{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T18:49:31Z","timestamp":1788893371496,"version":"build-2803163510"},"reference-count":64,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2020,3,10]],"date-time":"2020-03-10T00:00:00Z","timestamp":1583798400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Shaanxi Provincial Science and Technology Development Funds","award":["2017-032"],"award-info":[{"award-number":["2017-032"]}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Brain and Behavior"],"published-print":{"date-parts":[[2020,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Previous voxel\u2010based morphometry (VBM) studies have revealed changes in brain structure in patients with vestibular migraine (VM); these findings have improved the present understanding of pathophysiology. Few other studies have assessed the association between structural changes and the severity of dizziness in VM. This study aimed to examine the structural changes and cortical morphometric features associated with migraine and vertigo attacks in patients with VM.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Twenty patients with VM and 20 healthy normal volunteers were scanned on a 3\u2010tesla MRI scanner. The gray matter volume (GMV) was estimated using the automated Computational Anatomy Toolbox (CAT12). The relationship between clinical parameters and morphometric abnormalities was also analyzed in VM.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Compared with controls, VM patients have decreased GMV in the prefrontal cortex (PFC), posterior insula\u2013operculum regions, inferior parietal gyrus, and supramarginal gyrus. Moreover, patient scores on the Dizziness Handicap Inventory (DHI) score showed a negative correlation with GMV in the posterior insula\u2013operculum regions.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>These findings demonstrated abnormality in the central vestibular cortex and correlations between dizziness severity and GMV in core regions of the vestibular cortex of VM patients, suggesting a pathophysiological role of these core vestibular regions in VM patients.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/brb3.1572","type":"journal-article","created":{"date-parts":[[2020,3,10]],"date-time":"2020-03-10T23:25:04Z","timestamp":1583882704000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":38,"title":["Altered structure of the vestibular cortex in patients with vestibular migraine"],"prefix":"10.1002","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4946-1302","authenticated-orcid":false,"given":"Xia","family":"Zhe","sequence":"first","affiliation":[{"name":"Department of MRI Diagnosis Shaanxi Provincial People's Hospital Xi'an China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jie","family":"Gao","sequence":"additional","affiliation":[{"name":"Department of MRI Diagnosis Shaanxi Provincial People's Hospital Xi'an China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Neurology Shaanxi Provincial People's Hospital Xi'an China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9633-8521","authenticated-orcid":false,"given":"Dongsheng","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of MRI Diagnosis Shaanxi Provincial People's Hospital Xi'an China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Min","family":"Tang","sequence":"additional","affiliation":[{"name":"Department of MRI Diagnosis Shaanxi Provincial People's Hospital Xi'an China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xuejiao","family":"Yan","sequence":"additional","affiliation":[{"name":"Department of MRI Diagnosis Shaanxi Provincial People's Hospital Xi'an China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fuxia","family":"Bai","sequence":"additional","affiliation":[{"name":"Department of MRI Diagnosis Shaanxi Provincial People's Hospital Xi'an China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xin","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of MRI Diagnosis Shaanxi Provincial People's Hospital Xi'an China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ze","family":"Zou","sequence":"additional","affiliation":[{"name":"Department of MRI Diagnosis Shaanxi Provincial People's Hospital Xi'an China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weibo","family":"Chen","sequence":"additional","affiliation":[{"name":"Philips Healthcare Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoyan","family":"Lei","sequence":"additional","affiliation":[{"name":"Department of MRI Diagnosis Shaanxi Provincial People's Hospital Xi'an China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoling","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of MRI Diagnosis Shaanxi Provincial People's Hospital Xi'an China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,3,10]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awh416"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.3109\/00016489.2014.969382"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.3233\/VES-130477"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jns.2015.06.059"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pneurobio.2008.09.018"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejpain.2004.11.001"},{"issue":"1","key":"e_1_2_10_8_1","first-page":"9","article-title":"Definition of balance and cognition related to disability levels in vestibular migraine patients","volume":"55","author":"Balci B.","year":"2018","journal-title":"Archives of