{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,27]],"date-time":"2026-03-27T08:34:50Z","timestamp":1774600490407,"version":"3.50.1"},"reference-count":50,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2020,12,13]],"date-time":"2020-12-13T00:00:00Z","timestamp":1607817600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Brain and Behavior"],"published-print":{"date-parts":[[2021,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background and Aims<\/jats:title>\n                    <jats:p>Peripheral nerve injury is common with poor functional recovery and consequent high personal and societal costs. Sciatic nerve transection and assessment of recovery using sciatic functional index (SFI) are widely used. SFI is biologically limited as axonal misdirection of axons supplying flexors and extensors in the hindlimb, after nerve injury can lead to synkinetic innervation and function which does not correspond to the degree of axonal regeneration.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We reevaluated the use of traditional metrics such as print length (PL), toe spread (TS), and intermediate toe spread (ITS) as well as hock angle at mid\u2010swing as approaches for determining recovery. We used two alternative approaches in discrete cohorts of rats following common peroneal crush injury, transection with repair and critical gap, using transection with ligation as a negative control. We compared walking track analysis (print) with digital capture and kinematics.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      PL, TS, and ITS varied as expected after injury. The traditional functional index for common peroneal injury using inked prints failed to describe recovery and we derived new indices to describe recovery (all\n                      <jats:italic>R<\/jats:italic>\n                      <jats:sup>2<\/jats:sup>\n                      \u00a0&gt;\u00a00.88,\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0&lt;\u00a0.0001) although pre\u2010injury PFI was never attained by any of the models. Kinematic analysis identified hock angle at mid\u2010swing as a useful predictor of recovery (\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0&lt;\u00a0.0001).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Interpretation<\/jats:title>\n                    <jats:p>Using complementary approaches.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/brb3.1968","type":"journal-article","created":{"date-parts":[[2020,12,13]],"date-time":"2020-12-13T23:18:59Z","timestamp":1607901539000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Revitalizing the common peroneal function index for assessing functional recovery following nerve injury"],"prefix":"10.1002","volume":"11","author":[{"given":"Calder","family":"Fontaine","sequence":"first","affiliation":[{"name":"Department of Clinical Sciences Cornell College of Veterinary Medicine Cornell University Ithaca NY USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4761-6721","authenticated-orcid":false,"given":"Eric A.","family":"Yeager","sequence":"additional","affiliation":[{"name":"Department of Clinical Sciences Cornell College of Veterinary Medicine Cornell University Ithaca NY USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Sledziona","sequence":"additional","affiliation":[{"name":"Department of Clinical Sciences Cornell College of Veterinary Medicine Cornell University Ithaca NY USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amanda K.","family":"Jones","sequence":"additional","affiliation":[{"name":"Department of Clinical Sciences Cornell College of Veterinary Medicine Cornell University Ithaca NY USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9309-5261","authenticated-orcid":false,"given":"Jonathan","family":"Cheetham","sequence":"additional","affiliation":[{"name":"Department of Clinical Sciences Cornell College of Veterinary Medicine Cornell University Ithaca NY USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2020,12,13]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/00006534-198901000-00024"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/jnr.23023"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jss.2008.03.032"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.expneurol.2006.12.004"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.2478\/v10039-010-0020-9"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.prs.0000260232.43019.a0"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1179\/1743132814Y.0000000386"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/0010-4809(84)90031-4"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/0014-4886(82)90234-5"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1529-8027.2007.00142.x"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/micr.20685"},{"key":"e_1_2_9_13_1","volume-title":"Textbook of Veterinary Anatomy","author":"Dyce K. 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