{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,18]],"date-time":"2026-10-18T15:02:26Z","timestamp":1792335746774,"version":"4.4.0"},"reference-count":47,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2021,7,28]],"date-time":"2021-07-28T00:00:00Z","timestamp":1627430400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Brain and Behavior"],"published-print":{"date-parts":[[2021,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Anorexia nervosa (AN) is a severe psychiatric illness with alarming mortality rates. Nevertheless, despite former and recent research results, the etiology of AN is still poorly understood. Of particular interest is that, despite exaggerated response control and increased perfectionism scores, patients with AN seem not to perform better that those unaffected in tasks that require inhibitory control. One reason might be aberrant processing of errors. The objective of our study was thus to obtain further insight into the pathopsychology of AN. We were particularly interested in neuronal and autonomic responses during error processing and their association with behavior.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We analyzed 16 acute patients suffering from restrictive type AN and 21 healthy controls using functional magnetic resonance imaging (fMRI) with simultaneous physiological recordings during a Go\/Nogo response inhibition task. Data were corrected for noise due to cardiac and respiratory influence.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Patients and controls had similarly successful response inhibition in Nogo trials. However, in failed Nogo trials, controls had significantly greater skin conductance responses (SCR) than in correct Nogo trials. Patients did not exhibit elevated SCR to errors. Furthermore, we found significantly increased neuronal responses, especially in the amygdala and hippocampus, in controls compared to patients during error trials. We also found significant positive correlations in controls but not in patients between Nogo performance and activation in the salience network core regions after errors.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Acute restrictive type AN patients seem to lack neuronal and autonomic responses to errors that might impede a flexible behavior adaption.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/brb3.2235","type":"journal-article","created":{"date-parts":[[2021,7,28]],"date-time":"2021-07-28T04:53:03Z","timestamp":1627447983000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Attenuated neuronal and autonomic responses during error processing in anorexia nervosa"],"prefix":"10.1002","volume":"11","author":[{"given":"Stefanie","family":"Suttkus","sequence":"first","affiliation":[{"name":"Lab for Autonomic Neuroscience Imaging and Cognition (LANIC) Department of Psychosomatic Medicine and Psychotherapy Jena University  Jena Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andy","family":"Schumann","sequence":"additional","affiliation":[{"name":"Lab for Autonomic Neuroscience Imaging and Cognition (LANIC) Department of Psychosomatic Medicine and Psychotherapy Jena University  Jena Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Feliberto","family":"De la Cruz","sequence":"additional","affiliation":[{"name":"Lab for Autonomic Neuroscience Imaging and Cognition (LANIC) Department of Psychosomatic Medicine and Psychotherapy Jena University  Jena Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karl\u2010J\u00fcrgen","family":"B\u00e4r","sequence":"additional","affiliation":[{"name":"Lab for Autonomic Neuroscience Imaging and Cognition (LANIC) Department of Psychosomatic Medicine and Psychotherapy Jena University  Jena Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,7,28]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1001\/archgenpsychiatry.2011.74"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2007.07.007"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpsycho.2010.01.011"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pscychresns.2015.12.008"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neubiorev.2016.08.022"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.psychres.2017.06.073"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.2517\u20106161.1995.tb02031.x"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2007.11.059"},{"key":"e_1_2_7_10_1","volume-title":"Functional neuroimaging of executive functions","author":"Braver T. 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