{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,4]],"date-time":"2025-10-04T18:33:29Z","timestamp":1759602809313,"version":"3.41.2"},"reference-count":39,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2020,2,17]],"date-time":"2020-02-17T00:00:00Z","timestamp":1581897600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"the Projects of National Science Foundation of China","award":["No. 81873799"],"award-info":[{"award-number":["No. 81873799"]}]},{"name":"Wenzhou Municipal Sci-Tech Bureau Program","award":["Y20160002"],"award-info":[{"award-number":["Y20160002"]}]},{"name":"National Key Technology Research and Development Program of the Ministry of Science and Technology of China","award":["2015BAI13B01"],"award-info":[{"award-number":["2015BAI13B01"]}]},{"name":"Projects of National Science Foundation of China","award":["81873799"],"award-info":[{"award-number":["81873799"]}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Brain and Behavior"],"published-print":{"date-parts":[[2020,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>The association between prediabetes and functional outcome in cerebrovascular diseases is controversial. No study has explored the relationship between prediabetes and functional outcome in intracerebral hemorrhage patients. Our study aimed to explore the association between prediabetes and functional outcome in intracerebral hemorrhage patients 1\u00a0month poststroke.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>One hundred and fifty intracerebral hemorrhage patients were consecutively recruited within the first 24\u00a0hr after admission and were followed up for 1\u00a0month. Patients were divided into a diabetes mellitus group, a prediabetes group, and a nondiabetic group by fasting glucose levels, 2\u2010hr postprandial blood glucose levels, and glycosylated hemoglobin levels. Patients with modified Rankin Scale scores\u00a0&gt;2 at 1\u00a0month were defined as having a poor functional outcome.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The prediabetes group had a higher risk of poor functional outcome than the nondiabetic group in intracerebral hemorrhage patients (37.9% vs. 9.8%, \u03c7<jats:sup>2<\/jats:sup>\u00a0=\u00a011.521, <jats:italic>p<\/jats:italic>\u00a0=\u00a0.001). According to the logistic regression analyses, prediabetes was associated with a poor functional outcome in intracerebral hemorrhage patients after adjusting for confounding factors (odds ratio\u00a0=\u00a06.167, 95% confidence interval\u00a0=\u00a01.403\u201327.102, <jats:italic>p<\/jats:italic>\u00a0=\u00a0.016).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Our findings show that prediabetes is associated with a poor functional outcome in intracerebral hemorrhage patients 1\u00a0month poststroke.<\/jats:p><\/jats:sec>","DOI":"10.1002\/brb3.1530","type":"journal-article","created":{"date-parts":[[2020,2,17]],"date-time":"2020-02-17T17:43:30Z","timestamp":1581961410000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Prediabetes is associated with poor functional outcome in patients with intracerebral hemorrhage"],"prefix":"10.1002","volume":"10","author":[{"given":"Qiongzhang","family":"Wang","sequence":"first","affiliation":[{"name":"Department of Neurology The First Affiliated Hospital of Wenzhou Medical University Wenzhou Zhejiang China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guiqian","family":"Huang","sequence":"additional","affiliation":[{"name":"Department of Neurology The First Affiliated Hospital of Wenzhou Medical University Wenzhou Zhejiang China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fei","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Neurology The Deqing People's Hospital Huzhou Zhejiang China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pinglang","family":"Hu","sequence":"additional","affiliation":[{"name":"Department of Neurology The First Affiliated Hospital of Wenzhou Medical University Wenzhou Zhejiang China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wenwei","family":"Ren","sequence":"additional","affiliation":[{"name":"Department of Neurology The First Affiliated Hospital of Wenzhou Medical University Wenzhou Zhejiang China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaoqian","family":"Luan","sequence":"additional","affiliation":[{"name":"Department of Neurology The First Affiliated Hospital of Wenzhou Medical University Wenzhou Zhejiang China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"ChengYe","family":"Zhou","sequence":"additional","affiliation":[{"name":"Department of Neurology The First Affiliated Hospital of Wenzhou Medical University Wenzhou Zhejiang China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5493-4357","authenticated-orcid":false,"given":"Jincai","family":"He","sequence":"additional","affiliation":[{"name":"Department of Neurology The First Affiliated Hospital of Wenzhou Medical University Wenzhou Zhejiang China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2020,2,17]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.2337\/dc14-S081"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.110.608166"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.111.632950"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000003031"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamaneurol.2016.2619"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00221-015-4269-x"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.116.003477"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.113.675983"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(13)61953-4"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.medin.2014.10.008"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1159\/000360810"},{"issue":"2","key":"e_1_2_9_13_1","first-page":"372","article-title":"Oral glucose tolerance test (OGTT) for diagnosis of diabetes mellitus","volume":"63","author":"Hagura R.","year":"2005","journal-title":"Nihon Rinsho"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp-2012-303365"},{"issue":"4","key":"e_1_2_9_15_1","first-page":"203","article-title":"Risk factors impact on the long\u2010term survival after hemorrhagic stroke","volume":"63","author":"Kojic B.","year":"2009","journal-title":"Medicinski Arhiv"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.3389\/fneur.2019.01073"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.0000149628.80251.b8"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1177\/0148607106030002157"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.2147\/NDT.S128807"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.4103\/0972-2327.104333"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/ane.12577"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.115.008818"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1212\/01.WNL.0000094326.30791.2D"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.2337\/dc18-2472"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.0000088060.83709.2C"},{"key":"e_1_2_9_26_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12028-010-9355-0"},{"key":"e_1_2_9_27_1","doi-asserted-by":"publisher","DOI":"10.1038\/srep36220"},{"key":"e_1_2_9_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(12)60283-9"},{"key":"e_1_2_9_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clineuro.2013.12.018"},{"key":"e_1_2_9_30_1","doi-asserted-by":"publisher","DOI":"10.3171\/2008.8.JNS08445"},{"key":"e_1_2_9_31_1","doi-asserted-by":"publisher","DOI":"10.1159\/000475667"},{"key":"e_1_2_9_32_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12889-019-6445-6"},{"key":"e_1_2_9_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clineuro.2015.01.020"},{"key":"e_1_2_9_34_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.116.025250"},{"key":"e_1_2_9_35_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-7091-0693-8_67"},{"key":"e_1_2_9_36_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pmed.1001033"},{"key":"e_1_2_9_37_1","doi-asserted-by":"publisher","DOI":"10.1179\/1743132812Y.0000000141"},{"key":"e_1_2_9_38_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10072-014-2057-1"},{"key":"e_1_2_9_39_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jstrokecerebrovasdis.2017.11.019"},{"key":"e_1_2_9_40_1","doi-asserted-by":"publisher","DOI":"10.1179\/016164110X12681290831441"}],"container-title":["Brain and Behavior"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fbrb3.1530","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/brb3.1530","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/brb3.1530","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/brb3.1530","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,6]],"date-time":"2023-09-06T12:05:53Z","timestamp":1694001953000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/brb3.1530"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,2,17]]},"references-count":39,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2020,4]]}},"alternative-id":["10.1002\/brb3.1530"],"URL":"https:\/\/doi.org\/10.1002\/brb3.1530","archive":["Portico"],"relation":{},"ISSN":["2162-3279","2162-3279"],"issn-type":[{"type":"print","value":"2162-3279"},{"type":"electronic","value":"2162-3279"}],"subject":[],"published":{"date-parts":[[2020,2,17]]},"assertion":[{"value":"2019-07-21","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-12-23","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-02-17","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e01530"}}