{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T17:53:02Z","timestamp":1787161982592,"version":"build-2736575974"},"reference-count":36,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2022,12,8]],"date-time":"2022-12-08T00:00:00Z","timestamp":1670457600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Brain and Behavior"],"published-print":{"date-parts":[[2023,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>This study investigated the factors associated with the high susceptibility of perimenopausal women to depression.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A total of 66 perimenopausal women participated in this study. The Zung self\u2010rating depression scale (SDS) was used to evaluate the intensity of depressive symptoms. The modified Kupperman index (KI) was used to assess common perimenopausal symptoms. Psychosocial factors were assessed via the Eysenck Personality Questionnaire, attitudes toward menopause checklist, and metacognition questionnaire (MCQ). Levels of serum estradiol, testosterone, and progesterone were determined.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      There were statistically significant associations between SDS standard score and the KI scale score (\n                      <jats:italic>\u03b2<\/jats:italic>\n                      \u00a0=\u00a0.361,\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a0.001), years of education (\n                      <jats:italic>\u03b2<\/jats:italic>\n                      \u00a0=\u00a0\u2212.309,\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a0.005), and F3 cognitive self\u2010consciousness score of MCQ (\n                      <jats:italic>\u03b2<\/jats:italic>\n                      \u00a0=\u00a0\u2212.234,\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a0.032; adjusted\n                      <jats:italic>R<\/jats:italic>\n                      <jats:sup>2<\/jats:sup>\n                      \u00a0=\u00a0.264,\n                      <jats:italic>F<\/jats:italic>\n                      \u00a0=\u00a08.759,\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0&lt;\u00a0.001).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>High susceptibility to depression of perimenopausal women may be related to lower educational level, more severe perimenopausal symptoms, and altered metacognition.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/brb3.2826","type":"journal-article","created":{"date-parts":[[2022,12,8]],"date-time":"2022-12-08T09:33:48Z","timestamp":1670492028000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Factors associated with the high susceptibility to depression of women during the perimenopause"],"prefix":"10.1002","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2884-6652","authenticated-orcid":false,"given":"Hongying","family":"Han","sequence":"first","affiliation":[{"name":"Department of Psychiatry The Third Affiliated Hospital of Sun Yat\u2010sen University  Guangzhou Guangdong Province 510630 P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaowei","family":"Xia","sequence":"additional","affiliation":[{"name":"Department of Psychiatry The Third Affiliated Hospital of Sun Yat\u2010sen University  Guangzhou Guangdong Province 510630 P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huirong","family":"Zheng","sequence":"additional","affiliation":[{"name":"Guangdong Mental Health Center Guangdong Provincial People's hospital Guangdong Academy of Medical Sciences Affiliated School of Medicine of South China University of Technology  Guangzhou Guangdong Province 510080 P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhiyong","family":"Zhong","sequence":"additional","affiliation":[{"name":"Department of Psychiatry The Third Affiliated Hospital of Sun Yat\u2010sen University  Guangzhou Guangdong Province 510630 P. R. 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