{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,15]],"date-time":"2026-04-15T14:17:52Z","timestamp":1776262672310,"version":"3.50.1"},"reference-count":30,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2026,3,31]],"date-time":"2026-03-31T00:00:00Z","timestamp":1774915200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,3,31]],"date-time":"2026-03-31T00:00:00Z","timestamp":1774915200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["analyticalsciencejournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Biomedical Chromatography"],"published-print":{"date-parts":[[2026,5]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    This study analyzed the essential oils of Amomi Fructus Rotundus (from the whole fruit, pericarp, and non\u2010moldy\/moldy kernels) by GC\u2013MS. Thirty\u2010two compounds were identified, primarily eucalyptol, \u03b2\u2010pinene, D\u2010limonene, and \u03b1\u2010pinene. The pericarp oil showed the strongest antibacterial activity, which was linked to specific compounds (e.g., 3\u2010carene). Moldy kernels exhibited new compounds, indicating metabolic changes. Network pharmacology and molecular docking suggested anti\u2010gastritis effects via targets (e.g., EGFR, PTGS2) and inflammation\u2010related pathways. Additionally, in\u00a0vitro assays confirmed antibacterial effects against\n                    <jats:styled-content style=\"fixed-case\">\n                      <jats:italic>Escherichia coli<\/jats:italic>\n                    <\/jats:styled-content>\n                    ,\n                    <jats:styled-content style=\"fixed-case\">\n                      <jats:italic>Staphylococcus aureus<\/jats:italic>\n                    <\/jats:styled-content>\n                    ,\n                    <jats:styled-content style=\"fixed-case\">\n                      <jats:italic>Candida albicans<\/jats:italic>\n                    <\/jats:styled-content>\n                    , and\n                    <jats:styled-content style=\"fixed-case\">\n                      <jats:italic>Listeria monocytogenes<\/jats:italic>\n                    <\/jats:styled-content>\n                    . This work elucidates the oil's anti\u2010gastritis potential and antibacterial activity, supporting quality control and medicinal development.\n                  <\/jats:p>","DOI":"10.1002\/bmc.70436","type":"journal-article","created":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T06:36:54Z","timestamp":1775025414000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Chemical Composition Analysis of Amomi Fructus Rotundus Essential Oil at Different States by GC\u2013MS and Its Anti\u2010Gastritis Mechanism and Antibacterial Activity Based on Network Pharmacology and Molecular Docking"],"prefix":"10.1002","volume":"40","author":[{"given":"Zishuai","family":"Wen","sequence":"first","affiliation":[{"name":"College of Pharmacy Guangxi University of Chinese Medicine  Nanning Guangxi China"},{"name":"Preparation Room Beihai hospital of Chinese Medicine  Beihai Guangxi 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