{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,18]],"date-time":"2026-03-18T01:25:42Z","timestamp":1773797142919,"version":"3.50.1"},"reference-count":107,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2020,6,7]],"date-time":"2020-06-07T00:00:00Z","timestamp":1591488000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Postgraduate Program in Health and Development, Federal University of Mato Grosso do Sul, Brazil and Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior (CAPES), Brazil","award":["001"],"award-info":[{"award-number":["001"]}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Brain and Behavior"],"published-print":{"date-parts":[[2020,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Cultural traditions attribute to pineal gland an important role for spiritual experiences. Mediumship and spirit possession are cultural phenomena found worldwide which have been described as having dissociative and psychotic\u2010like characteristics, but with nonpathological aspects. A sympathetic activation pattern in response to spirit possession has been reported in some studies, but empirical data on pineal gland is scarce in this context.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      We aimed to investigate pineal gland and pituitary volumes, as well as urinary 6\u2010sulfatoxymelatonin levels in 16 alleged mediums (Medium Group\u2010MG) compared with 16 healthy nonmedium controls (Control Group) (Experiment 1). Furthermore, we aimed to evaluate urinary 6\u2010sulfatoxymelatonin and stress reactivity in GM (\n                      <jats:italic>n<\/jats:italic>\n                      \u00a0=\u00a010) under different physiological conditions (Experiment 2).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>In Experiment 1, MG presented higher scores of anomalous experiences, but there were no between\u2010group differences regarding mental health or subjective sleep quality. Similar pineal gland and pituitary volumes were observed between groups. There were no between\u2010group differences in urinary 6\u2010sulfatoxymelatonin collected under equivalent baseline conditions. In Experiment 2, the rise of anxiety and heart rate in response to mediumistic experience was intermediate between a nonstressful control task (reading) and a stressful control task (Trier Social Stress Test\u2014TSST). No significant differences were observed in 6\u2010sulfatoxymelatonin urinary levels between the three conditions. The pattern of stress reactivity during the TSST was normal, but with an attenuated salivary cortisol response.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The normal neuroimaging and stress reactivity findings in MG contrast with the abnormal results usually observed in subjects with psychotic and dissociative disorders.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/brb3.1693","type":"journal-article","created":{"date-parts":[[2020,6,7]],"date-time":"2020-06-07T09:47:57Z","timestamp":1591523277000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["\u201cSeat of the soul\u201d? The structure and function of the pineal gland in women with alleged spirit possession\u2014Results of two experimental studies"],"prefix":"10.1002","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1280-4490","authenticated-orcid":false,"suffix":"Jr.","given":"Marco Aur\u00e9lio Vinhosa","family":"Bastos","sequence":"first","affiliation":[{"name":"Postgraduate Program in Health and Development Federal University of Mato Grosso do Sul Campo Grande Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paulo Roberto Haidamus de Oliveira","family":"Bastos","sequence":"additional","affiliation":[{"name":"Postgraduate Program in Health and Development Federal University of Mato Grosso do Sul Campo Grande Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Loyn\u00e1 Eu\u00e1 Flores","family":"e Paez","sequence":"additional","affiliation":[{"name":"School of Medicine Federal University of Mato Grosso do Sul Campo Grande Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Edna Oliveira","family":"de Souza","sequence":"additional","affiliation":[{"name":"ABRAPE Campo Grande Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Danielle","family":"Bogo","sequence":"additional","affiliation":[{"name":"School of Pharmaceutical Sciences Federal University of Mato Grosso do Sul Campo Grande Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Renata Trentin","family":"Perdomo","sequence":"additional","affiliation":[{"name":"School of Pharmaceutical Sciences Federal University of Mato Grosso do Sul Campo Grande Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Renata Boschi","family":"Portella","sequence":"additional","affiliation":[{"name":"School of Medicine Federal University of Mato Grosso do Sul Campo Grande Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jorge Guilherme Okanobo","family":"Ozaki","sequence":"additional","affiliation":[{"name":"Sonimed Imaging Clinic Campo Grande Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"suffix":"Jr.","given":"D\u00e9cio","family":"Iandoli","sequence":"additional","affiliation":[{"name":"School of Medicine Anhanguera\u2010Uniderp University Campo Grande Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giancarlo","family":"Lucchetti","sequence":"additional","affiliation":[{"name":"School of Medicine Federal University of Juiz de Fora Juiz de Fora Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2020,6,7]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neubiorev.2013.11.005"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.3174\/ajnr.A2275"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuropsychologia.2006.11.020"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/00043764-199611000-00010"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/0165-1781(92)90070-J"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/bem.10053"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnins.2018.00536"},{"issue":"7","key":"e_1_2_9_9_1","first-page":"301","article-title":"Social effects of oxytocin in humans: Context and person matter","volume":"15","author":"Bartz J. 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