{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T15:02:19Z","timestamp":1772118139396,"version":"3.50.1"},"reference-count":35,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2023,8,7]],"date-time":"2023-08-07T00:00:00Z","timestamp":1691366400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100004895","name":"European Social Fund","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004895","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000265","name":"Medical Research Council","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000265","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Brain and Behavior"],"published-print":{"date-parts":[[2023,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Sleep disturbance is an increasingly recognized non\u2010motor trait in dystonia, with varying findings reported to date. Here, we examine sleep in a UK Biobank derived dystonia cohort using subjective self\u2010reported sleep symptoms and objective accelerometer\u2010derived sleep measures, with comparison to a control population.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A total of 241 dystonia cases were compared to 964 matched controls in analysis of self\u2010reported sleep symptoms and changes in sleep architecture using wrist\u2010worn triaxial accelerometers.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Dystonia participants had poorer self\u2010reported sleep patterns compared to controls. Accelerometery measurements demonstrated later sleep times, reduced time in bed, and shifts in circadian rhythm. No association was observed with pain, and only limited relationships with psychiatric symptoms.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion<\/jats:title>\n                    <jats:p>This study demonstrates the utility of accelerometers in longer term evaluation of sleep in dystonia, for measurement of disturbance and response to treatment. Compared to controls, altered sleep and circadian rhythm were more common in dystonia patients which may contribute to the clinical phenotype.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/brb3.2933","type":"journal-article","created":{"date-parts":[[2023,8,7]],"date-time":"2023-08-07T04:38:18Z","timestamp":1691383098000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Accelerometer\u2010derived sleep measures in idiopathic dystonia: A UK Biobank cohort study"],"prefix":"10.1002","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4646-3134","authenticated-orcid":false,"given":"Grace A","family":"Bailey","sequence":"first","affiliation":[{"name":"Neuroscience and Mental Health Research Institute Division of Psychological Medicine and Clinical Neurosciences Cardiff University School of Medicine  Cardiff UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Megan E.","family":"Wadon","sequence":"additional","affiliation":[{"name":"Neuroscience and Mental Health Research Institute Division of Psychological Medicine and Clinical Neurosciences Cardiff University School of Medicine  Cardiff UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sandra","family":"Komarzynski","sequence":"additional","affiliation":[{"name":"Aparito Limited  Wrexham UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Clare","family":"Matthews","sequence":"additional","affiliation":[{"name":"Aparito Limited  Wrexham UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elin Haf","family":"Davies","sequence":"additional","affiliation":[{"name":"Aparito Limited  Wrexham UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kathryn J.","family":"Peall","sequence":"additional","affiliation":[{"name":"Neuroscience and Mental Health Research Institute Division of Psychological Medicine and Clinical Neurosciences Cardiff University School of Medicine  Cardiff UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,8,7]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/sleep\/zsx088"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468\u20101331.2009.02884.x"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp\u20102020\u2010325546"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/ene.15114"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.parkreldis.2013.12.014"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/ejp.1747"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10072\u2010021\u201005452\u20103"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s41105\u2010018\u20100185\u20103"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0169649"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.parkreldis.2014.01.004"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehz849"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcmm.14170"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.1990.00530020124024"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1093\/aje\/kwx246"},{"key":"e_1_2_10_16_1","doi-asserted-by":"crossref","unstructured":"Gorbunov A. Gromov Y. Dolgov E. Tugolukov E. &Neprokin A.(2020).Accelerometric studies of night\u2010time motor activity with essential tremor. InProc. \u2013 2020 2nd Int. Conf. Control Syst. Math. Model. Autom. Energy Effic. SUMMA(Vol.2020) (pp.642\u2013645).https:\/\/doi.org\/10.1109\/SUMMA50634.2020.9280755","DOI":"10.1109\/SUMMA50634.2020.9280755"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/ane.13304"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.smrv.2015.04.004"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1097\/PSY.0b013e3182359e77"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10865\u2010015\u20109617\u20106"},{"key":"e_1_2_10_21_1","doi-asserted-by":"crossref","unstructured":"Kyle S. D. Sexton C. E. Feige B. Luik A. I. Lane J. Saxena R. Anderson S. G. Bechtold D. A. Dixon W. Little M. A. Ray D. Riemann D. Espie C. A. Rutter M. K. &Spiegelhalder K.(2017)Sleep and cognitive performance: cross\u2010sectional associations in the UK Biobank. 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