{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T01:47:54Z","timestamp":1760060874379,"version":"build-2065373602"},"reference-count":28,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2023,5,6]],"date-time":"2023-05-06T00:00:00Z","timestamp":1683331200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["analyticalsciencejournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Biomedical Chromatography"],"published-print":{"date-parts":[[2023,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Fungicides have their own unique characteristics and modes of action; a combination formulation [combination product (combi product)] of trifloxystrobin and propineb was applied to tomatoes for their dissipation kinetics and to ensure consumer safety. The combi product was applied at a 10\u2010day interval with standard (61.25\u2009+\u20091072.75\u2009g a.i. ha<jats:sup>\u22121<\/jats:sup>) and double (122.5\u2009+\u20092145.50\u2009g a.i. ha<jats:sup>\u22121<\/jats:sup>) doses. The efficient analytical method was established using the quick, easy, cheap, effective, rugged, and safe (QuEChERS) approach followed by LC\u2013MS. The maximum residue levels of 0.15 and 0.35\u2009mg\u2009kg<jats:sup>\u22121<\/jats:sup> of trifloxystrobin were detected in tomato fruits immediately after application at standard and double doses, respectively. The corresponding levels of propineb as carbon disulfide were 0.47 and 0.90\u2009mg\u2009kg<jats:sup>\u22121<\/jats:sup>, respectively. Considering trifloxystrobin (0.7\u2009mg\u2009kg<jats:sup>\u22121<\/jats:sup>) codex maximum residue limit and propineb as dithiocarbamate (3.0\u2009mg\u2009kg<jats:sup>\u22121<\/jats:sup>) European Commission maximum residue limit in tomato, a pre\u2010harvest interval of 1\u2009day can be proposed. The anticipated residue contributions of both fungicides were far less than the acceptable daily intake. The targeted hazard quotient and hazard index were also less than 1 for both fungicides. Furthermore, the theoretical maximum residue contribution was less than its maximum permissible intake, which indicates that the consumption of tomatoes containing the measured value of each fungicide residue could not pose any health risks.<\/jats:p>","DOI":"10.1002\/bmc.5660","type":"journal-article","created":{"date-parts":[[2023,4,21]],"date-time":"2023-04-21T23:45:35Z","timestamp":1682120735000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Behavior of trifloxystrobin and propineb as combination product in tomato (<scp><i>Solanum lycopersicum<\/i><\/scp>) and their risk assessment for human health"],"prefix":"10.1002","volume":"37","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6852-3823","authenticated-orcid":false,"given":"Nitesh S.","family":"Litoriya","sequence":"first","affiliation":[{"name":"All India Network Project on Pesticide Residues, ICAR Unit\u20109 Anand Agricultural University  Anand Gujarat India"},{"name":"Main Forage Research Station Anand Agricultural University  Anand Gujarat India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jignesh H.","family":"Patel","sequence":"additional","affiliation":[{"name":"All India Network Project on Pesticide Residues, ICAR Unit\u20109 Anand Agricultural University  Anand Gujarat India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pritesh M.","family":"Thakor","sequence":"additional","affiliation":[{"name":"All India Network Project on Pesticide Residues, ICAR Unit\u20109 Anand Agricultural University  Anand Gujarat India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nirmalsinh R.","family":"Chauhan","sequence":"additional","affiliation":[{"name":"All India Network Project on Pesticide Residues, ICAR Unit\u20109 Anand Agricultural University  Anand Gujarat India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Suchi","family":"Chawla","sequence":"additional","affiliation":[{"name":"All India Network Project on Pesticide Residues, ICAR Unit\u20109 Anand Agricultural University  Anand Gujarat India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paresh G.","family":"Shah","sequence":"additional","affiliation":[{"name":"All India Network Project on Pesticide Residues, ICAR Unit\u20109 Anand Agricultural University  Anand Gujarat India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,5,6]]},"reference":[{"issue":"5","key":"e_1_2_8_2_1","first-page":"389","article-title":"Degradation dynamics and dissipation kinetics of a dithiocarbamate fungicide (Propineb) in tomato under East\u2010Indian climatic condition","volume":"8","author":"Aktar M. W.","year":"2009","journal-title":"Electronic Journal of Environmental, Agricultural and Food Chemistry"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00128-011-0362-4"},{"key":"e_1_2_8_4_1","unstructured":"AOAC Official Method 2007.01. (2007).Pesticide residues in foods by acetonitrile extraction and partitioning with magnesium sulfate.https:\/\/nucleus.iaea.org\/sites\/fcris\/Shared%20Documents\/SOP\/AOAC_2007_01.pdf"},{"issue":"1","key":"e_1_2_8_5_1","first-page":"5","article-title":"Persistence and degradation of propineb in rice (Oryza sativa L.)","volume":"24","author":"Birendrajit C.","year":"2012","journal-title":"Pesticide Research Journal"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1155\/2018\/3269065"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13762-018-2069-0"},{"key":"e_1_2_8_8_1","unstructured":"Codex Alimentarius Commission. (2006).Pesticides Database Search.https:\/\/www.fao.org\/fao-who-codexalimentarius\/codex-texts\/dbs\/pestres\/pesticide-detail\/en\/?p_id=213. Accessed on 01 June 2022."},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph8051402"},{"key":"e_1_2_8_10_1","unstructured":"European Commission. (2016).Pesticide residue(s) and maximum residue levels (mg\/kg).https:\/\/ec.europa.eu\/food\/plant\/pesticides\/eu-pesticides-database\/start\/screen\/mrls\/details?lg_code=EN&pest_res_id_list=83&product_id_list=. Accessed on 01 June 2022."},{"key":"e_1_2_8_11_1","unstructured":"FAOSTAT. (2001).Agricultural Organization of the United Nations Statistical Database."},{"volume-title":"Monthly Report Tomato. April, 2020","year":"2020","author":"Horticulture Statistics Division","key":"e_1_2_8_12_1"},{"key":"e_1_2_8_13_1","first-page":"163","article-title":"Mathematical treatment of loss of pesticide residues","volume":"9","author":"Hoskins W. 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