{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,6]],"date-time":"2026-03-06T14:00:56Z","timestamp":1772805656075,"version":"3.50.1"},"reference-count":27,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2022,11,21]],"date-time":"2022-11-21T00:00:00Z","timestamp":1668988800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Brain and Behavior"],"published-print":{"date-parts":[[2022,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Both progressive supranuclear palsy (PSP) and multiple system atrophy (MSA) belong to atypical parkinsonian syndromes. It is important to differentiate these diseases accurately. We compared clinical outcomes and cognitive impairments between PSP and MSA.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Eighty\u2010five MSA parkinsonism type (MSA\u2010P) patients and 76 PSP patients participated in this research. The Montreal Cognitive Assessment (MoCA) and the mini\u2010mental state examination (MMSE) evaluated cognitive function.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>MSA\u2010P patients had a significantly higher incidence of dyskinesia, fall, urinary symptoms, and constipation, whereas patients with PSP had a higher incidence of tremor and salivation. MSA\u2010P patients had higher MMSE and MoCA scores than PSP patients. The MMSE score showed a diagnostic cut\u2010off score of 24.5 in PSP versus MSA\u2010P. The MoCA score showed a diagnostic cut\u2010off score of 20.5 in PSP versus MSA\u2010P.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>In conclusion, patients with PSP had differences in the clinical outcomes and cognitive impairments compared with MSA\u2010P patients. PSP patients had more severe cognitive deficits. The score of MMSE and MoCA could be used in distinguishing MSA\u2010P from PSP.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/brb3.2827","type":"journal-article","created":{"date-parts":[[2022,11,21]],"date-time":"2022-11-21T08:43:41Z","timestamp":1669020221000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Clinical outcomes and cognitive impairments between progressive supranuclear palsy and multiple system atrophy"],"prefix":"10.1002","volume":"12","author":[{"given":"Peifei","family":"Jia","sequence":"first","affiliation":[{"name":"Clinical College of Neurology, Neurosurgery and Neurorehabilitation Tianjin Medical University  Tianjin China"},{"name":"Department of Neurology The Second Affiliated Hospital of Baotou Medical College  Baotou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4741-3040","authenticated-orcid":false,"given":"Jinhong","family":"Zhang","sequence":"additional","affiliation":[{"name":"Clinical College of Neurology, Neurosurgery and Neurorehabilitation Tianjin Medical University  Tianjin China"},{"name":"Department of Neurology Cangzhou People's Hospital  Cangzhou Hebei China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiuyan","family":"Han","sequence":"additional","affiliation":[{"name":"Department of Neurology, Beijing Tiantan Hospital Capital Medical University  Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yong","family":"Ji","sequence":"additional","affiliation":[{"name":"Department of Neurology Tianjin Huanhu Hospital  Tianjin China"},{"name":"Department of Neurology, Beijing Tiantan Hospital, Capital Medical University China National Clinical Research Center for Neurological Diseases  Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2022,11,21]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11910-018-0819-5"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(18)30039-5"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/ene.12022"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(17)30157-6"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.22413"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/ene.13412"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1101\/cshperspect.a028035"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1101\/cshperspect.a033118"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/bs.irn.2019.10.004"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000324625.00404.15"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.38.7.1031"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0b013e3181a2e815"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awf080"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(12)70022-4"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.47.1.1"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/ane.12546"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awn065"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.autneu.2017.10.007"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.parkreldis.2020.10.039"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(99)04137-9"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.4103\/0028-3886.226459"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinph.2015.07.035"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.autneu.2017.11.002"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.2174\/1567205015666180507111958"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-444-53491-0.00019-5"},{"key":"e_1_2_8_27_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awh488"},{"key":"e_1_2_8_28_1","first-page":"1189","article-title":"Parkinsonian syndromes","volume":"19","author":"Williams D. 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