{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T20:52:40Z","timestamp":1783457560909,"version":"3.55.0"},"reference-count":38,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2023,3,6]],"date-time":"2023-03-06T00:00:00Z","timestamp":1678060800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Brain and Behavior"],"published-print":{"date-parts":[[2023,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Dopamine D1 receptor seems to play a role in mediating plasticity. Therefore, the present study aimed to investigate the effects of passive avoidance tasks postexposed to BPA on dopamine D1 receptor density in the hippocampus, amygdala, and cerebellum of male rats.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Thirty\u2010five male Sprague\u2013Dawley rats weighing 220.300\u00a0g, in standard light\u2010dark 12 h light\/12 h dark were used in the present study; water and food were ad libitum. Animals were divided into six groups. Administration of BPA 5 and 50 mg\/kg\/day were gavaged for 15 days. Learning and memory assessment were done by a shuttle box after 15 days of BPA administration. The density of the dopamine D1 receptor was investigated using an immunohistochemistry (IH) procedure. For determining the color difference in IH sections, Image Analyzer software was used. The data were analyzed by one\u2010way ANOVA followed by Tukey's as a post hoc test.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The data showed that BPA in both doses could significantly increase the density of dopamine D1 receptors in the hippocampus, amygdala, and cerebellum of male rats; learning in rats postexposed to BPA improves dopamine D1 receptor density significantly in three brain structures.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion<\/jats:title>\n                    <jats:p>According to the results, passive avoidance learning and memory can improve the density of dopamine D1 receptors in the hippocampus, amygdala, and cerebellum of male rats.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/brb3.2942","type":"journal-article","created":{"date-parts":[[2023,3,6]],"date-time":"2023-03-06T23:54:55Z","timestamp":1678146895000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["The passive avoidance task ameliorate the toxic effects of bisphenol A on dopamine D1 receptor density in hippocampus, amygdala, and cerebellum of male rats"],"prefix":"10.1002","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8819-1619","authenticated-orcid":false,"given":"Mahnaz","family":"Taherianfard*","sequence":"first","affiliation":[{"name":"Physiology Division of Basic Science Department, School of Veterinary Medicine Shiraz University  Shiraz Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saiedeh","family":"Ahmadijokani","sequence":"additional","affiliation":[{"name":"Physiology Division of Basic Science Department, School of Veterinary Medicine Shiraz University  Shiraz Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,3,6]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1177\/1559325815610582"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ynstr.2020.100219"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1093\/schbul\/sbm147"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1080\/713853983"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuropharm.2017.04.033"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1816704116"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1289\/ehp.110\u20101241190"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnins.2018.00084"},{"key":"e_1_2_10_10_1","first-page":"3","article-title":"Stimulation of D1\u2010receptors improves passive avoidance learning of female rats during ovary cycle","volume":"75","author":"Fedotova Iu O.","year":"2012","journal-title":"Eksperimental'naya I Klinicheskaya Farmakologiya"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M200849200"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/andr.12176"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.2486\/indhealth.44.510"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.7150\/ijms.13267"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/jnr.20050"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440\u20101789.2011.01287.x"},{"key":"e_1_2_10_17_1","first-page":"1","article-title":"The molecular mechanism of bisphenol A (BPA) as an endocrine disruptor by interacting with nuclear receptors: insights from molecular dynamics (MD) simulations","volume":"1","author":"Li L.","year":"2015","journal-title":"PLoS One"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1098\/rspb.2015.2272"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neulet.2007.01.088"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365\u20102826.2006.01434.x"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1101\/lm.461407"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1369\u20101600.2007.00048.x"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.brainres.2005.11.100"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroscience.2010.02.051"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.1289\/ehp.00108s3511"},{"key":"e_1_2_10_26_1","first-page":"106","volume-title":"IEEE Engineering in Medicine and Biology Magazine","author":"Rittscher J.","year":"2008"},{"key":"e_1_2_10_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroscience.2014.08.038"},{"key":"e_1_2_10_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0306\u20104522(02)00935\u20101"},{"key":"e_1_2_10_29_1","first-page":"190","article-title":"Effect of bisphenol A on passive avoidance performance in male rats","volume":"4","author":"Taherianfard M.","year":"2013","journal-title":"American Medical Journal"},{"key":"e_1_2_10_30_1","first-page":"140","article-title":"Modulation of NR1 subunit of N\u2010methyl\u2010D\u2010aspartate receptor by ovariectomy and passive avoidance learning","volume":"11","author":"Taherianfard M.","year":"2012","journal-title":"Iranian Journal of Neurology"},{"key":"e_1_2_10_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.braindev.2006.10.003"},{"key":"e_1_2_10_32_1","doi-asserted-by":"publisher","DOI":"10.1002\/syn.20746"},{"key":"e_1_2_10_33_1","doi-asserted-by":"publisher","DOI":"10.1002\/dneu.20839"},{"key":"e_1_2_10_34_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms20246206"},{"key":"e_1_2_10_35_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598\u2010018\u201022668\u20100"},{"key":"e_1_2_10_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuro.2007.01.012"},{"key":"e_1_2_10_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ntt.2020.106884"},{"key":"e_1_2_10_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.yhbeh.2010.02.012"},{"key":"e_1_2_10_39_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuropharm.2011.01.031"}],"container-title":["Brain and Behavior"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/brb3.2942","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/brb3.2942","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/brb3.2942","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,20]],"date-time":"2023-08-20T12:49:10Z","timestamp":1692535750000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/brb3.2942"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,3,6]]},"references-count":38,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2023,4]]}},"alternative-id":["10.1002\/brb3.2942"],"URL":"https:\/\/doi.org\/10.1002\/brb3.2942","archive":["Portico"],"relation":{"has-review":[{"id-type":"doi","id":"10.1002\/BRB3.2942\/v1\/review1","asserted-by":"object"},{"id-type":"doi","id":"10.1002\/BRB3.2942\/v3\/response1","asserted-by":"object"},{"id-type":"doi","id":"10.1002\/BRB3.2942\/v1\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1002\/BRB3.2942\/v2\/response1","asserted-by":"object"},{"id-type":"doi","id":"10.1002\/BRB3.2942\/v2\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1002\/BRB3.2942\/v3\/decision1","asserted-by":"object"}]},"ISSN":["2162-3279","2162-3279"],"issn-type":[{"value":"2162-3279","type":"print"},{"value":"2162-3279","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,3,6]]},"assertion":[{"value":"2021-09-27","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-03-23","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-03-06","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e2942"}}