{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T14:59:20Z","timestamp":1772117960213,"version":"3.50.1"},"reference-count":15,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2021,10,17]],"date-time":"2021-10-17T00:00:00Z","timestamp":1634428800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Brain and Behavior"],"published-print":{"date-parts":[[2021,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>This report describes the successful treatment of two patients with trigeminal neuropathy by using gasserian ganglion stimulation.<\/jats:p>\n                  <jats:p>\n                    <jats:bold>Case reports<\/jats:bold>\n                    : The first case report deals with a 53\u2010year\u2010old woman suffering from right\u2010sided facial pain after a gamma knife lesion for schwannoma of the right inner ear. For 9 years, several interventions with the aim of relieving the pain were unsuccessful; in fact, they had aggravated the symptoms. A trial with a neurostimulator at the level of the Gasser ganglion had an immediately positive effect on her score for facial pain, which decreased from 7.3 to 0 on a visual analog scale, assessed during a period of 2\u00a0months. Additionally, the patient had weaned off all her medication by the end of the period. The second case report describes a 64\u2010year\u2010old man suffering from trigeminal neuropathy, which mainly manifested itself as an itch. For a period of 15 years, neither medication nor several interventions were effective. A trial with an electrode at the level of the Gasser ganglion reduced his pain score from 7.0 to 1.5 on a visual analog scale, assessed during a period of three months. His medication could be limited to pregabalin 150\u00a0mg bidaily. In contrast, prior to the implantation, his oral medication consisted of pregabalin 75\u00a0mg up to five times a day.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Conclusion<\/jats:bold>\n                    : These case reports show that stimulation of the gasserian ganglion is a successful, minimally invasive, and non\u2010destructive treatment in refractory trigeminal neuropathy and should be considered earlier in the treatment algorithm of trigeminal neuropathy.\n                  <\/jats:p>","DOI":"10.1002\/brb3.2379","type":"journal-article","created":{"date-parts":[[2021,10,21]],"date-time":"2021-10-21T00:47:11Z","timestamp":1634777231000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Trigeminal neuropathy: Two case reports of gasserian ganglion stimulation"],"prefix":"10.1002","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6568-5774","authenticated-orcid":false,"given":"Yannick","family":"Logghe","sequence":"first","affiliation":[{"name":"Multidisciplinary Pain Center AZ Nikolaas  Sint\u2010Niklaas Belgium"},{"name":"Department of Anesthesiology AZ Nikolaas  Sint\u2010Niklaas Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Iris","family":"Smet","sequence":"additional","affiliation":[{"name":"Multidisciplinary Pain Center AZ Nikolaas  Sint\u2010Niklaas Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ali","family":"Jerjir","sequence":"additional","affiliation":[{"name":"Multidisciplinary Pain Center AZ Nikolaas  Sint\u2010Niklaas Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter","family":"Verelst","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology AZ Nikolaas  Sint\u2010Niklaas Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marieke","family":"Devos","sequence":"additional","affiliation":[{"name":"Multidisciplinary Pain Center AZ Nikolaas  Sint\u2010Niklaas Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jean\u2010Pierre","family":"Van Buyten","sequence":"additional","affiliation":[{"name":"Multidisciplinary Pain Center AZ Nikolaas  Sint\u2010Niklaas Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,10,17]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.36076\/ppj\/2019.22.447"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1227\/01.NEU.0000088806.11659.D8"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/ner.12215"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2015.02.028"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.11607\/jop.1154"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcms.2016.10.014"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/978\u20103\u2010211\u201033081\u20104_11"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1177\/0333102417738202"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1055\/s\u20102008\u20101041389"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.3171\/jns.1974.40.2.0143"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.3171\/jns.1997.86.2.0197"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1159\/000434658"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525\u20101403.2009.00222.x"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pain.2007.04.017"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2018.09.005"}],"container-title":["Brain 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