{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T15:01:43Z","timestamp":1772118103169,"version":"3.50.1"},"reference-count":51,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2021,1,13]],"date-time":"2021-01-13T00:00:00Z","timestamp":1610496000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Brain and Behavior"],"published-print":{"date-parts":[[2021,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>The aim of this study is to identify the association between Attention Deficit Hyperactivity Disorder (ADHD) proneness and aggressive propensity in adolescents.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A quantitative, large\u2010scale, cross\u2010sectional study was performed from April to May 2016 in Korea. The survey questionnaire included overall health behaviors, as well as scales for assessing ADHD proneness (revised short form of the Conners\u2010Wells Adolescent Self\u2010Report Scale; CASS[S]) and aggressive behavior (Buss\u2010Perry Aggression Questionnaire; BPAQ) in adolescents. Area under the receiver operator characteristic (AUROC) curves was constructed to determine the cut\u2010off value of total aggression score for discriminating ADHD proneness.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A total of 2,432 students participated in the survey, and 1,872 of them completed the questionnaire, indicating a response rate of 77.0%. Based on CASS(S), 33 (1.8%) subjects were classified as the ADHD group. AUROC curve analysis showed that a score of 68.5 points had higher sensitivity (83.3%) and specificity (69.4%) to discriminate ADHD proneness. ADHD proneness was significantly associated with higher aggression subdomain scores (physical, verbal, anger, and hostility). Especially, anger and hostility had a stronger relationship with ADHD proneness than did physical and verbal aggression. A multivariable analysis demonstrated that ADHD proneness was significantly related to body mass index in the top 10% of the study population, alcohol consumption, gastrointestinal trouble, daytime sleepiness, and total aggression score of 68.5 points or higher. Adolescents who had total aggression scores of 68.5 points or higher showed a 9.8\u2010fold (95% confidence interval [CI] 3.3\u201328.8) higher risk of ADHD compared with those who had scores less than 68.5 points.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Our results demonstrated that ADHD proneness was significantly associated with aggression propensity. In particular, anger and hostility were more closely associated with ADHD proneness than were other aggression subdomains.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/brb3.2030","type":"journal-article","created":{"date-parts":[[2021,1,15]],"date-time":"2021-01-15T09:33:01Z","timestamp":1610703181000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Association between attention deficit hyperactivity disorder and aggression subscales in adolescents"],"prefix":"10.1002","volume":"11","author":[{"given":"Hee Jeong","family":"Yoo","sequence":"first","affiliation":[{"name":"College of Pharmacy and Graduate School of Pharmaceutical Sciences Ewha Womans University Seoul Republic of Korea"},{"name":"Department of Pharmacy National Medical Center Seoul Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ji Min","family":"Han","sequence":"additional","affiliation":[{"name":"College of Pharmacy Chungbuk National University Cheongju Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kitai","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Communication Honam University Gwangju Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gonjin","family":"Song","sequence":"additional","affiliation":[{"name":"College of Pharmacy and Graduate School of Pharmaceutical Sciences Ewha Womans University Seoul Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeong","family":"Yee","sequence":"additional","affiliation":[{"name":"College of Pharmacy and Graduate School of Pharmaceutical Sciences Ewha Womans University Seoul Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jee Eun","family":"Chung","sequence":"additional","affiliation":[{"name":"College of Pharmacy, Institute of Pharmaceutical Science and Technology Hanyang University Ansan Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kyung Eun","family":"Lee","sequence":"additional","affiliation":[{"name":"College of Pharmacy Chungbuk National University Cheongju Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0278-2563","authenticated-orcid":false,"given":"Hye Sun","family":"Gwak","sequence":"additional","affiliation":[{"name":"College of Pharmacy and Graduate School of Pharmaceutical Sciences Ewha Womans University Seoul Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,1,13]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00911314"},{"key":"e_1_2_9_3_1","volume-title":"Attention deficit hyperactivity disorder: A handbook for diagnosis and treatment","author":"Barkley R.","year":"2014"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00787-018-1169-1"},{"key":"e_1_2_9_5_1","first-page":"564","article-title":"Comorbidity of attention deficit hyperactivity disorder with conduct, depressive, anxiety, and other disorders","volume":"5","author":"Biederman J.","year":"1991","journal-title":"American Journal of Psychiatry"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10964-013-9937-1"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1037\/0022-3514.63.3.452"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/00004583-199608000-00008"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12887-019-1479-6"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1080\/10408390701540124"},{"key":"e_1_2_9_11_1","doi-asserted-by":"crossref","first-page":"504","DOI":"10.1093\/sleep\/29.4.504","article-title":"Sleep and alertness in children with attention\u2010deficit\/hyperactivity disorder: A systematic review of the literature","volume":"29","author":"Cortese S.","year":"2006","journal-title":"Sleep"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1177\/000992280304200906"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1080\/10413200600830257"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1080\/15374416.2017.1417860"},{"key":"e_1_2_9_15_1","volume-title":"The Development and Treatment of Childhood Aggression","author":"Dodge K. 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