{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T17:33:45Z","timestamp":1791999225978,"version":"4.4.0"},"reference-count":26,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2026,4,19]],"date-time":"2026-04-19T00:00:00Z","timestamp":1776556800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,4,19]],"date-time":"2026-04-19T00:00:00Z","timestamp":1776556800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["analyticalsciencejournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Biomedical Chromatography"],"published-print":{"date-parts":[[2026,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    Smilax glabra Roxb. (SGR) is the dried rhizome of\n                    <jats:italic>Smilax glabra<\/jats:italic>\n                    Roxb., a member of the Liliaceae family. As evidenced by ancient Chinese medical texts, the efficacy of this substance in the elimination of toxins, the eradication of dampness, and the promotion of joint mobility has been well documented. Modern pharmacological studies indicate that it possesses activities such as lowering uric acid, treating gouty arthritis, addressing immune system disorders, and exhibiting antitumor effects. In this paper, chemometric methods were used to construct the spectral effect relationship between the fingerprints of 15 batches of SGR extracts from different origins and varied in\u00a0vitro antigouty arthritis activities. The results showed that the chemical composition of the samples from different sources varied significantly, with the samples from Guangxi, Hunan, and Yunnan provinces exhibiting comparatively higher quality. Among the nine common peaks, neoisoastilbin and isoastilbin were considered to be significantly correlated with the antigouty arthritis activity of SGR. The results of this study will offer reference guidelines for the quality control of SGR, thereby providing a scientific basis for its pharmacodynamic foundation and quality assurance.\n                  <\/jats:p>","DOI":"10.1002\/bmc.70448","type":"journal-article","created":{"date-parts":[[2026,4,20]],"date-time":"2026-04-20T01:32:17Z","timestamp":1776648737000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Spectrum\u2010Effect Relationship Between HPLC Fingerprints and Antigouty Arthritis of Smilax Glabra Roxb"],"prefix":"10.1002","volume":"40","author":[{"given":"Danhong","family":"Zhong","sequence":"first","affiliation":[{"name":"School of Traditional Chinese Medicine Guangdong Pharmaceutical University  Guangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yiliang","family":"Li","sequence":"additional","affiliation":[{"name":"Guangdong Prov Key Lab Silviculture Protect &amp; Uti  Guangzhou Guangdong China"},{"name":"Guangdong Acad Forestry  Guangzhou Guangdong China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying","family":"Feng","sequence":"additional","affiliation":[{"name":"Forest Resources Conservat Ctr Guang Dong Prov  Guangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haidi","family":"Wang","sequence":"additional","affiliation":[{"name":"School of Traditional Chinese Medicine Guangdong Pharmaceutical University  Guangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Siqi","family":"Zheng","sequence":"additional","affiliation":[{"name":"School of Traditional Chinese Medicine Guangdong Pharmaceutical University  Guangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0161-2458","authenticated-orcid":false,"given":"Xiaoming","family":"Sun","sequence":"additional","affiliation":[{"name":"School of Traditional Chinese Medicine Guangdong Pharmaceutical University  Guangzhou China"},{"name":"Key Laboratory of State Administration of Traditional Chinese Medicine for Production &amp; Development of Cantonese Medicinal Materials  Guangzhou China"},{"name":"Comprehensive Experimental Station of Guangzhou, Chinese Material Medica China Agriculture Research System (CARS\u201021\u201016)  Guangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"family":"YuanYuan","sequence":"additional","affiliation":[{"name":"School of Traditional Chinese Medicine Guangdong Pharmaceutical University  Guangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuxin","family":"Pang","sequence":"additional","affiliation":[{"name":"Guizhou University of Chinese Medicine  China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaomin","family":"Tang","sequence":"additional","affiliation":[{"name":"School of Traditional Chinese Medicine Guangdong Pharmaceutical University  Guangzhou China"},{"name":"Key Laboratory of State Administration of Traditional Chinese Medicine for Production &amp; Development of Cantonese Medicinal Materials  Guangzhou China"},{"name":"Comprehensive Experimental Station of Guangzhou, Chinese Material Medica China Agriculture Research System (CARS\u201021\u201016)  Guangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,4,19]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jchromb.2020.121970"},{"key":"e_1_2_11_3_1","volume-title":"Pharmacopoeia of the People's Republic of China","author":"Chinese Pharmacopoeia Commission","year":"2025"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.3390\/metabo15040281"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.3390\/ph15111351"},{"issue":"12","key":"e_1_2_11_6_1","first-page":"3416","article-title":"Application of Chemometrics Methods in Quality Markers of Traditional Chinese Medicines","volume":"43","author":"Jiu X.","year":"2021","journal-title":"Chinese Patent Medicine"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.3390\/molecules25133006"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.phymed.2024.155754"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jep.2024.118817"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.3389\/FIMMU.2022.955806"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.3390\/plants11020218"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.22038\/ijbms.2020.46658.10763"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12010\u2010024\u201004930\u20106"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.11817\/j.issn.1672\u20107347.2020.190566"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.3892\/mmr.2020.11035"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.carbpol.2016.09.033"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2018.12.050"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jchromb.2024.124351"},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.1155\/2022\/1429074"},{"key":"e_1_2_11_20_1","doi-asserted-by":"publisher","DOI":"10.3390\/molecules27113477"},{"key":"e_1_2_11_21_1","doi-asserted-by":"publisher","DOI":"10.1002\/sscp.70067"},{"key":"e_1_2_11_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ctim.2011.09.004"},{"key":"e_1_2_11_23_1","doi-asserted-by":"publisher","DOI":"10.3390\/molecules25225295"},{"key":"e_1_2_11_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jep.2012.01.048"},{"key":"e_1_2_11_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpba.2018.04.005"},{"key":"e_1_2_11_26_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11655\u2010016\u20102741\u20105"},{"key":"e_1_2_11_27_1","doi-asserted-by":"publisher","DOI":"10.3390\/molecules27175698"}],"container-title":["Biomedical Chromatography"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/analyticalsciencejournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/bmc.70448","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/analyticalsciencejournals.onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/bmc.70448","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/analyticalsciencejournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/bmc.70448","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T04:50:51Z","timestamp":1778820651000},"score":1,"resource":{"primary":{"URL":"https:\/\/analyticalsciencejournals.onlinelibrary.wiley.com\/doi\/10.1002\/bmc.70448"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4,19]]},"references-count":26,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2026,6]]}},"alternative-id":["10.1002\/bmc.70448"],"URL":"https:\/\/doi.org\/10.1002\/bmc.70448","archive":["Portico"],"relation":{},"ISSN":["0269-3879","1099-0801"],"issn-type":[{"value":"0269-3879","type":"print"},{"value":"1099-0801","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,4,19]]},"assertion":[{"value":"2026-02-26","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-04-03","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-04-19","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70448"}}