{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T04:03:25Z","timestamp":1789185805514,"version":"build-2803163510"},"reference-count":44,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2021,1,6]],"date-time":"2021-01-06T00:00:00Z","timestamp":1609891200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000646","name":"Japan Society for the Promotion of Science London","doi-asserted-by":"publisher","award":["16H03207"],"award-info":[{"award-number":["16H03207"]}],"id":[{"id":"10.13039\/501100000646","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000646","name":"Japan Society for the Promotion of Science London","doi-asserted-by":"publisher","award":["18K17691"],"award-info":[{"award-number":["18K17691"]}],"id":[{"id":"10.13039\/501100000646","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000646","name":"Japan Society for the Promotion of Science London","doi-asserted-by":"publisher","award":["20K11194"],"award-info":[{"award-number":["20K11194"]}],"id":[{"id":"10.13039\/501100000646","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Brain and Behavior"],"published-print":{"date-parts":[[2021,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Spontaneous oscillations in the somatosensory cortex, especially of the alpha (8\u00a0\u2212\u00a014\u00a0Hz) and gamma (60\u00a0\u2212\u00a080\u00a0Hz) frequencies, affect tactile perception; moreover, these oscillations can be selectively modulated by frequency\u2010matched transcranial alternating current stimulation (tACS) on the basis of ongoing oscillatory brain activity. To examine whether tACS can actually improve tactile perception via alpha and gamma modulation, we measured the effects of 10\u2010Hz and 70\u2010Hz tACS (\u03b1\u2010 and \u03b3\u2010tACS) on the left somatosensory cortex on right\u2010finger tactile spatial orientation discrimination, and the associations between performance changes and individual alpha and gamma activities.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Fifteen neurologically healthy subjects were recruited into this study. Electroencephalography (EEG) was performed before the first day, to assess the normal alpha\u2010 and gamma\u2010activity levels. A grating orientation discrimination task was performed before and during 10\u2010Hz and 70\u2010Hz tACS.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The 10\u2010Hz tACS protocol decreased the grating orientation discrimination threshold, primarily in subjects with low alpha event\u2010related synchronization (ERS). In contrast, the 70\u2010Hz tACS had no effect on the grating orientation discrimination threshold.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>This study showed that 10\u2010Hz tACS can improve tactile orientation discrimination in subjects with low alpha activity. Alpha\u2010frequency tACS may help identify the contributions of these oscillations to other neurophysiological and pathological processes.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/brb3.2019","type":"journal-article","created":{"date-parts":[[2021,1,7]],"date-time":"2021-01-07T23:39:31Z","timestamp":1610062771000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":20,"title":["\u03b1\u2010tACS over the somatosensory cortex enhances tactile spatial discrimination in healthy subjects with low alpha activity"],"prefix":"10.1002","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6007-2434","authenticated-orcid":false,"given":"Kei","family":"Saito","sequence":"first","affiliation":[{"name":"Department of Physical Therapy Niigata University of Health and Welfare Niigata Japan"},{"name":"Institute for Human Movement and Medical Sciences Niigata University of Health and Welfare Niigata 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