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Because psychophysiological alterations are a core diagnostic feature of PTSD and CPTSD, the aim of the current study was to examine potential distinctive patterns in cortical and cardiac responses to emotional words in adolescent and young adult patients with PTSD and CPTSD.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Method<\/jats:title>\n                    <jats:p>Event\u2010related potentials and heart rate responses were studied in 81 adolescent and young adult participants, of which 17 individuals were diagnosed with ICD\u201011 PTSD and 32 individuals with CPTSD, each after childhood sexual and\/or physical abuse. Thirty\u2010two individuals served as healthy controls. The paradigm consisted of a passive reading task with neutral, positive, physically threatening, and socially threatening words.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Differentiated early processing of emotional words was indicated by differences on P1 and left EPN components. Additionally, PTSD and CPTSD patients presented with specific patterns of heart rate responses to emotional words. In CPTSD patients, heart rate reactions to emotional words were more variable than in PTSD patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>These findings provide early evidence of differentiated cortical and cardiac response patterns in adolescent and young adult patients with CPTSD and PTSD, supporting a nosological distinction between PTSD and complex PTSD. However, due to small and unequal sample sizes, findings presented in the current study are preliminary and require future research.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/brb3.2904","type":"journal-article","created":{"date-parts":[[2023,2,7]],"date-time":"2023-02-07T09:43:42Z","timestamp":1675763022000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Differentiated processing of emotional cues in adolescents and young adults with ICD\u201011 PTSD and complex PTSD after child abuse"],"prefix":"10.1002","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3122-005X","authenticated-orcid":false,"given":"Benjamin","family":"Iffland","sequence":"first","affiliation":[{"name":"Department of Psychology Bielefeld University  Bielefeld Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rebekka","family":"Eilers","sequence":"additional","affiliation":[{"name":"Department of Psychology Catholic University Eichst\u00e4tt\u2010Ingolstadt  Eichst\u00e4tt Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rita","family":"Rosner","sequence":"additional","affiliation":[{"name":"Department of Psychology Catholic University Eichst\u00e4tt\u2010Ingolstadt  Eichst\u00e4tt Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Babette","family":"Renneberg","sequence":"additional","affiliation":[{"name":"Clinical Psychology and Psychotherapy Freie Universitaet Berlin  Berlin Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Regina","family":"Steil","sequence":"additional","affiliation":[{"name":"Department of Clinical Psychology and Psychotherapy, Institute of Psychology Goethe University Frankfurt  Frankfurt Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Frank","family":"Neuner","sequence":"additional","affiliation":[{"name":"Department of Psychology Bielefeld University  Bielefeld Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,2,7]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469\u20108986.2009.00940.x"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopsych.2010.05.015"},{"key":"e_1_2_9_4_1","unstructured":"American Psychiatric Association [APA]. 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