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In addition, the VEOS subgroup had a more frequent childhood history of learning disabilities and lower prevalence of right\u2010handedness quotient than the AOS.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The study demonstrates the existence of an increased gradient of clinical severity from AOS to VEOS. In order to improve the prognosis of the early forms of schizophrenia and to reduce the DUP, clinicians need to pay attention to the prodromal manifestations of the disease.<\/jats:p><\/jats:sec>","DOI":"10.1002\/brb3.1495","type":"journal-article","created":{"date-parts":[[2020,1,7]],"date-time":"2020-01-07T09:47:05Z","timestamp":1578390425000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":68,"title":["Early and very early\u2010onset schizophrenia compared with adult\u2010onset schizophrenia: French FACE\u2010SZ database"],"prefix":"10.1002","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7765-1117","authenticated-orcid":false,"given":"Nathalie","family":"Coulon","sequence":"first","affiliation":[{"name":"Fondation FondaMental Cr\u00e9teil France"},{"name":"INSERM U955 Translational Psychiatry laboratory AP-HP, DHU Pe-PSY Centre Expert Schizophr\u00e9nie P\u00f4le de Psychiatrie et d'Addictologie des 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