{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,7]],"date-time":"2023-10-07T07:13:06Z","timestamp":1696662786372},"reference-count":14,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2014,9,11]],"date-time":"2014-09-11T00:00:00Z","timestamp":1410393600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"funder":[{"name":"JSPS KAKENHI","award":["26461828"],"award-info":[{"award-number":["26461828"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Brain and Behavior"],"published-print":{"date-parts":[[2014,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>We report the clinical application of intravoxel incoherent motion (<jats:styled-content style=\"fixed-case\">IVIM<\/jats:styled-content>) magnetic resonance (<jats:styled-content style=\"fixed-case\">MR<\/jats:styled-content>) imaging to diagnose a case of mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke\u2010like episodes (<jats:styled-content style=\"fixed-case\">MELAS<\/jats:styled-content>) in the acute phase.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>On <jats:styled-content style=\"fixed-case\">IVIM MR<\/jats:styled-content> Images of this patient, higher perfusion (f) and diffusion (D) values in the left occipital and temporal lobes were found compared to the contralateral areas.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>These findings imply a breakdown of autoregulation with hyperperfusion and vasogenic edema during the acute phase of <jats:styled-content style=\"fixed-case\">MELAS<\/jats:styled-content>, as described in previous reports. <jats:styled-content style=\"fixed-case\">IVIM<\/jats:styled-content> imaging is a valuable, noninvasive tool that simultaneously quantifies perfusion and diffusion parameters.<\/jats:p><\/jats:sec>","DOI":"10.1002\/brb3.282","type":"journal-article","created":{"date-parts":[[2014,9,12]],"date-time":"2014-09-12T04:13:09Z","timestamp":1410495189000},"page":"798-800","source":"Crossref","is-referenced-by-count":0,"title":["Intravoxel incoherent motion magnetic resonance imaging findings in the acute phase of <scp>MELAS<\/scp>: a case report"],"prefix":"10.1002","volume":"4","author":[{"given":"Ryuji","family":"Uehara","sequence":"first","affiliation":[{"name":"Department of Clinical Radiology Graduate School of Medical Sciences Kyushu University 3\u20101\u20101, Maidashi Higashi\u2010ku Fukuoka 812\u20108582 Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Koji","family":"Yamashita","sequence":"additional","affiliation":[{"name":"Department of Clinical Radiology Graduate School of Medical Sciences Kyushu University 3\u20101\u20101, Maidashi Higashi\u2010ku Fukuoka 812\u20108582 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