{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T15:02:17Z","timestamp":1772118137496,"version":"3.50.1"},"reference-count":47,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2022,10,28]],"date-time":"2022-10-28T00:00:00Z","timestamp":1666915200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Brain and Behavior"],"published-print":{"date-parts":[[2022,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Seizures and delirium tremens (DTs) are recognized as severe alcohol\u2010withdrawal symptoms. Prolonged admission and serious complications associated with alcohol withdrawal are responsible for increased costs and use of medical and social resources. This study investigated the predictive value of quantitative electroencephalography (QEEG) for developing alcohol\u2010related DTs after alcohol\u2010withdrawal seizure (AWS).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      We compared differences in QEEG in patients after AWS (\n                      <jats:italic>n<\/jats:italic>\n                      = 13). QEEG was performed in the intensive care unit within 48 h of admission, including in age\u2010 and sex\u2010matched healthy controls. We also investigated the prognostic value of QEEG for the development of alcohol DTs after AWS in a retrospective, case\u2012control study. The spectral power of each band frequency and the ratio of the theta to alpha band (TAR) in the electroencephalogram were analyzed using iSyncBrain\n                      <jats:sup>\u00ae<\/jats:sup>\n                      (iMediSync, Inc., Korea).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The beta frequency and the alpha frequency band power were significantly higher and lower, respectively, in patients than in age\u2010 and sex\u2010matched healthy controls. In AWS patients with DTs, the relative beta\u20103 power was lower, particularly in the left frontal area, and the TAR was significantly higher in the central channel than in those without DTs.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Quantitative EEG showed neuronal excitability and decreased cognitive activities characteristic of AWS associated with alcohol\u2010withdrawal state, and we demonstrated that quantitative EEG might be a helpful tool for detecting patients at a high risk of developing DTs during an alcohol\u2010dependence period.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/brb3.2804","type":"journal-article","created":{"date-parts":[[2022,10,28]],"date-time":"2022-10-28T14:20:39Z","timestamp":1666966839000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Quantitative electroencephalographic analysis of delirium tremens development following alcohol\u2010withdrawal seizure based on a small number of male cases"],"prefix":"10.1002","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2203-2698","authenticated-orcid":false,"given":"Jee\u2010Eun","family":"Yoon","sequence":"first","affiliation":[{"name":"Department of Neurology Uijeongbu Eulji Medical Center, Eulji University School of Medicine  Uijeongbu Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Heejung","family":"Mo","sequence":"additional","affiliation":[{"name":"Department of Neurology, Dongtan Sacred Heart Hospital Hallym University College of Medicine  Hwaseong Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dong Wook","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Neurology School of Medicine, Konkuk University  Seoul Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8979-6521","authenticated-orcid":false,"given":"Hee\u2010Jin","family":"Im","sequence":"additional","affiliation":[{"name":"Department of Neurology, Dongtan Sacred Heart Hospital Hallym University College of Medicine  Hwaseong Republic of 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