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Danggui (<jats:italic>Angelica sinensis<\/jats:italic> Radix)\u2013Yimucao (<jats:italic>Leonuri<\/jats:italic> Herba), as a herbal pair (DY) in clinical prescriptions of traditional Chinese medicine, is often used in the treatment of gynecological diseases and has the traditional functions of tonifying the blood, promoting blood circulation, removing blood stasis and regulating menstruation. In this study, serum lipidomics were adopted to dissect the mechanism of DY in promoting recovery after medical abortion. A total of 152 differential metabolites were screened by lipidomics. All metabolites were imported into MetaboAnalyst for analysis, and finally key metabolic pathways such as glycerophospholipid metabolism, linoleic acid metabolism and pentose and glucuronate interconversions were enriched. Our results indicated that metabolic disorders in abortion mice were alleviated by DY through glycerophospholipid metabolism, while prostaglandin and leukotriene metabolites might be the key targets of DY to promote post\u2010abortion recovery.<\/jats:p>","DOI":"10.1002\/bmc.5717","type":"journal-article","created":{"date-parts":[[2023,8,15]],"date-time":"2023-08-15T02:55:50Z","timestamp":1692068150000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["The serum lipidomics reveal the action mechanism of Danggui\u2013Yimucao herbal pair in abortion mice"],"prefix":"10.1002","volume":"37","author":[{"given":"Feng\u2010Yun","family":"Bai","sequence":"first","affiliation":[{"name":"Shaanxi Eastantai Pharmaceutical Co. 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