{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T18:57:34Z","timestamp":1790621854385,"version":"4.1.0"},"reference-count":72,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2014,9,21]],"date-time":"2014-09-21T00:00:00Z","timestamp":1411257600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"funder":[{"DOI":"10.13039\/100006221","name":"United States - Israel Binational Science Foundation","doi-asserted-by":"publisher","award":["2009053"],"award-info":[{"award-number":["2009053"]}],"id":[{"id":"10.13039\/100006221","id-type":"DOI","asserted-by":"publisher"}]},{"name":"University of Cincinnati Research Grant","award":["0001253"],"award-info":[{"award-number":["0001253"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Brain and Behavior"],"published-print":{"date-parts":[[2014,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>\n                      Dyslexia is characterized by slow, inaccurate reading. Previous studies have shown that the Reading Acceleration Program (RAP) improves reading speed and accuracy in children and adults with dyslexia and in typical readers across different orthographies. However, the effect of the RAP on the neural circuitry of reading has not been established. In the current study, we examined the effect of the RAP training on regions of interest in the neural circuitry for reading using a lexical decision task during\n                      <jats:styled-content style=\"fixed-case\">fMRI<\/jats:styled-content>\n                      in children with reading difficulties and typical readers.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      Children (8\u201312\u00a0years old) with reading difficulties and typical readers were studied before and after 4\u00a0weeks of training with the\n                      <jats:styled-content style=\"fixed-case\">RAP<\/jats:styled-content>\n                      in both groups.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>In addition to improvements in oral and silent contextual reading speed, training\u2010related gains were associated with increased activation of the left hemisphere in both children with reading difficulties and typical readers. However, only children with reading difficulties showed improvements in reading comprehension, which were associated with significant increases in right frontal lobe activation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>\n                      Our results demonstrate differential effects of the\n                      <jats:styled-content style=\"fixed-case\">RAP<\/jats:styled-content>\n                      on neural circuits supporting reading in both children with reading difficulties and typical readers and suggest that the intervention may stimulate use of typical neural circuits for reading and engage compensatory pathways to support reading in the developing brain of children with reading difficulties.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/brb3.281","type":"journal-article","created":{"date-parts":[[2014,9,22]],"date-time":"2014-09-22T02:09:59Z","timestamp":1411351799000},"page":"886-902","source":"Crossref","is-referenced-by-count":55,"title":["Reading acceleration training changes brain circuitry in children with reading difficulties"],"prefix":"10.1002","volume":"4","author":[{"given":"Tzipi","family":"Horowitz\u2010Kraus","sequence":"first","affiliation":[{"name":"Pediatric Neuroimaging Research Consortium Cincinnati Children's Hospital Medical Center Cincinnati Ohio"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer J.","family":"Vannest","sequence":"additional","affiliation":[{"name":"Pediatric Neuroimaging Research Consortium Cincinnati Children's Hospital Medical Center Cincinnati Ohio"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Darren","family":"Kadis","sequence":"additional","affiliation":[{"name":"Pediatric Neuroimaging Research Consortium Cincinnati Children's Hospital Medical Center Cincinnati Ohio"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicole","family":"Cicchino","sequence":"additional","affiliation":[{"name":"Pediatric Neuroimaging Research Consortium Cincinnati Children's Hospital Medical Center Cincinnati Ohio"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yingying Y.","family":"Wang","sequence":"additional","affiliation":[{"name":"Pediatric Neuroimaging Research Consortium Cincinnati Children's Hospital Medical Center Cincinnati Ohio"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Scott K.","family":"Holland","sequence":"additional","affiliation":[{"name":"Pediatric Neuroimaging Research Consortium Cincinnati Children's Hospital Medical Center Cincinnati Ohio"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2014,9,21]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cub.2013.02.051"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/hbm.21384"},{"key":"e_1_2_8_4_1","first-page":"383","volume-title":"Dyslexia, fluency, and the brain","author":"Berninger V. 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