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It is noteworthy that only a few studies report the STN\u2010DBS for Tourette's syndrome (TS). Globus pallidus interna (GPi)\u2010DBS is the one of the most common targets for TS. So, this paper aims to investigate the neural oscillations in STN and GPi as well as the DBS effect between these two targets in same patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The local field potentials (LFPs) were simultaneously recorded from the bilateral GPi and STN in four patients with TS. The LFPs were decomposed into neural oscillations, and the frequency and time\u2013frequency characteristics of the neural oscillations were analyzed across the conditions of resting, poststimulation, and movement.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>No difference of resting LFP was found between the two targets. The poststimulation period spectral power revealed the high beta and gamma oscillations were recovered after GPi\u2010DBS but remained attenuated after STN\u2010DBS. The STN beta oscillation has fewer changes during tics than voluntary movement, and the gamma oscillation was elevated when the tics appeared.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The high beta and gamma oscillations in GPi restored after GPi\u2010DBS, but not STN\u2010DBS. High beta and gamma oscillations may have physiological function in resisting tics in TS. The cortex compensation effect might be interfered by the STN\u2010DBS due to the influence on the hyper\u2010direct pathway but not GPi\u2010DBS.<\/jats:p><\/jats:sec>","DOI":"10.1002\/brb3.1450","type":"journal-article","created":{"date-parts":[[2019,10,24]],"date-time":"2019-10-24T16:30:06Z","timestamp":1571934606000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":21,"title":["Deep brain stimulation modulates pallidal and subthalamic neural oscillations in Tourette's syndrome"],"prefix":"10.1002","volume":"9","author":[{"given":"Guan\u2010Yu","family":"Zhu","sequence":"first","affiliation":[{"name":"Department of Neurosurgery Beijing Tiantan Hospital Capital Medical University Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xin\u2010Yi","family":"Geng","sequence":"additional","affiliation":[{"name":"Institute of Science and Technology for Brain\u2010Inspired Intelligence Fudan University 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