{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,30]],"date-time":"2026-05-30T02:31:53Z","timestamp":1780108313446,"version":"3.54.0"},"reference-count":23,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2020,8,25]],"date-time":"2020-08-25T00:00:00Z","timestamp":1598313600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Brain and Behavior"],"published-print":{"date-parts":[[2020,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To study the changes of white matter tracts in precentral gyrus and postcentral gyrus during normal brain aging process by analyzing fractional anisotropy (FA) values obtained from diffusion tensor imaging (DTI) technology.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Magnetic resonance imaging (MRI) and diffusion tensor imaging (DTI) were conducted on 120 healthy right\u2010handed subjects. The subjects were separated into four age groups, namely Young Male\/Female (&lt;45\u00a0years old) and Senior Male\/Female (&gt;45\u00a0years old). Each subject undertakes routine MRI and DTI scans. Left\/right precentral and left\/right postcentral gyrus are automatically detected on the image. The area for region of interest (ROI) is set to be 18\u00a0\u00b1\u00a02\u00a0mm<jats:sup>2<\/jats:sup>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>For each age group, the FA values of white matter in precentral gyrus and postcentral gyrus are statistically different (<jats:italic>p<\/jats:italic>\u00a0&lt;\u00a0.05) in both left and right sides of the brain across different age groups and genders. Additionally, the FA values are statistically different (<jats:italic>p<\/jats:italic>\u00a0&lt;\u00a0.05) between two young and senior age groups across different genders, brain regions, and hemispheres.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The FA values of precentral gyrus and postcentral gyrus are statistically different across genders, age groups, and hemispheres. Additionally, the FA values of both precentral gyrus and postcentral gyrus decrease over time, which is a strong indication of aging.<\/jats:p><\/jats:sec>","DOI":"10.1002\/brb3.1758","type":"journal-article","created":{"date-parts":[[2020,8,26]],"date-time":"2020-08-26T13:22:25Z","timestamp":1598448145000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":23,"title":["Diffusion tensor imaging study of brain precentral gyrus and postcentral gyrus during normal brain aging process"],"prefix":"10.1002","volume":"10","author":[{"given":"Ling","family":"Zhou","sequence":"first","affiliation":[{"name":"Department of MRI Xinle City Hospital Xinle Hebei China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Na","family":"Tian","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases Xinle City Hospital Xinle Hebei China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7640-2634","authenticated-orcid":false,"given":"Zuo\u2010Jun","family":"Geng","sequence":"additional","affiliation":[{"name":"Department of Radiology The Second Hospital of Hebei Medical University Shijiazhuang Hebei China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bing\u2010Kun","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of MRI Xinle City Hospital Xinle Hebei China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li\u2010Ying","family":"Dong","sequence":"additional","affiliation":[{"name":"Department of MRI Xinle City Hospital Xinle Hebei China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mei\u2010Rong","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of CT The Fifth People's Hospital of Hengshui Hengshui Hebei China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,8,25]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12031-007-0029-0"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0006-3495(94)80775-1"},{"key":"e_1_2_9_4_1","volume-title":"The learning brain: Lessons for education","author":"Blakemore S.\u2010J.","year":"2005"},{"issue":"4","key":"e_1_2_9_5_1","first-page":"647","article-title":"MR imaging and localized proton spectroscopy of the precentral gyrus in amyotrophic lateral sclerosis","volume":"21","author":"Bowen B. 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