{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T03:47:18Z","timestamp":1790912838633,"version":"4.1.0"},"reference-count":49,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2023,8,3]],"date-time":"2023-08-03T00:00:00Z","timestamp":1691020800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Brain and Behavior"],"published-print":{"date-parts":[[2023,10]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>\n                      Recent literature suggests that goal\u2010oriented and family\u2010based interventions in enriched environment have a beneficial effect on neuromotor and cognitive development. We aimed to examine the short\u2010term effects of SAFE (\n                      <jats:bold>S<\/jats:bold>\n                      ensory strategies,\n                      <jats:bold>A<\/jats:bold>\n                      ctivity\u2010based motor training,\n                      <jats:bold>F<\/jats:bold>\n                      amily collaboration, and\n                      <jats:bold>E<\/jats:bold>\n                      nvironmental Enrichment) early intervention approach on motor, cognitive, speech and language, and sensory development in preterm infants.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>The study's sample population consisted of 24 preterm infants with corrected ages between 9 and 10 months. Infants in the control group participated in the family training program in accordance with the neurodevelopmental therapy\u00a0principles (NDT). Infants in the treatment group were included in the family training program according to the principles of the SAFE Early Intervention Approach. Affordances in the Home Environment for Motor Development\u2010Infant Scale (AHEMD\u2010IS), Test of Sensory Functions in Infants (TSFI), Canadian Occupational Performance Measure (COPM), and Bayley Scales of Infant and Toddler Development III (Bayley III) were used to evaluate infants in both groups before and after 10 weeks of treatment (AHEMD\u2010IS). The Depression, Anxiety, Stress Scale Short Form was used to assess the parents\u2019 mental health (DASS\u2010SF).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The interaction effects (time \u00d7 group) revealed significant differences for Bayley\u2010III cognitive and language scores, TSFI total score, and AHEMD\u2010IS total score in favor of the SAFE group (\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0&lt;\u00a0.05). However, there were no differences in Bayley\u2010III motor composite score, COPM Performance score, and COPM Satisfaction score between the interaction effects (time \u00d7 group) of the groups (\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0&gt;\u00a0.05).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>SAFE early intervention approach improved cognitive, speech and language, sensory outcomes and provide enriched home environment in all domains when compared to NDT\u2010based home program. SAFE is a promising novel early intervention approach for preterm infants.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/brb3.3199","type":"journal-article","created":{"date-parts":[[2023,8,3]],"date-time":"2023-08-03T06:39:08Z","timestamp":1691044748000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":23,"title":["Short\u2010term effects of SAFE early intervention approach in infants born preterm: A randomized controlled single\u2010blinded study"],"prefix":"10.1002","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0866-5870","authenticated-orcid":false,"given":"Umut","family":"Apayd\u0131n","sequence":"first","affiliation":[{"name":"Faculty of Health Sciences, Department of Physiotherapy and Rehabilitation Karadeniz Technical University Trabzon Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ramazan","family":"Y\u0131ld\u0131z","sequence":"additional","affiliation":[{"name":"Faculty of Health Sciences, Department of Physiotherapy and Rehabilitation Gazi University Ankara Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ay\u015fe","family":"Y\u0131ld\u0131z","sequence":"additional","affiliation":[{"name":"Faculty of Health Sciences, Department of Physiotherapy and Rehabilitation Gazi University Ankara Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u015eebnem Soysal","family":"Acar","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Department of Pediatrics, Section of Pediatric Neurology Gazi University Ankara Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K\u0131v\u0131lc\u0131m","family":"G\u00fcc\u00fcyener","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Department of Pediatrics, Section of Pediatric Neurology Gazi University Ankara Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B\u00fclent","family":"Elbasan","sequence":"additional","affiliation":[{"name":"Faculty of Health Sciences, Department of Physiotherapy and Rehabilitation Gazi University Ankara Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,8,3]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/dmcn.14493"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1590\/1518\u20108345.0710.2753"},{"key":"e_1_2_11_4_1","volume-title":"Bayley\u2010III: Bayley Scales of Infant and Toddler Development","author":"Bayley N.","year":"2006"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.288.6.728"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/00001163\u2010200210000\u201000004"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neubiorev.2007.04.010"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.2522\/ptj.20100205"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0012162205000824"},{"key":"e_1_2_11_10_1","first-page":"793","article-title":"The bioecological model of human development","volume":"1","author":"Bronfenbrenner U.","year":"2007","journal-title":"Handbook of Child Psychology"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1442\u2010200X.2011.03386.x"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1590\/bjpt\u2010rbf.2014.0112"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.5014\/ajot.2018.026260"},{"key":"e_1_2_11_14_1","volume-title":"Statistical power analysis for the behavioral sciences","author":"Cohen J.","year":"1988"},{"key":"e_1_2_11_15_1","first-page":"189","volume-title":"Effects