{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T14:40:06Z","timestamp":1782830406268,"version":"3.54.5"},"reference-count":39,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2019,2,19]],"date-time":"2019-02-19T00:00:00Z","timestamp":1550534400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["analyticalsciencejournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Biomedical Chromatography"],"published-print":{"date-parts":[[2019,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The present study was carried out to determine 16 antibiotics belonging to seven different groups (tetracyclines, sulfonamides, penicillins, fluoroquinolones, macrolides, lincosamides and trimethoprims) in duck meat. A solid\u2010phase extraction method based on Oasis HLB cartridges coupled with liquid chromatography\u2013electrospray ionization tandem mass spectrometry was developed. Solutions of 0.1\u00a0<jats:sc>m<\/jats:sc> ethylenediaminetetraacetic acid disodium salt and 2% trifluoroacetic acid were used for the preliminary extraction of the target antibiotics from duck meat and <jats:italic>n<\/jats:italic>\u2010hexane was used for purification prior to solid\u2010phase extraction. Mobile phases composed of 0.1% trifluoroacetic acid in distilled water (solvent A) and 0.1% trifluoroacetic acid in methanol (solvent B), combined with a reversed\u2010phase C<jats:sub>18<\/jats:sub> analytical column, provided the optimal separation and signal intensity. The linearity of the method was assessed using six concentrations (5, 10, 20, 30, 40, and 50\u2009\u03bcg\/kg), and the recoveries, which were calculated at three spiking concentrations (5, 10 and 20\u2009\u03bcg\/kg), were in the range 69.8\u2013103.3% with relative standard deviations (RSDs) \u2264\u20096.9% for the 16 tested antibiotics. Matrix effects ranging from \u221247.2 to \u221213.5% were observed for all the analytes, and the limits of quantitation (LOQ), which ranged from 4.93 to 26.21\u2009\u03bcg\/kg, were much lower than the maximum residue limits (MRLs) set by various regulatory authorities. Ten samples from a market were tested, and none of the target analytes were detected. Thus, a simple and versatile protocol has been developed to detect and quantify 16 antibiotics in duck meat samples.<\/jats:p>","DOI":"10.1002\/bmc.4501","type":"journal-article","created":{"date-parts":[[2019,1,31]],"date-time":"2019-01-31T07:19:05Z","timestamp":1548919145000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":20,"title":["Development and validation of a solid\u2010phase extraction method coupled with LC\u2013MS\/MS for the simultaneous determination of 16 antibiotic residues in duck meat"],"prefix":"10.1002","volume":"33","author":[{"given":"Weijia","family":"Zheng","sequence":"first","affiliation":[{"name":"Department of Veterinary Pharmacology and Toxicology, College of Veterinary Medicine Konkuk University  Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6596-7907","authenticated-orcid":false,"given":"A. M.","family":"Abd El\u2010Aty","sequence":"additional","affiliation":[{"name":"Department of Pharmacology, Faculty of Veterinary Medicine Cairo University  Giza Egypt"},{"name":"Department of Medical Pharmacology, Medical Faculty Ataturk University  Erzurum Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seong\u2010Kwan","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Veterinary Pharmacology and Toxicology, College of Veterinary Medicine Konkuk University  Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeong\u2010Min","family":"Choi","sequence":"additional","affiliation":[{"name":"Department of Veterinary Pharmacology and Toxicology, College of Veterinary Medicine Konkuk University  Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Da\u2010Hee","family":"Park","sequence":"additional","affiliation":[{"name":"Department of Veterinary Pharmacology and Toxicology, College of Veterinary Medicine Konkuk University  Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kyung\u2010Hee","family":"Yoo","sequence":"additional","affiliation":[{"name":"Department of Veterinary Pharmacology and Toxicology, College of Veterinary Medicine Konkuk University  Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Young\u2010Sun","family":"Kang","sequence":"additional","affiliation":[{"name":"Department of Veterinary Pharmacology and Toxicology, College of Veterinary Medicine Konkuk University  Seoul Republic of Korea"},{"name":"Department of Biomedical Science and Technology Konkuk University  Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jong\u2010Sup","family":"Jeon","sequence":"additional","affiliation":[{"name":"Public Health Research Division Gyeonggi Province Institute of Health and Environment  Jangan\u2010gu, Suwon\u2010Si Gyeonggi\u2010do Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmet","family":"Hac\u0131m\u00fcft\u00fco\u011flu","sequence":"additional","affiliation":[{"name":"Department of Medical Pharmacology, Medical Faculty Ataturk University  Erzurum Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5361-2903","authenticated-orcid":false,"given":"Jae\u2010Han","family":"Shim","sequence":"additional","affiliation":[{"name":"Natural Products Chemistry Laboratory, College of Agriculture and Life Sciences Chonnam National University  Gwangju Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5500-3901","authenticated-orcid":false,"given":"Ho\u2010Chul","family":"Shin","sequence":"additional","affiliation":[{"name":"Department of Veterinary Pharmacology and Toxicology, College of Veterinary Medicine Konkuk University  Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,2,19]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1017\/S000711451400124X"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodres.2011.02.051"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.trac.2007.08.001"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00216-012-5868-z"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.chroma.2008.09.011"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.chroma.2008.03.057"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.aca.2010.01.001"},{"key":"e_1_2_6_9_1","unstructured":"Codex Alimentarius Commission(2014). 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