{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T15:00:39Z","timestamp":1772118039659,"version":"3.50.1"},"reference-count":31,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2022,5,5]],"date-time":"2022-05-05T00:00:00Z","timestamp":1651708800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Brain and Behavior"],"published-print":{"date-parts":[[2022,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>The burden of disease for persons with multiple sclerosis (MS) and society is changing due to new treatments. Knowledge about the total need for care is necessary in relation to changing needs and new service models.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>The aim of this study was to describe the contact patterns for MS patients, calculate costs in health care, and create meaningful subgroups to analyze contact patterns.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>All patients diagnosed with MS at Ryhov Hospital were included. All contacts in the region from January 1, 2018, until September 30, 2019, were retrieved from the hospital administrative system. Data about age, sex, contacts, and diagnosis were registered. The cost was calculated using case costing, and costs for prescriptions were calculated from medical files.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      During the 21\u2010month period, patients (\n                      <jats:italic>n<\/jats:italic>\n                      = 305) had 9628 contacts and 7471 physical visits, with a total cost of $7,766,109. Seventeen percent of the patients accounted for 48% of the visits. The median annual cost was $7386 in the group with 10 or fewer visits, compared to $22,491 in patients with more than 50 visits.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>There are considerable differences in the utilization of care and cost between patients with MS in an unselected population, meaning that the care needs to be better customized to each patient's demands.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/brb3.2582","type":"journal-article","created":{"date-parts":[[2022,5,5]],"date-time":"2022-05-05T11:09:23Z","timestamp":1651748963000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Contact patterns and costs of multiple sclerosis in the Swedish healthcare system\u2014A population\u2010based quantitative study"],"prefix":"10.1002","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5357-3767","authenticated-orcid":false,"given":"Jonas","family":"Lind","sequence":"first","affiliation":[{"name":"Section of Neurology Department of Internal Medicine County Hospital Ryhov  J\u00f6nk\u00f6ping Sweden"},{"name":"Division of Neurobiology Department of Biomedical and Clinical Sciences Link\u00f6ping University Link\u00f6ping  Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9049-6254","authenticated-orcid":false,"given":"Sofia","family":"Persson","sequence":"additional","affiliation":[{"name":"Department of Public Health and Health Care Region J\u00f6nk\u00f6ping County  J\u00f6nk\u00f6ping Sweden"},{"name":"J\u00f6nk\u00f6ping Academy for Improvement of Health and Welfare School of Health and Welfare J\u00f6nk\u00f6ping University  J\u00f6nk\u00f6ping Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9644-333X","authenticated-orcid":false,"given":"Jonatan","family":"Vincent","sequence":"additional","affiliation":[{"name":"Department of Public Health and Health Care Region J\u00f6nk\u00f6ping County  J\u00f6nk\u00f6ping Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0123-6392","authenticated-orcid":false,"given":"Bertil","family":"Lindenfalk","sequence":"additional","affiliation":[{"name":"J\u00f6nk\u00f6ping Academy for Improvement of Health and Welfare School of Health and Welfare J\u00f6nk\u00f6ping University  J\u00f6nk\u00f6ping Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7399-622X","authenticated-orcid":false,"given":"Brant J.","family":"Oliver","sequence":"additional","affiliation":[{"name":"Departments of Community and Family Medicine Psychiatry, and the Dartmouth Institute for Health Policy and Clinical Practice at the Geisel School of Medicine at Dartmouth Dartmouth College  Hanover New Hampshire USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3002-222X","authenticated-orcid":false,"suffix":"III","given":"Andrew D.","family":"Smith","sequence":"additional","affiliation":[{"name":"Multiple Sclerosis Center Dartmouth\u2010Hitchcock Medical Center and Geisel School of Medicine Dartmouth College  Lebanon New Hampshire USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1176-8173","authenticated-orcid":false,"given":"Boel","family":"Andersson G\u00e4re","sequence":"additional","affiliation":[{"name":"J\u00f6nk\u00f6ping Academy for Improvement of Health and Welfare School of Health and Welfare J\u00f6nk\u00f6ping University J\u00f6nk\u00f6ping and Futurum Region J\u00f6nk\u00f6ping County  Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2022,5,5]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.3111\/13696998.2013.778268"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.k3617"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jclinepi.2016.01.006"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/ene.15030"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jocn.2017.06.005"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12913-015-1144-1"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jns.2014.01.020"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2016-014650"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.2147\/PROM.S44694"},{"key":"e_1_2_9_11_1","volume-title":"Kostnad per patient (Swedish)","author":"Fitger P.","year":"2015"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/lrh2.10212"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13311-017-0566-3"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.2003.029660"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1097\/MLR.0000000000001438"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-1331.2005.01193.x"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1177\/1352458517694432"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1177\/1352458514564491"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.3310\/hta21520"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40120-019-00172-5"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2020-037578"},{"issue":"6","key":"e_1_2_9_22_1","first-page":"s151","article-title":"Economic burden of multiple sclerosis and the role of managed sare organizations in multiple sclerosis management","volume":"22","author":"Owens G. M.","year":"2016","journal-title":"American Journal of Managed Care"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/joim.12204"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000003331"},{"key":"e_1_2_9_25_1","unstructured":"(SCB) SS. (n.d.).Population statistics 2019.https:\/\/www.scb.se\/en\/finding\u2010statistics\/statistics\u2010by\u2010subject\u2010area\/population\/population\u2010composition\/population\u2010statistics\/"},{"key":"e_1_2_9_26_1","unstructured":"Smith A. Varieur J. Bryan E. C. &Oliver B.(2020 February 27\u201329).Development of a coproduction model of comprehensive multiple sclerosis care [Conference presentation].Poster presented at the Americas Committee for Treatment and Research in Multiple Sclerosis Virtual Meeting."},{"key":"e_1_2_9_27_1","doi-asserted-by":"publisher","DOI":"10.1080\/13548506.2016.1164321"},{"key":"e_1_2_9_28_1","doi-asserted-by":"publisher","DOI":"10.1111\/hex.12955"},{"key":"e_1_2_9_29_1","unstructured":"Swedish Neuro Registries. (n.d.)https:\/\/msvap.carmona.se\/"},{"key":"e_1_2_9_30_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurpub\/cku025"},{"key":"e_1_2_9_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(18)30481-1"},{"key":"e_1_2_9_32_1","doi-asserted-by":"publisher","DOI":"10.1080\/14719037.2014.930505"}],"container-title":["Brain and Behavior"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/brb3.2582","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/brb3.2582","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/brb3.2582","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,16]],"date-time":"2023-08-16T19:29:43Z","timestamp":1692214183000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/brb3.2582"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,5,5]]},"references-count":31,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2022,6]]}},"alternative-id":["10.1002\/brb3.2582"],"URL":"https:\/\/doi.org\/10.1002\/brb3.2582","archive":["Portico"],"relation":{"has-review":[{"id-type":"doi","id":"10.1002\/BRB3.2582\/v2\/response1","asserted-by":"object"},{"id-type":"doi","id":"10.1002\/BRB3.2582\/v2\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1002\/BRB3.2582\/v1\/decision1","asserted-by":"object"}]},"ISSN":["2162-3279","2162-3279"],"issn-type":[{"value":"2162-3279","type":"print"},{"value":"2162-3279","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,5,5]]},"assertion":[{"value":"2022-02-23","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-03-25","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-05-05","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e2582"}}