{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T15:02:15Z","timestamp":1772118135729,"version":"3.50.1"},"reference-count":17,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2020,11,28]],"date-time":"2020-11-28T00:00:00Z","timestamp":1606521600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Brain and Behavior"],"published-print":{"date-parts":[[2021,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Study Objectives<\/jats:title>\n                    <jats:p>Narcolepsy type 1 (NT1) is a chronic rare hypersomnia of central origin requiring a combination of behavioral and pharmacological treatments. During the coronavirus disease 2019 (COVID\u201019) pandemic, in Italy the population was forced into a lockdown. With this study, we aimed to describe the lockdown impact on NT1 symptom management, according to different patients' working schedule.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>In the period between 10 April and 15 May 2020, we performed routine follow\u2010up visits by telephone (as recommended during the COVID\u201019 emergency) to 50 patients &gt;18\u00a0years old (40% males) under stable long\u2010term treatment. We divided patients into three groups: unchanged working schedule, forced working\/studying at home, and those who lost their job (\u201clost occupation\u201d). Current sleep\u2013wake habit and symptom severity were compared with prelockdown assessment (six months before) in the three patient groups.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>At assessment, 20, 22, and eight patients belonged to the unchanged, working\/studying at home, and lost occupation groups, respectively. While in the lost occupation group, there were no significant differences compared with prepandemic assessment, the patients with unchanged schedules reported more nocturnal awakenings, and NT1 patients working\/studying at home showed an extension of nocturnal sleep time, more frequent daytime napping, improvement of daytime sleepiness, and a significant increase in their body mass index. Sleep\u2010related paralysis\/hallucinations, automatic behaviors, cataplexy, and disturbed nocturnal sleep did not differ.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Narcolepsy type 1 patients working\/studying at home intensified behavioral interventions (increased nocturnal sleep time and daytime napping) and ameliorated daytime sleepiness despite presenting with a slight, but significant, increase of weight.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/brb3.1955","type":"journal-article","created":{"date-parts":[[2020,11,28]],"date-time":"2020-11-28T05:43:35Z","timestamp":1606542215000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":20,"title":["Impact of COVID\u201019 pandemic lockdown on narcolepsy type 1 management"],"prefix":"10.1002","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2058-2047","authenticated-orcid":false,"given":"Emanuela","family":"Postiglione","sequence":"first","affiliation":[{"name":"Department of Biomedical and Neuromotor Sciences (DIBINEM) University of Bologna Bologna Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2294-9551","authenticated-orcid":false,"given":"Fabio","family":"Pizza","sequence":"additional","affiliation":[{"name":"Department of Biomedical and Neuromotor Sciences (DIBINEM) University of Bologna Bologna Italy"},{"name":"IRCCS Istituto delle Scienze Neurologiche di Bologna Bologna Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5194-375X","authenticated-orcid":false,"given":"Francesca","family":"Ingravallo","sequence":"additional","affiliation":[{"name":"Department of Medical and Surgical Sciences (DIMEC) University of Bologna Bologna Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9051-7091","authenticated-orcid":false,"given":"Luca","family":"Vignatelli","sequence":"additional","affiliation":[{"name":"IRCCS Istituto delle Scienze Neurologiche di Bologna Bologna Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9702-8314","authenticated-orcid":false,"given":"Marco","family":"Filardi","sequence":"additional","affiliation":[{"name":"Department of Biomedical and Neuromotor Sciences (DIBINEM) University of Bologna Bologna Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9057-2883","authenticated-orcid":false,"given":"Anastasia","family":"Mangiaruga","sequence":"additional","affiliation":[{"name":"Department of Medical and Surgical Sciences (DIMEC) University of Bologna Bologna Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1739-6139","authenticated-orcid":false,"given":"Elena","family":"Antelmi","sequence":"additional","affiliation":[{"name":"Neurology Unit Movement Disorders Division Department of Neurosciences, Biomedicine and Movement Sciences University of Verona Verona Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4316-5684","authenticated-orcid":false,"given":"Monica","family":"Moresco","sequence":"additional","affiliation":[{"name":"IRCCS Istituto delle Scienze Neurologiche di Bologna Bologna Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Claudia","family":"Oriolo","sequence":"additional","affiliation":[{"name":"Endocrinology and Diabetes Prevention and Care Unit Department of Medical and Surgical Sciences (DIMEC) S. Orsola Policlinic University of Bologna Bologna Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4182-3110","authenticated-orcid":false,"given":"Uberto","family":"Pagotto","sequence":"additional","affiliation":[{"name":"Endocrinology and Diabetes Prevention and Care Unit Department of Medical and Surgical Sciences (DIMEC) S. Orsola Policlinic University of Bologna Bologna Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1051-0472","authenticated-orcid":false,"given":"Giuseppe","family":"Plazzi","sequence":"additional","affiliation":[{"name":"IRCCS Istituto delle Scienze Neurologiche di Bologna Bologna Italy"},{"name":"Department of Biomedical, Metabolic and Neural Sciences University of Modena and Reggio\u2010Emilia Modena Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2020,11,28]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"crossref","first-page":"e13052","DOI":"10.1111\/jsr.13052","article-title":"Dealing with sleep problems during home confinement due to the COVID\u201019 outbreak: Practical recommendations from a task force of the European CBT\u2010I Academy","author":"Altena E.","year":"2020","journal-title":"Journal of Sleep Research"},{"key":"e_1_2_8_3_1","volume-title":"International classification of sleep disorders \u2010 third edition (ICSD\u20103)","author":"American Academy of Sleep Medicine","year":"2014"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41582-019-0226-9"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(20)30460-8"},{"key":"e_1_2_8_6_1","doi-asserted-by":"crossref","first-page":"e13074","DOI":"10.1111\/jsr.13074","article-title":"Changes in sleep pattern, sense of time and digital media use during COVID\u201019 lockdown in Italy","author":"Cellini N.","year":"2020","journal-title":"Journal of Sleep Research"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.3389\/fneur.2018.00707"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11325-019-01894-4"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.sleep.2012.08.002"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.psychres.2020.113111"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.5664\/jcsm.4554"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/s15010-020-01420-9"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1093\/sleep\/zsaa066"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.5664\/jcsm.6494"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1097\/NMD.0000000000000918"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1093\/sleep\/24.4.385"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.5664\/jcsm.3004"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1007\/s100720300004"}],"container-title":["Brain and Behavior"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/brb3.1955","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/brb3.1955","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/brb3.1955","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,14]],"date-time":"2023-10-14T01:13:31Z","timestamp":1697246011000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/brb3.1955"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,11,28]]},"references-count":17,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2021,1]]}},"alternative-id":["10.1002\/brb3.1955"],"URL":"https:\/\/doi.org\/10.1002\/brb3.1955","archive":["Portico"],"relation":{"has-review":[{"id-type":"doi","id":"10.1002\/BRB3.1955\/v1\/review1","asserted-by":"object"},{"id-type":"doi","id":"10.1002\/BRB3.1955\/v1\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1002\/BRB3.1955\/v2\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1002\/BRB3.1955\/v2\/response1","asserted-by":"object"}]},"ISSN":["2162-3279","2162-3279"],"issn-type":[{"value":"2162-3279","type":"print"},{"value":"2162-3279","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,11,28]]},"assertion":[{"value":"2020-07-03","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-10-14","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-11-28","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e01955"}}