0\u20132153.2 \u00b5g\/L for chlorpromazine, and 15.0\u20133088.0 \u00b5g\/L for thioridazine, and correlation coefficients (\n                    <jats:italic>r<\/jats:italic>\n                    ) were \u22650.995. The method was applied to the determination of phenothiazines in pig feed and pig tissue, and the average spiked recoveries were in the range 69.1\u2013115.4%. Copyright \u00a9 2015 John Wiley &amp; Sons, Ltd.\n                  <\/jats:p>","DOI":"10.1002\/bmc.3455","type":"journal-article","created":{"date-parts":[[2015,3,25]],"date-time":"2015-03-25T03:58:50Z","timestamp":1427255930000},"page":"1535-1540","source":"Crossref","is-referenced-by-count":12,"title":["Simultaneous determination of three banned psychiatric drugs in pig feed and tissue using solid\u2010phase reactor on\u2010line oxidizing and HPLC\u2010fluorescence detection"],"prefix":"10.1002","volume":"29","author":[{"given":"Liang","family":"Qi","sequence":"first","affiliation":[{"name":"Key Laboratory of Analytical Chemistry for Life Science of Shaanxi Province, School of Chemistry and Chemical Engineering Shaanxi Normal University  Xi'an 710062 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li\u2010Min","family":"Duan","sequence":"additional","affiliation":[{"name":"Key Laboratory of Analytical Chemistry for Life Science of Shaanxi Province, School of Chemistry and Chemical Engineering Shaanxi Normal University  Xi'an 710062 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiao\u2010Huan","family":"Sun","sequence":"additional","affiliation":[{"name":"Key Laboratory of Analytical Chemistry for Life Science of Shaanxi Province, School of Chemistry and Chemical Engineering Shaanxi Normal University  Xi'an 710062 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Zhang","sequence":"additional","affiliation":[{"name":"Key Laboratory of Analytical Chemistry for Life Science of Shaanxi Province, School of Chemistry and Chemical Engineering Shaanxi Normal University  Xi'an 710062 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhi\u2010Qi","family":"Zhang","sequence":"additional","affiliation":[{"name":"Key Laboratory of Analytical Chemistry for Life Science of Shaanxi Province, School of Chemistry and Chemical Engineering Shaanxi Normal University  Xi'an 710062 China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2015,3,25]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1080\/00032710008543035"},{"key":"e_1_2_6_3_1","first-page":"463","article-title":"Determination of phenothiazine derivatives under a cerometric method. I. Assay of chloroperazine, diethazine maleate, and thioridazine hydrochloride","volume":"29","author":"Basinska H","year":"1972","journal-title":"Acta Polonica Pharmaceutica"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.talanta.2010.11.031"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.talanta.2005.11.001"},{"key":"e_1_2_6_6_1","volume-title":"Guide to Veterinary Drugs","author":"Commission of Chinese Veterinary Phamacopoeia","year":"2005"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpba.2004.10.048"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1021\/ac0492315"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.chroma.2010.02.047"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1021\/ac0346050"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.talanta.2007.09.018"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/0039-9140(84)80280-5"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0039-9140(98)00014-9"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0731-7085(99)00270-8"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.chroma.2005.06.039"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.talanta.2004.03.008"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.talanta.2008.10.049"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpba.2005.03.024"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.chroma.2007.03.079"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.talanta.2004.09.008"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1021\/ac030162o"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1021\/ac040095d"},{"key":"e_1_2_6_23_1","first-page":"677","article-title":"Determination of chlorpromazine and promethazine and their metabolites in animal food using ultra performance liquid chromatography with tandem mass spectrometry","volume":"28","author":"Qi SL","year":"2009","journal-title":"Journal of Instrumental Analysis"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.1039\/a906623c"},{"key":"e_1_2_6_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/0039-9140(96)01861-9"},{"key":"e_1_2_6_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpba.2004.05.003"},{"key":"e_1_2_6_27_1","unstructured":"The Ministry of Agriculture.Bulletin of the People's Republic of China2002; 235."},{"key":"e_1_2_6_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/0039-9140(88)80095-X"},{"key":"e_1_2_6_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0378-4347(98)00485-X"},{"key":"e_1_2_6_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.talanta.2006.02.052"},{"key":"e_1_2_6_31_1","doi-asserted-by":"publisher","DOI":"10.1021\/ac50003a015"},{"key":"e_1_2_6_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.talanta.2012.06.052"},{"key":"e_1_2_6_33_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00216-004-2961-y"},{"key":"e_1_2_6_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.talanta.2006.09.016"},{"key":"e_1_2_6_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.talanta.2008.04.032"}],"container-title":["Biomedical Chromatography"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fbmc.3455","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/analyticalsciencejournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/bmc.3455","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T19:55:52Z","timestamp":1760039752000},"score":1,"resource":{"primary":{"URL":"https:\/\/analyticalsciencejournals.onlinelibrary.wiley.com\/doi\/10.1002\/bmc.3455"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,3,25]]},"references-count":34,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2015,10]]}},"alternative-id":["10.1002\/bmc.3455"],"URL":"https:\/\/doi.org\/10.1002\/bmc.3455","archive":["Portico"],"relation":{},"ISSN":["0269-3879","1099-0801"],"issn-type":[{"value":"0269-3879","type":"print"},{"value":"1099-0801","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,3,25]]}}}