{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T16:13:08Z","timestamp":1777392788502,"version":"3.51.4"},"reference-count":43,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2023,9,24]],"date-time":"2023-09-24T00:00:00Z","timestamp":1695513600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["JP19K17031"],"award-info":[{"award-number":["JP19K17031"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Brain and Behavior"],"published-print":{"date-parts":[[2023,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Purpose<\/jats:title><jats:p>We have reported the relationship between low pulvinar nuclei (PN) intensity in susceptibility\u2010weighted imaging and the appearance of visual hallucinations and cognitive function. The aim of the study was to examine the changes in the quantitative susceptibility mapping (QSM) in patients with Parkinson's disease (PD) who underwent deep brain stimulation (DBS) and verify whether the PN susceptibility value (SV) on QSM can predict visual hallucination and cognitive changes after DBS.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This study examined 24 patients with PD who underwent DBS along with QSM imaging on magnetic resonance imaging (MRI). All MRIs were performed within 3 months before surgery. The PN SV was further assessed based on the QSM. Then, associations were examined among cognitive changes, hallucination, and PN SV. The cognitive function of the patient was compared immediately before surgery and at 1 year postoperatively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Visual hallucinations were observed in seven patients during the follow\u2010up period. The PN SV was \u22650.045\u00a0ppm in nine patients with PD, and six of them had visual hallucinations, whereas only one of 15 patients with PD with SV of\u00a0&lt;0.045\u00a0ppm had visual hallucinations (Fisher's exact test, <jats:italic>p<\/jats:italic> = .0037).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The SV of\u00a0&gt;0.045\u00a0ppm at the PN in QSM in patients with PD may provide useful information suggesting visual hallucination and cognitive deterioration after DBS treatment.<\/jats:p><\/jats:sec>","DOI":"10.1002\/brb3.3263","type":"journal-article","created":{"date-parts":[[2023,9,25]],"date-time":"2023-09-25T04:53:42Z","timestamp":1695617622000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Pulvinar quantitative susceptibility mapping predicts visual hallucinations post\u2010deep brain stimulation in Parkinson's disease"],"prefix":"10.1002","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4073-2340","authenticated-orcid":false,"given":"Keita","family":"Matsuura","sequence":"first","affiliation":[{"name":"Department of Neurology, Graduate School of Medicine Mie University  Mie Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuichiro","family":"Ii","sequence":"additional","affiliation":[{"name":"Department of Neuroimaging and Pathophysiology Mie University School of Medicine  Mie Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masayuki","family":"Maeda","sequence":"additional","affiliation":[{"name":"Department of Neuroradiology, Graduate School of Medicine Mie University  Mie Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ken\u2010ichi","family":"Tabei","sequence":"additional","affiliation":[{"name":"School of Industrial Technology, Advanced Institute of Industrial Technology Tokyo Metropolitan Public 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