Neuropsychiatry"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jad.2017.03.039"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.3640-14.2015"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/124.6.1182"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.45.1.42"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1177\/0333102415597890"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awn042"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-014-7548-8"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-444-63622-5.00006-1"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-015-7905-2"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/ana.22063"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cogbrainres.2004.02.007"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1526-4637.2011.01183.x"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jneumeth.2014.07.008"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1152\/jn.00907.2017"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.2480-16.2016"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.1152\/jn.00009.2016"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awg032"},{"key":"e_1_2_10_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(13)70107-8"},{"key":"e_1_2_10_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neucli.2012.06.001"},{"key":"e_1_2_10_28_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/101.1.83"},{"key":"e_1_2_10_29_1","doi-asserted-by":"publisher","DOI":"10.1093\/cercor\/bhn036"},{"key":"e_1_2_10_30_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.1010-12.2012"},{"key":"e_1_2_10_31_1","doi-asserted-by":"publisher","DOI":"10.1177\/0333102413485658"},{"key":"e_1_2_10_32_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.2008.03745.x"},{"key":"e_1_2_10_33_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.57.8.1522"},{"key":"e_1_2_10_34_1","doi-asserted-by":"publisher","DOI":"10.1177\/0333102414532378"},{"issue":"3","key":"e_1_2_10_35_1","first-page":"4311","article-title":"A meta\u2010analysis of voxel\u2010based morphometric studies on migraine","volume":"8","author":"Hu W.","year":"2015","journal-title":"International Journal of Clinical & Experimental Medicine"},{"key":"e_1_2_10_36_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00221-010-2340-1"},{"key":"e_1_2_10_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pain.2010.12.025"},{"key":"e_1_2_10_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2008.06.026"},{"key":"e_1_2_10_39_1","doi-asserted-by":"publisher","DOI":"10.1002\/ana.10726"},{"key":"e_1_2_10_40_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-009-0149-2"},{"key":"e_1_2_10_41_1","doi-asserted-by":"publisher","DOI":"10.3233\/VES-2012-0453"},{"key":"e_1_2_10_42_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroscience.2012.03.028"},{"key":"e_1_2_10_43_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2011.12.072"},{"key":"e_1_2_10_44_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-016-8349-z"},{"key":"e_1_2_10_45_1","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000237539.09942.06"},{"key":"e_1_2_10_46_1","doi-asserted-by":"publisher","DOI":"10.1177\/0333102414527650"},{"key":"e_1_2_10_47_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1526-4610.2010.01745.x"},{"key":"e_1_2_10_48_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-013-7201-y"},{"key":"e_1_2_10_49_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000000496"},{"key":"e_1_2_10_50_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1526-4610.2009.01544.x"},{"key":"e_1_2_10_51_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2018.02.006"},{"key":"e_1_2_10_52_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2007.08.016"},{"key":"e_1_2_10_53_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1526-4610.2008.01133.x"},{"key":"e_1_2_10_54_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(09)70107-3"},{"key":"e_1_2_10_55_1","doi-asserted-by":"publisher","DOI":"10.1177\/0333102413498940"},{"key":"e_1_2_10_56_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuropsychologia.2008.11.033"},{"key":"e_1_2_10_57_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10072-016-2618-6"},{"issue":"53","key":"e_1_2_10_58_1","first-page":"1","article-title":"Vestibular function in the temporal and parietal cortex: Distinct velocity and inertial processing pathways","volume":"8","author":"Ventre\u2010Dominey J.","year":"2014","journal-title":"Frontiers Integrative Neuroscience"},{"issue":"2","key":"e_1_2_10_59_1","first-page":"308","article-title":"Response to: Migraine and vertigo: a marriage of convenience?. Headache","volume":"51","author":"Brevern M.","year":"2011","journal-title":"The Journal of Head and Face Pain"},{"key":"e_1_2_10_60_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.crad.2019.07.015"},{"key":"e_1_2_10_61_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tics.2008.05.005"},{"key":"e_1_2_10_62_1","doi-asserted-by":"publisher","DOI":"10.1089\/brain.2017.0544"},{"key":"e_1_2_10_63_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpsychores.2017.10.007"},{"key":"e_1_2_10_64_1","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000004824"},{"key":"e_1_2_10_65_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2011.12.032"}],"container-title":["Brain and Behavior"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fbrb3.1572","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/brb3.1572","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/brb3.1572","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/brb3.1572","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,6]],"date-time":"2023-09-06T08:04:34Z","timestamp":1693987474000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/brb3.1572"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,3,10]]},"references-count":64,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2020,4]]}},"alternative-id":["10.1002\/brb3.1572"],"URL":"https:\/\/doi.org\/10.1002\/brb3.1572","archive":["Portico"],"relation":{"has-review":[{"id-type":"doi","id":"10.1002\/BRB3.1572\/v2\/response1","asserted-by":"object"},{"id-type":"doi","id":"10.1002\/BRB3.1572\/v2\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1002\/BRB3.1572\/v3\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1002\/BRB3.1572\/v1\/review1","asserted-by":"object"},{"id-type":"doi","id":"10.1002\/BRB3.1572\/v1\/review2","asserted-by":"object"},{"id-type":"doi","id":"10.1002\/BRB3.1572\/v3\/response1","asserted-by":"object"},{"id-type":"doi","id":"10.1002\/BRB3.1572\/v2\/review1","asserted-by":"object"},{"id-type":"doi","id":"10.1002\/BRB3.1572\/v1\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1002\/BRB3.1572\/v2\/review2","asserted-by":"object"},{"id-type":"doi","id":"10.1002\/BRB3.1572\/v1\/review3","asserted-by":"object"}]},"ISSN":["2162-3279","2162-3279"],"issn-type":[{"value":"2162-3279","type":"print"},{"value":"2162-3279","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,3,10]]},"assertion":[{"value":"2019-08-13","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-01-30","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-03-10","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e01572"}}