of motor activity on brain and muscle development in cerebral palsy","author":"Damiano D.","year":"2013"},{"key":"e_1_2_11_16_1","volume-title":"Test of Sensory Functions in Infants (TSFI)","author":"DeGangi G. A.","year":"1989"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.earlhumdev.2019.104852"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.2522\/ptj.20100207"},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469\u20108749.2011.04067.x"},{"key":"e_1_2_11_20_1","first-page":"5","article-title":"Sensory strategies: Practical support to empower families","volume":"55","author":"Dunstan E.","year":"2008","journal-title":"New Zealand Journal of Occupational Therapy"},{"key":"e_1_2_11_21_1","doi-asserted-by":"publisher","DOI":"10.1093\/ptj\/pzaa077"},{"key":"e_1_2_11_22_1","doi-asserted-by":"publisher","DOI":"10.1097\/PEP.0000000000000161"},{"key":"e_1_2_11_23_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12887\u2010018\u20101011\u20104"},{"key":"e_1_2_11_24_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2013\u20101021H"},{"key":"e_1_2_11_25_1","doi-asserted-by":"publisher","DOI":"10.1177\/030802261407701204"},{"key":"e_1_2_11_26_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0012162200001316"},{"key":"e_1_2_11_27_1","doi-asserted-by":"publisher","DOI":"10.1080\/09638288.2019.1610508"},{"key":"e_1_2_11_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pediatrneurol.2010.11.009"},{"issue":"1","key":"e_1_2_11_29_1","first-page":"1","article-title":"Intensive training of motor function and functional skills among young children with cerebral palsy: A systematic review and meta\u2010analysis","volume":"14","author":"Jahnsen R.","year":"2014","journal-title":"BMC Pediatrics [Electronic Resource]"},{"key":"e_1_2_11_30_1","doi-asserted-by":"publisher","DOI":"10.5014\/ajot.51.9.733"},{"key":"e_1_2_11_31_1","doi-asserted-by":"publisher","DOI":"10.1080\/03004430.2020.1727463"},{"key":"e_1_2_11_32_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469\u20108749.2011.03962.x"},{"key":"e_1_2_11_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/0005\u20107967(94)00075\u2010U"},{"key":"e_1_2_11_34_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.DBP.0000257517.52459.7a"},{"key":"e_1_2_11_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.infbeh.2012.02.002"},{"key":"e_1_2_11_36_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2012\u20103985"},{"key":"e_1_2_11_37_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12887\u2010015\u20100347\u20102"},{"key":"e_1_2_11_38_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12883\u2010014\u20100203\u20102"},{"key":"e_1_2_11_39_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ridd.2016.04.005"},{"key":"e_1_2_11_40_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1601\u20105215.2007.00217.x"},{"key":"e_1_2_11_41_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11910\u2010020\u20101022\u2010z"},{"key":"e_1_2_11_42_1","doi-asserted-by":"publisher","DOI":"10.1177\/0031512516662895"},{"key":"e_1_2_11_43_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2013\u20100675"},{"key":"e_1_2_11_44_1","first-page":"19","article-title":"The psychometric properties of Turkish version of Depression Anxiety Stress Scale\u201021 (DASS\u201021) in health control and clinical samples","volume":"7","author":"Saricam H.","year":"2018","journal-title":"Journal of Cognitive\u2010Behavioral Psychotherapy and Research"},{"key":"e_1_2_11_45_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0197\u20102456(02)00242\u20108"},{"key":"e_1_2_11_46_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471\u20102431\u201014\u2010268"},{"key":"e_1_2_11_47_1","first-page":"12","article-title":"Early developmental intervention programmes post\u2010hospital discharge to prevent motor and cognitive impairments in preterm infants","volume":"1","author":"Spittle A.","year":"2012","journal-title":"Cochrane Database of Systematic Reviews (Online)"},{"key":"e_1_2_11_48_1","first-page":"11","article-title":"Early developmental intervention programmes provided post hospital discharge to prevent motor and cognitive impairment in preterm infants","volume":"1","author":"Spittle A.","year":"2015","journal-title":"Cochrane Database of Systematic Reviews (Online)"},{"key":"e_1_2_11_49_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2021\u2010055061"},{"key":"e_1_2_11_50_1","doi-asserted-by":"publisher","DOI":"10.1037\/0003\u2010066X.50.2.79"}],"container-title":["Brain and Behavior"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/brb3.3199","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,13]],"date-time":"2023-10-13T00:35:39Z","timestamp":1697157339000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/brb3.3199"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,8,3]]},"references-count":49,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2023,10]]}},"alternative-id":["10.1002\/brb3.3199"],"URL":"https:\/\/doi.org\/10.1002\/brb3.3199","archive":["Portico"],"relation":{"has-review":[{"id-type":"doi","id":"10.1002\/BRB3.3199\/v1\/review3","asserted-by":"object"},{"id-type":"doi","id":"10.1002\/BRB3.3199\/v2\/review1","asserted-by":"object"},{"id-type":"doi","id":"10.1002\/BRB3.3199\/v2\/response1","asserted-by":"object"},{"id-type":"doi","id":"10.1002\/BRB3.3199\/v2\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1002\/BRB3.3199\/v3\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1002\/BRB3.3199\/v1\/review1","asserted-by":"object"},{"id-type":"doi","id":"10.1002\/BRB3.3199\/v2\/review2","asserted-by":"object"},{"id-type":"doi","id":"10.1002\/BRB3.3199\/v1\/review2","asserted-by":"object"},{"id-type":"doi","id":"10.1002\/BRB3.3199\/v1\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1002\/BRB3.3199\/v3\/response1","asserted-by":"object"}]},"ISSN":["2162-3279","2162-3279"],"issn-type":[{"value":"2162-3279","type":"print"},{"value":"2162-3279","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,8,3]]},"assertion":[{"value":"2023-03-28","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-07-22","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-08-03","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e3199"}}