{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T15:02:12Z","timestamp":1772118132552,"version":"3.50.1"},"reference-count":10,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2021,6,4]],"date-time":"2021-06-04T00:00:00Z","timestamp":1622764800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Brain and Behavior"],"published-print":{"date-parts":[[2021,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Covid\u201019 has caused many complications for both the infected and those in need of medical care. This may be due to infection\u2010related prognosis worsening or the patients\u2019 avoidance of referring to the hospital for fear of contracting the infection. The decline of acute referral to the ER of many significant conditions with severe results on both the well\u2010being and life\u2010expectancy is a serious concern. To address these concerns, we designed this study to evaluate the recent pandemic's impact on \u201cin\u2010hospital mortality\u201d caused by neurological disorders pre and postpandemic.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods and material<\/jats:title>\n                    <jats:p>The inclusion criteria were any acute neurological condition and the consent of the patients eligible for our study. The definitions of all assessed conditions and the comorbidities are ICD\u201010 based. Hypertension and diabetes mellitus, due to their high prevalence, were evaluated separately from other internal comorbidities. The total number of the enrolled patients was 1742, 671 of whom had been during the COVID\u201019 pandemic, and 1071 had attended the ER during the prepandemic era.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The overall mortality was significantly higher during the pandemic, and the covid infected had suffered higher mortality rates. (\n                      <jats:italic>p<\/jats:italic>\n                      \u2010value\u00a0&lt;\u00a00.05)\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>During the pandemic, those with minor strokes and other nonlife\u2010threatening ailments had avoided hospital care leading to a significantly higher rate of critical conditions. Increased incidence of strokes and ICHs during the pandemic, too, caused significant increased in\u2010hospital mortality.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/brb3.2246","type":"journal-article","created":{"date-parts":[[2021,6,4]],"date-time":"2021-06-04T18:15:18Z","timestamp":1622830518000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Effects of the covid\u201019 pandemic on neurological diseases"],"prefix":"10.1002","volume":"11","author":[{"given":"Nahid Abbasi","family":"Khoshsirat","sequence":"first","affiliation":[{"name":"Rajaee Hospital Department of Neurology and Neurological Diseases Alborz University of Medical Sciences  Karaj Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mostafa","family":"Qorbani","sequence":"additional","affiliation":[{"name":"Non\u2010communicable Diseases Research Center Alborz University of Medical Sciences  Karaj Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ali Mokhtari","family":"Farivar","sequence":"additional","affiliation":[{"name":"Madani Hospital Department of Medical Emergencies Alborz University of Medical Sciences  Karaj Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sahar","family":"Mohammadpoor Nami","sequence":"additional","affiliation":[{"name":"Student Research Committee Alborz University of Medical Sciences  Karaj Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nami","family":"Mohammadian Khonsari","sequence":"additional","affiliation":[{"name":"Non\u2010communicable Diseases Research Center Alborz University of Medical Sciences  Karaj Iran"},{"name":"Student Research Committee Alborz University of Medical Sciences  Karaj Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,6,4]]},"reference":[{"key":"e_1_2_13_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00417-020-04858-7"},{"key":"e_1_2_13_3_1","first-page":"69","article-title":"Impact of the COVID\u201019 Pandemic on Emergency Department Visits\u2014United States, January 1, 2019\u2013May 30, 2020","author":"Hartnett K. P.","year":"2020","journal-title":"MMWR Morbidity and Mortality Weekly Report"},{"key":"e_1_2_13_4_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2020.24984"},{"key":"e_1_2_13_5_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamahealthforum.2020.1172"},{"key":"e_1_2_13_6_1","volume-title":"ICD\u201010: International statistical classification of diseases and related health problems: Tenth revision","author":"World Health O","year":"2004"},{"key":"e_1_2_13_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ahj.2020.10.074"},{"key":"e_1_2_13_8_1","doi-asserted-by":"publisher","DOI":"10.2478\/raon\u20102020\u20100048"},{"key":"e_1_2_13_9_1","first-page":"51","article-title":"Iranian mental health during the COVID\u201019 epidemic","author":"Zandifar A.","year":"2020","journal-title":"Asian Journal of Psychiatry"},{"key":"e_1_2_13_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/pcn.13098"},{"issue":"4","key":"e_1_2_13_11_1","first-page":"355","article-title":"Prevalence and associated factors of posttraumatic stress symptoms and stigma among health care workers in contact with COVID\u201019 patients","volume":"15","author":"Zandifar A.","year":"2020","journal-title":"Iranian Journal of Psychiatry"}],"container-title":["Brain and Behavior"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/brb3.2246","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/brb3.2246","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/brb3.2246","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,17]],"date-time":"2023-08-17T23:44:28Z","timestamp":1692315868000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/brb3.2246"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,6,4]]},"references-count":10,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2021,8]]}},"alternative-id":["10.1002\/brb3.2246"],"URL":"https:\/\/doi.org\/10.1002\/brb3.2246","archive":["Portico"],"relation":{"has-review":[{"id-type":"doi","id":"10.1002\/BRB3.2246\/v1\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1002\/BRB3.2246\/v2\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1002\/BRB3.2246\/v1\/review1","asserted-by":"object"},{"id-type":"doi","id":"10.1002\/BRB3.2246\/v2\/response1","asserted-by":"object"}]},"ISSN":["2162-3279","2162-3279"],"issn-type":[{"value":"2162-3279","type":"print"},{"value":"2162-3279","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,6,4]]},"assertion":[{"value":"2021-01-05","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-05-25","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-06-04","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e2246"}}