{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T14:59:34Z","timestamp":1772117974330,"version":"3.50.1"},"reference-count":14,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2023,5,24]],"date-time":"2023-05-24T00:00:00Z","timestamp":1684886400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Brain and Behavior"],"published-print":{"date-parts":[[2023,7]]},"abstract":"Abstract<\/jats:title>\n \n Objective<\/jats:title>\n Individuals with mental illnesses are exposed to an increased risk of suicide. In this study, we aimed to investigate the clinical characteristics and outcome of psychiatric patients who attempted suicide by drug overdose and required emergency care.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n A retrospective study was carried out in the Department of Emergency, the First Affiliated Hospital, Zhejiang University School of Medicine. Electronic medical records of psychiatric patients who were hospitalized due to suicide attempts from March 2019 to February 2022, with a discharge diagnosis of drug overdose were reviewed. Suicide\u2010related data of patients were collected, including suicide month, time from suicide to admission, type of drugs, the number of tablets taken, as well as demographic and clinical profiles (e.g., gender, age, marital status, profession, physical comorbidities, and diagnosis of mental illness).<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n In the results, half of the patients were young people, female patients accounted for a higher proportion (72.5%), and the incidence of suicide was higher in winter than other seasons. Among the 109 psychiatric patients, 60 patients (55.0%) had a history of major depressive disorder, and 86 patients (78.9%) committed suicide with various psychotropic drugs, among which anxiolytics were the most commonly used drugs. Thirty\u2010seven patients (33.9%) experienced severe physical complications caused by drug overdose, with lung infections being the most common. The clinical outcome of most patients was favorable following emergent treatment, while 2 patients (1.8%) older than 80 failed to survive.<\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n A better understanding of psychiatric patients referred to emergency care due to suicide by drug overdose helps to improve the clinical management and prognosis of patients.<\/jats:p>\n <\/jats:sec>","DOI":"10.1002\/brb3.3058","type":"journal-article","created":{"date-parts":[[2023,5,25]],"date-time":"2023-05-25T02:38:58Z","timestamp":1684982338000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Clinical characteristics and outcomes of patients with mental illnesses who attempted suicide by drug overdose: A retrospective analysis of 109 cases"],"prefix":"10.1002","volume":"13","author":[{"given":"Naiyun","family":"Chen","sequence":"first","affiliation":[{"name":"Department of Emergency Medicine the First Affiliated Hospital, Zhejiang University School of Medicine Hangzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shaoli","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Medical Oncology, the Second Affiliated Hospital Zhejiang University School of Medicine Hangzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shu","family":"Huang","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, the First Affiliated Hospital Zhejiang University School of Medicine Hangzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4674-4000","authenticated-orcid":false,"given":"Jianbo","family":"Lai","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, the First Affiliated Hospital Zhejiang University School of Medicine Hangzhou China"},{"name":"The Key Laboratory of Mental Disorder's Management in Zhejiang Province Hangzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Duo","family":"Lv","sequence":"additional","affiliation":[{"name":"Department of Clinical Pharmacy, the First Affiliated Hospital Zhejiang University School of Medicine Hangzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,5,24]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00127-011-0393-5"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/wps.20128"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1017\/S2045796017000129"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jad.2017.12.008"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40211-016-0181-2"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11920-020-1130-0"},{"key":"e_1_2_8_8_1","volume-title":"Screening for suicide risk in primary care: A systematic evidence review for the U.S. Preventive Services Task Force [Internet]","author":"O'Connor E.","year":"2013"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpsychires.2011.06.002"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/hsr2.662"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jad.2019.08.054"},{"key":"e_1_2_8_12_1","unstructured":"WHO Mental Health.Prevention of suicidal behaviours: A task for all. Available online:http:\/\/www.who.int\/mental_health\/prevention\/suicide\/background(accessed on 27 May 2022)"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0219048"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajp.2018.10.015"},{"key":"e_1_2_8_15_1","first-page":"13","article-title":"Suicide attempts and emergency room psychiatric consultation","volume":"15","author":"Zeppegno P.","year":"2015","journal-title":"Bmc Psychiatry [Electronic Resource]"}],"container-title":["Brain and Behavior"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/brb3.3058","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,18]],"date-time":"2023-08-18T01:13:19Z","timestamp":1692321199000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/brb3.3058"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,5,24]]},"references-count":14,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2023,7]]}},"alternative-id":["10.1002\/brb3.3058"],"URL":"https:\/\/doi.org\/10.1002\/brb3.3058","archive":["Portico"],"relation":{"has-review":[{"id-type":"doi","id":"10.1002\/BRB3.3058\/v2\/review1","asserted-by":"object"},{"id-type":"doi","id":"10.1002\/BRB3.3058\/v1\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1002\/BRB3.3058\/v2\/response1","asserted-by":"object"},{"id-type":"doi","id":"10.1002\/BRB3.3058\/v1\/review1","asserted-by":"object"},{"id-type":"doi","id":"10.1002\/BRB3.3058\/v3\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1002\/BRB3.3058\/v3\/response1","asserted-by":"object"},{"id-type":"doi","id":"10.1002\/BRB3.3058\/v2\/decision1","asserted-by":"object"}]},"ISSN":["2162-3279","2162-3279"],"issn-type":[{"value":"2162-3279","type":"print"},{"value":"2162-3279","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,5,24]]},"assertion":[{"value":"2023-01-18","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-04-27","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-05-24","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e3058"}}