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J.I.M.Melo, as detailed in\n                    <jats:italic>Kew Bull<\/jats:italic>\n                    . 77: 970 (2022). Antioxidant assays revealed strong radical scavenging activity (DPPH: 0.14\u2009\u00b1\u20090.02\u2009\u03bcg\/mL) and moderate iron chelation capacity (4.23\u2009\u00b1\u20090.99\u2009mg\/mL). The extract exhibited high phenolic (393.79\u2009\u00b1\u200930.14\u2009\u03bcg\/mL) and flavonoid (50.76\u2009\u00b1\u20091.40\u2009\u03bcg\/mL) contents. Enzymatic antioxidant assays showed notable activities: MDA (0.2141\u2009\u00b1\u20090.0047\u2009\u03bcM), CAT (426\u2009\u00b1\u200914.73\u2009U\/mg), PO (8.366\u2009\u00b1\u20090.15\u2009U\/mg), SOD (53.13\u2009\u00b1\u20091.41\u2009U\/mg), and Mn\u2010SOD (7.63\u2009\u00b1\u20090.31\u2009U\/mg). GC\u2013MS analysis identified major compounds including pyrrolidine (15.08%), neophytadiene (9.40%), 9,12,15\u2010octadecatrienoic acid (9.75%), and 2\u2010pentadecanone, 6,10,14\u2010trimethyl\u2010 (7.19%). Molecular docking revealed binding energies ranging from \u22123.4 to \u22125.2\u2009kcal\/mol, with 1,2\u2010cyclohexanedimethanol showing the strongest interaction. These results demonstrate the plant's significant antioxidant potential and suggest that its bioactive constituents may serve as promising candidates for pharmacological development.\n                  <\/jats:p>","DOI":"10.1002\/bmc.70147","type":"journal-article","created":{"date-parts":[[2025,6,16]],"date-time":"2025-06-16T09:42:04Z","timestamp":1750066924000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Phytochemical Analysis, Radical Scavenging Activity, and Molecular Docking Studies of\n                    <i>Heliotropium sibiricum<\/i>\n                    (L.) J.I.M.Melo"],"prefix":"10.1002","volume":"39","author":[{"given":"Alper","family":"Durmaz","sequence":"first","affiliation":[{"name":"Ali Nihat G\u00f6kyi\u011fit Botanical Garden Application and Research Center Artvin \u00c7oruh University  Artvin T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6045-0183","authenticated-orcid":false,"given":"Erdi\u00a0Can","family":"Aytar","sequence":"additional","affiliation":[{"name":"Faculty of Agriculture, Department of Horticulture U\u015fak University  U\u015fak T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9092-1350","authenticated-orcid":false,"given":"Bet\u00fcl","family":"Ayd\u0131n","sequence":"additional","affiliation":[{"name":"Faculty of Science, Department of Biology Gazi University  Ankara T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4641-0067","authenticated-orcid":false,"given":"Emine\u00a0\u0130ncilay","family":"Toruno\u011flu","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Department of Medical Biochemistry Necmettin Erbakan University  Konya T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fatma\u00a0G\u00f6n\u00fcl","family":"Solmaz","sequence":"additional","affiliation":[{"name":"Faculty of Science, Department of Biology Ondokuz May\u0131s University  Samsun T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0571-4219","authenticated-orcid":false,"given":"Altevir\u00a0Rossato","family":"Viana","sequence":"additional","affiliation":[{"name":"Department of Biochemistry and Molecular Biology Federal University of Santa Maria  Santa Maria Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ay\u015fen\u00a0Melda","family":"\u00c7olak","sequence":"additional","affiliation":[{"name":"Faculty of Agriculture, Department of Horticulture U\u015fak University  U\u015fak T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erico\u00a0Marlon\u00a0Moraes","family":"Flores","sequence":"additional","affiliation":[{"name":"Department of Chemistry Federal University of Santa Maria  Santa Maria Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,6,16]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598\u2010024\u201066491\u20102"},{"issue":"1","key":"e_1_2_7_3_1","first-page":"636","article-title":"Theoretical and Biochemical Information Studies on Compounds Detected in GCMS of Ethanol Extract of Chromolaena odorata Leaf","volume":"6","author":"Aikoye A. 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