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In recent years, the study of inflammatory processes in AD has gained special attention. Continued stress causes the reactivity of the hypothalamic\u2013pituitary\u2013adrenal (HPA) axis, the alteration of the intestinal microbiota and the consequent release of pro\u2010inflammatory cytokines, affecting the sensitivity to stress and the similar behavior of anxiety.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Method<\/jats:title>\n                    <jats:p>The aim of the present study was to evaluate the interrelationships between measures of proinflammatory cytokines and cortisol in patients with panic disorder (PD).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The main results of the correlation analysis revealed that the levels of pro\u2010inflammatory cytokines interleukin (IL)\u20101\u03b2, IL\u201012, and tumor necrosis factor gamma were negatively correlated with cortisol scores (area under the curve with respect to the ground).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>These results suggest that the inflammatory response is associated with the reactivity of the HPA axis in patients with PD and may influence the maintenance of anxiety behavior.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/brb3.2624","type":"journal-article","created":{"date-parts":[[2022,5,19]],"date-time":"2022-05-19T14:22:31Z","timestamp":1652970151000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Negative correlation between IL\u20101\u03b2, IL\u201012 and TNF\u2010\u03b3, and cortisol levels in patients with panic disorder"],"prefix":"10.1002","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1539-667X","authenticated-orcid":false,"given":"Ana Bel\u00e9n","family":"Fern\u00e1ndez\u2010Serrano","sequence":"first","affiliation":[{"name":"Health Sciences PhD program Universidad Cat\u00f3lica de Murcia UCAM  Murcia Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5832-4900","authenticated-orcid":false,"given":"Francisco Jos\u00e9","family":"Moya\u2010Faz","sequence":"additional","affiliation":[{"name":"Chair of Psychogeriatrics Department of Health Sciences Universidad Cat\u00f3lica de Murcia UCAM  Murcia Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cesar Augusto","family":"Giner Alegr\u00eda","sequence":"additional","affiliation":[{"name":"Department of Legal and Business Sciences Universidad Cat\u00f3lica de Murcia UCAM  Murcia Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3312-861X","authenticated-orcid":false,"given":"Juan Carlos","family":"Fern\u00e1ndez Rodr\u00edguez","sequence":"additional","affiliation":[{"name":"Director of the Psychology Department Universidad Internacional de la Rioja  Logrono Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,5,19]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/jep.13386"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/spc3.12309"},{"key":"e_1_2_7_4_1","first-page":"771","article-title":"La versi\u00f3n espa\u00f1ola del SF\u201036 Health Survey (Cuestionario de Salud SF\u201036): Un instrumento para la medida de los resultados cl\u00ednicos","volume":"104","author":"Alonso J.","year":"1995","journal-title":"Medicina Cl\u00ednica"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0895-4356(98)00100-0"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.intimp.2018.11.037"},{"key":"e_1_2_7_7_1","unstructured":"Angeloni S. 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