{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T15:09:57Z","timestamp":1790435397637,"version":"4.1.0"},"reference-count":15,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2019,5,7]],"date-time":"2019-05-07T00:00:00Z","timestamp":1557187200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100008590","name":"STROKE-Riksf\u00f6rbundet","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100008590","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Brain and Behavior"],"published-print":{"date-parts":[[2019,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>Data on the long\u2010term time course of poststroke functional outcome is limited. We investigated changes in functional outcome over 5\u00a0years after stroke in a hospital based cohort.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods<\/jats:title>\n                    <jats:p>\n                      Consecutive patients who were independent in activities of daily living (ADL) and admitted to a Stroke Unit at Skaraborg Hospital, Sweden for a first acute stroke from 2007 to 2009 (\n                      <jats:italic>n<\/jats:italic>\n                      \u00a0=\u00a01,421) were followed\u2010up after 3\u00a0months and thereafter annually over 5\u00a0years using a postal questionnaire. Clinical variables at acute stroke and 3\u00a0months post stroke were obtained from the Swedish Stroke Register. ADL dependency was defined as dependence in dressing, toileting or indoor mobility.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The proportions of survivors who reported ADL dependency remained stable throughout follow\u2010up (19%\u201322%). However, among survivors who were ADL independent at 3\u00a0months, about 3% deteriorated to dependency each year. Deterioration was predicted by age (HR 1.11; 95% CI 1.08\u20131.13), diabetes (HR 1.65; 95% CI 1.12\u20132.44), NIHSS score (HR 1.07; 95% CI 1.04\u20131.10), and self\u2010perceived unmet care needs one year post stroke (HR 2.01; 95% CI 1.44\u20132.81). Transitions from ADL dependency to independence occurred mainly during the first year post stroke. Improvement was negatively predicted by living alone before stroke (HR 0.41 95% CI 0.19\u20130.91), NIHSS score (HR 0.90; 95% CI 0.86\u20130.95) and ischemic stroke (vs. hemorrhagic stroke), HR 0.39; 95% CI 0.17\u20130.89.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Transitions between ADL independence and dependency occur up to 5\u00a0years after stroke. Some of the factors predicting these transitions are potentially modifiable.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/brb3.1300","type":"journal-article","created":{"date-parts":[[2019,5,8]],"date-time":"2019-05-08T00:09:59Z","timestamp":1557274199000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":46,"title":["Changes in functional outcome over five years after stroke"],"prefix":"10.1002","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6454-9575","authenticated-orcid":false,"given":"\u00c5sa","family":"Rejn\u00f6","sequence":"first","affiliation":[{"name":"Department of Medicine Skaraborg Hospital Sk\u00f6vde Sk\u00f6vde Sweden"},{"name":"Department of Health Sciences University West Trollh\u00e4ttan Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Salmir","family":"Nasic","sequence":"additional","affiliation":[{"name":"Research and Development Centre Skaraborg Hospital Sk\u00f6vde Sk\u00f6vde Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kerstin","family":"Bj\u00e4lkefur","sequence":"additional","affiliation":[{"name":"Department of Health and Social Care Municipality of Lidk\u00f6ping Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eric","family":"Bertholds","sequence":"additional","affiliation":[{"name":"Department of Medicine Skaraborg Hospital Sk\u00f6vde Sk\u00f6vde Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katarina","family":"Jood","sequence":"additional","affiliation":[{"name":"Institute of Neuroscience and Physiology, Department of Clinical Neuroscience The Sahlgrenska Academy at University of Gothenburg Gothenburg Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,5,7]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1747-4949.2010.00557.x"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0170204"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.109.549576"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.0000260102.97954.9c"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.0000012515.66889.24"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1747-4949.2012.00967.x"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.113.001584"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1159\/000364938"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/YCO.0b013e3282f3ad89"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13524-011-0032-5"},{"key":"e_1_2_9_12_1","unstructured":"Riks\u2010Stroke. (2011).Riks\u2010Stroke \u00e5rsrapport 2010[The Swedish stroke register annual report 2010].Riks\u2010Stroke. [Swedish Stroke Register] (in Swedish). Retrieved fromhttp:\/\/www.riks-stroke.org\/content\/analyser\/Riks-Stroke_%C5rsrapport2010.pdf"},{"issue":"12","key":"e_1_2_9_13_1","first-page":"e461","article-title":"Association between different types of social support and medication adherence","volume":"18","author":"Scheurer D.","year":"2012","journal-title":"American Journal of Managed Care"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.114.006538"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.0000195180.69904.f2"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pmed.1001033"}],"container-title":["Brain and Behavior"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/brb3.1300","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/brb3.1300","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/brb3.1300","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,10]],"date-time":"2023-09-10T20:15:46Z","timestamp":1694376946000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/brb3.1300"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,5,7]]},"references-count":15,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2019,6]]}},"alternative-id":["10.1002\/brb3.1300"],"URL":"https:\/\/doi.org\/10.1002\/brb3.1300","archive":["Portico"],"relation":{},"ISSN":["2162-3279","2162-3279"],"issn-type":[{"value":"2162-3279","type":"print"},{"value":"2162-3279","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,5,7]]},"assertion":[{"value":"2019-03-12","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-03-14","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-05-07","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e01300"}}