{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T03:04:17Z","timestamp":1777518257501,"version":"3.51.4"},"reference-count":38,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2022,3,22]],"date-time":"2022-03-22T00:00:00Z","timestamp":1647907200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["analyticalsciencejournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Biomedical Chromatography"],"published-print":{"date-parts":[[2022,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:italic>Iris<\/jats:italic> genus plants are a valuable source of bioactive compounds, which are an important component for pharmaceutical development. The present article shows the potential for mineral nutrition with application of magnesium sulfate, iron chelates and potassium oxide affecting the phenolic compound contents in <jats:italic>Iris hybrida<\/jats:italic> \u2018Tsikavynka\u2019, <jats:italic>I. hybrida<\/jats:italic> \u2018Tambo\u2019 and <jats:italic>I. hybrid\u0430<\/jats:italic> \u2018Widecombe Fire\u2019. The effect of mineral processing was specific to plant organs and varied in the component composition. The <jats:italic>Iris<\/jats:italic> rhizomes had an increased total phenolic compound content after treatment (up to 10% of the total isoflavonoid content, up to 8% of phenolic acids, up to 5% of <jats:italic>\u03b3<\/jats:italic>\u2010pyrones and up to 13% of flavonoids), determined using UV\u2013vis spectroscopy. A positive effect of nutrition on the biosynthesis and content of individual isoflavonoids (tectoridin, nigricin <jats:sc>d<\/jats:sc>\u2010glucoside, genistin, iristectorigenin B, nigricin, irigenin and irisolidone) and xanthone mangiferin in <jats:italic>Iris<\/jats:italic> rhizomes by HPLC was established. In addition, an increase in the chlorogenic acid amount in <jats:italic>Iris<\/jats:italic> leaves was noted. The results demonstrate the sensitivity of <jats:italic>Iris<\/jats:italic> phenylpropanoid metabolism to mineral nutrition and can be used to predict medical plant cultivation with increased content of bioactive constituents.<\/jats:p>","DOI":"10.1002\/bmc.5369","type":"journal-article","created":{"date-parts":[[2022,3,14]],"date-time":"2022-03-14T06:14:07Z","timestamp":1647238447000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Bioactive constituents of <i>Iris hybrida<\/i> (Iridaceae): Processing effect"],"prefix":"10.1002","volume":"36","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3822-8409","authenticated-orcid":false,"given":"Olha","family":"\u041cykhailenko","sequence":"first","affiliation":[{"name":"Department of Pharmaceutical Chemistry National University of Pharmacy of the Ministry of Health of Ukraine  Kharkiv Ukraine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sergiy","family":"Chetvernya","sequence":"additional","affiliation":[{"name":"M.M. Hryshko National Botanical Garden of the National Academy of Sciences of Ukraine  Kyiv Ukraine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1212-1649","authenticated-orcid":false,"given":"Ivan","family":"Bezruk","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical Chemistry National University of Pharmacy of the Ministry of Health of Ukraine  Kharkiv Ukraine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yrii","family":"Buydin","sequence":"additional","affiliation":[{"name":"M.M. Hryshko National Botanical Garden of the National Academy of Sciences of Ukraine  Kyiv Ukraine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nadija","family":"Dhurenko","sequence":"additional","affiliation":[{"name":"M.M. 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