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Using a multiparameter morphometric imaging approach, we aimed to characterize neuroanatomical differences between young adult women (18\u201330 years old) who were exposed to frequent sexual choking and their choking na\u00efve controls.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This cross\u2010sectional study consisted of two groups (choking [\u22654 times in the past 30 days] vs. choking\u2010na\u00efve group). Participants who reported being choked four or more times during sex in the past 30 days were enrolled in the choking group, whereas those without were assigned to the choking na\u00efve group. High\u2010resolution anatomical magnetic resonance imaging (MRI) data were analyzed using both volumetric features (cortical thickness) and geometric features (fractal dimensionality, gyrification, sulcal depth).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Forty\u2010one participants (choking\n                      <jats:italic>n<\/jats:italic>\n                      \u00a0=\u00a020; choking\u2010na\u00efve\n                      <jats:italic>n<\/jats:italic>\n                      \u00a0=\u00a021) contributed to the final analysis. The choking group showed significantly increased cortical thickness across multiple regions (e.g., fusiform, lateral occipital, lingual gyri) compared to the choking\u2010na\u00efve group. Widespread reductions of the gyrification were observed in the choking group as opposed to the choking\u2010na\u00efve group. However, there was no group difference in sulcal depth. The fractal dimensionality showed bi\u2010directional results, where the choking group exhibited increased dimensionality in areas including the postcentral gyrus, insula, and fusiform, whereas decreased dimensionality was observed in the bilateral superior frontal gyrus and pericalcarine cortex.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>These data in cortical morphology suggest that sexual choking events may be associated with neuroanatomical alteration. A longitudinal study with multimodal assessment is needed to better understand the temporal ordering of sexual choking and neurological outcomes.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/brb3.3160","type":"journal-article","created":{"date-parts":[[2023,7,17]],"date-time":"2023-07-17T12:49:40Z","timestamp":1689598180000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":19,"title":["Structural brain morphology in young adult women who have been choked\/strangled during sex: A whole\u2010brain surface morphometry study"],"prefix":"10.1002","volume":"13","author":[{"given":"Jiancheng","family":"Hou","sequence":"first","affiliation":[{"name":"Research Center for Cross\u2010Straits Cultural Development Fujian Normal University Fuzhou China"},{"name":"Department of Kinesiology Indiana University School of Public Health\u2010Bloomington Bloomington Indiana USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Megan E.","family":"Huibregtse","sequence":"additional","affiliation":[{"name":"Department of Kinesiology Indiana University School of Public Health\u2010Bloomington Bloomington Indiana USA"},{"name":"Department of Psychiatry and Behavioral Sciences Emory University School of Medicine Atlanta Georgia USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isabella L.","family":"Alexander","sequence":"additional","affiliation":[{"name":"Department of Kinesiology Indiana University School of Public Health\u2010Bloomington Bloomington Indiana USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lillian M.","family":"Klemsz","sequence":"additional","affiliation":[{"name":"Department of Kinesiology Indiana University School of Public Health\u2010Bloomington Bloomington Indiana USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tsung\u2010Chieh","family":"Fu","sequence":"additional","affiliation":[{"name":"Department of Applied Health Science, Indiana University School of Public Health Indiana University Bloomington Indiana USA"},{"name":"The Center for Sexual Health Promotion, Indiana University School of Public Health Indiana University Bloomington Indiana USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Molly","family":"Rosenberg","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Biostatistics, Indiana University School of Public Health Indiana University Bloomington Indiana USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James Dennis","family":"Fortenberry","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Indiana University School of Medicine Indiana University Indianapolis Indiana USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Debby","family":"Herbenick","sequence":"additional","affiliation":[{"name":"Department of Applied Health Science, Indiana University School of Public Health Indiana University Bloomington Indiana USA"},{"name":"The Center for Sexual Health Promotion, Indiana University School of Public Health Indiana University Bloomington Indiana USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4135-9311","authenticated-orcid":false,"given":"Keisuke","family":"Kawata","sequence":"additional","affiliation":[{"name":"Department of Kinesiology Indiana University School of Public Health\u2010Bloomington Bloomington Indiana USA"},{"name":"Program in Neuroscience The College of Arts and Sciences Indiana University Bloomington Indiana USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,7,17]]},"reference":[{"key":"e_1_2_10_2_1","article-title":"Chronic elevation of serum S100B but not neurofilament\u2010light due to frequent choking\/strangulation during sex in young adult women","author":"Alexander I. 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