{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T01:10:38Z","timestamp":1777511438321,"version":"3.51.4"},"reference-count":39,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2023,2,13]],"date-time":"2023-02-13T00:00:00Z","timestamp":1676246400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Brain and Behavior"],"published-print":{"date-parts":[[2023,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Heart surgery is a risk factor for objectively and subjectively assessable postoperative cognitive decline (POCD), which is relevant for everyday life. The aim of this study was to investigate whether early postoperative cognitive training has an impact on health\u2010related quality of life and cognitive failures in daily living after cardiac surgery.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The study was a two\u2010arm, randomized, controlled, outcome\u2010blinded trial involving older patients undergoing elective heart valve surgery with extracorporeal circulation (ECC). Recruitment took place at the Departments of Cardiac Surgery of the Kerckhoff Clinic in Bad Nauheim (Germany) and the University Hospital in Giessen (Germany). The patients were randomized (1:1 ratio) to either a paper\u2010and\u2010pencil\u2013based cognitive training group or a control group. We applied the Short Form Health Survey (SF\u201036) and the Cognitive Failures Questionnaire (CFQ) prior to surgery and 3 months after the cognitive training. Data were analyzed in a per\u2010protocol fashion.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Three months after discharge from rehabilitation, the training group (<jats:italic>n<\/jats:italic>\u00a0=\u00a031) showed improvement in health\u2010related quality of life compared to the control group (<jats:italic>n<\/jats:italic>\u00a0=\u00a029), especially in role limitations due to emotional problems (<jats:italic>U<\/jats:italic>\u00a0=\u00a0\u22122.649, <jats:italic>p<\/jats:italic>\u00a0=\u00a0.008, <jats:italic>\u03b7<\/jats:italic><jats:sup>2<\/jats:sup>\u00a0=\u00a00.121), energy and fatigue (<jats:italic>F<\/jats:italic>[2.55]\u00a0=\u00a05.72, <jats:italic>p<\/jats:italic>\u00a0=\u00a0.020, <jats:italic>\u03b7<\/jats:italic><jats:sup>2<\/jats:sup>\u00a0=\u00a00.062), social functioning (<jats:italic>U<\/jats:italic>\u00a0=\u00a0\u22122.137, <jats:italic>p<\/jats:italic>\u00a0=\u00a0.033, <jats:italic>\u03b7<\/jats:italic><jats:sup>2<\/jats:sup>\u00a0=\u00a00.076), the average of all SF\u201036 factors (<jats:italic>U<\/jats:italic>\u00a0=\u00a0\u22122.374, <jats:italic>p<\/jats:italic>\u00a0=\u00a0.018, <jats:italic>\u03b7<\/jats:italic><jats:sup>2<\/jats:sup>\u00a0=\u00a00.094), health change from the past year to the present time (<jats:italic>U<\/jats:italic>\u00a0=\u00a0\u22122.378, <jats:italic>p<\/jats:italic>\u00a0=\u00a0.017, <jats:italic>\u03b7<\/jats:italic><jats:sup>2<\/jats:sup>\u00a0=\u00a00.094), and the mental component summary (<jats:italic>U<\/jats:italic>\u00a0=\u00a0\u22122.470, <jats:italic>p<\/jats:italic>\u00a0=\u00a0.013, <jats:italic>\u03b7<\/jats:italic><jats:sup>2<\/jats:sup>\u00a0=\u00a00.102).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>As our cognitive training has shown beneficial effects, this intervention could be a promising method to enhance health\u2010related quality of life after cardiac surgery.<\/jats:p><\/jats:sec>","DOI":"10.1002\/brb3.2915","type":"journal-article","created":{"date-parts":[[2023,2,14]],"date-time":"2023-02-14T07:48:25Z","timestamp":1676360905000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["The impact of postoperative cognitive training on health\u2010related quality of life and cognitive failures in daily living after heart valve surgery: A randomized clinical trial"],"prefix":"10.1002","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9088-5695","authenticated-orcid":false,"given":"Marius","family":"Butz","sequence":"first","affiliation":[{"name":"Heart and Brain Research Group Kerckhoff Heart and Thorax Center  Bad Nauheim Germany"},{"name":"Department of Neurology University Hospital Giessen and Marburg  Giessen 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