{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,26]],"date-time":"2026-10-26T18:41:03Z","timestamp":1793040063396,"version":"4.5.0"},"reference-count":39,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2023,3,14]],"date-time":"2023-03-14T00:00:00Z","timestamp":1678752000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Brain and Behavior"],"published-print":{"date-parts":[[2023,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>While functional near\u2010infrared spectroscopy (fNIRS) can provide insight into motor\u2010cognitive deficits during ecologically valid gait conditions, the feasibility of using fNIRS during complex walking remains unknown. We tested the process and scientific feasibility of using an fNIRS device to measure cortical activity during complex walking tasks consisting of straight walking and navigated walking under single and dual\u2010task (DT) conditions.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Nineteen healthy people from 18 to 64 years (mean age: 45.7 years) participated in this study which consisted of three complex walking protocols: (i) straight walking, DT walking (walking while performing an auditory Stroop task) and single\u2010task auditory Stroop, (ii) straight and navigated walking, and (iii) navigated walking and navigated DT walking. A rest condition (standing still) was also included in each protocol. Process feasibility outcomes included evaluation of the test procedures and participant experience during and after each protocol. Scientific feasibility outcomes included signal quality measures, and the ability to measure changes in concentration of deoxygenated and oxygenated hemoglobin in the prefrontal cortex.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>All participants were able to complete the three protocols with most agreeing that the equipment was comfortable (57.9%) and that the testing duration was adequate (73.7%). Most participants did not feel tired (94.7%) with some experiencing pain (42.1%) during the protocols. The signal qualities were high for each protocol. Compared to the rest condition, there was an increase in oxygenated hemoglobin in the prefrontal cortex when performing dual\u2010task walking and navigation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>We showed that our experimental setup was feasible for assessing activity in the prefrontal cortex with fNIRS during complex walking. The experimental setup was deemed acceptable and practicable. Signal quality was good during complex walking conditions and findings suggest that the different tasks elicit a differential brain activity, supporting scientific feasibility.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/brb3.2948","type":"journal-article","created":{"date-parts":[[2023,3,14]],"date-time":"2023-03-14T13:14:00Z","timestamp":1678799640000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["Using functional near\u2010infrared spectroscopy to measure prefrontal cortex activity during dual\u2010task walking and navigated walking: A feasibility study"],"prefix":"10.1002","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7431-2144","authenticated-orcid":false,"given":"Alexander","family":"Kvist","sequence":"first","affiliation":[{"name":"Department of Neurobiology, Care sciences and Society, Division of Physiotherapy Karolinska Institutet  Stockholm Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucian","family":"Bezuidenhout","sequence":"additional","affiliation":[{"name":"Department of Neurobiology, Care sciences and Society, Division of Physiotherapy Karolinska Institutet  Stockholm Sweden"},{"name":"Faculty of Community and Health Sciences University of Western Cape  Cape Town South Africa"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hanna","family":"Johansson","sequence":"additional","affiliation":[{"name":"Department of Neurobiology, Care sciences and Society, Division of Physiotherapy Karolinska Institutet  Stockholm Sweden"},{"name":"Women's Health and Allied Health Professionals Theme, Medical Unit Occupational Therapy &amp; Physiotherapy Karolinska University Hospital  Stockholm Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Franziska","family":"Albrecht","sequence":"additional","affiliation":[{"name":"Department of Neurobiology, Care sciences and Society, Division of Physiotherapy Karolinska Institutet  Stockholm Sweden"},{"name":"Women's Health and Allied Health Professionals Theme, Medical Unit Occupational Therapy &amp; Physiotherapy Karolinska University Hospital  Stockholm Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Urban","family":"Ekman","sequence":"additional","affiliation":[{"name":"Department of Neurobiology, Care Sciences and Society, Division of Clinical Geriatrics Karolinska Institutet  Stockholm Sweden"},{"name":"Women's Health and Allied Health Professionals Theme, Medical Unit Medical Psychology Karolinska University Hospital  Stockholm Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David Moulaee","family":"Conradsson","sequence":"additional","affiliation":[{"name":"Department of Neurobiology, Care sciences and Society, Division of Physiotherapy Karolinska Institutet  Stockholm Sweden"},{"name":"Women's Health and Allied Health Professionals Theme, Medical Unit Occupational Therapy &amp; Physiotherapy Karolinska University Hospital  Stockholm Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erika","family":"Franz\u00e9n","sequence":"additional","affiliation":[{"name":"Department of Neurobiology, Care sciences and Society, Division of Physiotherapy Karolinska Institutet  Stockholm Sweden"},{"name":"Women's Health and Allied Health Professionals Theme, Medical Unit Occupational Therapy &amp; Physiotherapy Karolinska University Hospital  Stockholm Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,3,14]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bandc.2005.11.009"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.25674"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1364\/BOE.4.001366"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.3390\/brainsci11030291"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/brb3.724"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnhum.2015.00246"},{"key":"e_1_2_11_8_1","article-title":"Delis\u2014Kaplan Executive Function System: Examiner's Manual","author":"Delis D. 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