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Magnetoencephalographic (MEG) data of 18 healthy children and 22 BECTS patients were recorded in order to construct a functional connectivity (FC) network, which was quantified by graph theory (GT).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The mean age of the control group was 7.94\u00a0\u00b1\u00a01.89\u00a0years, and the mean age of BECTS patients was 8.14\u00a0\u00b1\u00a01.73\u00a0years. Our results show that the WISC\u2010IV index scores in the BECTS group were significantly lower than those in the control group. Besides, the FC network pattern of BECTS patients changed significantly in the 12\u201330, 30\u201380, and 250\u2013500\u00a0Hz frequency band. The local functional connections between posterior cingulate cortex (PCC) and frontal lobe varied significantly in 12\u201330, 80\u2013250, and 250\u2013500\u00a0Hz. Our GT analysis shows that the connection strength of BECTS patients increases significantly in the 12\u201330\u00a0Hz frequency band, the path length decreases significantly in the 12\u201330\u00a0Hz and 30\u201380\u00a0Hz frequency bands, with the clustering coefficient decreasing significantly in the 12\u201330\u00a0Hz, 30\u201380\u00a0Hz, and 250\u2013500\u00a0Hz frequency bands. Correlation analysis showed that the full\u2010scale IQ (FSIQ) was positively correlated with the 12\u201330\u00a0Hz clustering coefficient, verbal comprehension index (VCI) was positively correlated with the 250\u2013500\u00a0Hz clustering coefficient, perceptual reasoning index (PRI) was positively correlated with the 12\u201330\u00a0Hz clustering coefficient, and perceptual reasoning index (PSI) was negatively correlated with the 12\u201330\u00a0Hz path length.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>There is a trend of cognitive impairment in patients with early BECTS. This trend of cognitive impairment in early BECTS children may be related to the changes in the FC network pattern.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/brb3.1854","type":"journal-article","created":{"date-parts":[[2020,9,22]],"date-time":"2020-09-22T08:07:43Z","timestamp":1600762063000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":20,"title":["The relationship between epilepsy and cognitive function in benign childhood epilepsy with centrotemporal spikes"],"prefix":"10.1002","volume":"10","author":[{"given":"Yihan","family":"Li","sequence":"first","affiliation":[{"name":"Department of Neurology Nanjing Brain Hospital Nanjing Medical University Nanjing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yulei","family":"Sun","sequence":"additional","affiliation":[{"name":"Department of Neurology Nanjing Brain Hospital Nanjing Medical University Nanjing 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