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The COvid Mental hEalth Trial was specifically designed to evaluate the impact of the COVID\u201019 pandemic and its containment measures on the mental health of the Italian general population in terms of COVID\u201019\u2010related acute stress disorder (ASD) symptoms.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>The present cross\u2010sectional study is based on an online survey carried out in the period March\u2013May 2020. Italian general adult population was invited to compile an anonymous survey, which included the severity of acute stress symptoms scale\/National Stressful Events Survey Short Scale to investigate the occurrence and severity of ASD symptoms.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The final sample consisted of 20,720 participants. During the lockdown, subjects with pre\u2010existing mental health problems reported a statistically significant higher risk of acute post\u2010traumatic symptoms compared to the general population (\n                      <jats:italic>B<\/jats:italic>\n                      : 2.57; 95% CI:2.04\u20133.09;\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0&lt;\u00a0.0001) and health care professionals (\n                      <jats:italic>B<\/jats:italic>\n                      : .37; 95% CI: .02\u20130.72;\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0&lt;\u00a0.05). According to multivariate regression models, the levels of acute post\u2010traumatic symptoms (\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0&lt;\u00a0.0001) were higher in younger and female respondents. Social isolation and sleep disorder\/insomnia represented positive predictors of acute stress (\n                      <jats:italic>B<\/jats:italic>\n                      \u00a0=\u00a03.32, 95% CI\u00a0=\u00a03.08\u20133.57).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Concerns about the risk of infection as well as social isolation caused a higher incidence of acute post\u2010traumatic stress symptoms that may predict the subsequent development of post\u2010traumatic stress disorder symptoms in the long term.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/brb3.3314","type":"journal-article","created":{"date-parts":[[2023,11,23]],"date-time":"2023-11-23T18:48:15Z","timestamp":1700765295000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Acute stress symptoms in general population during the first wave of COVID lockdown in Italy: Results from the COMET trial"],"prefix":"10.1002","volume":"13","author":[{"given":"Claudia","family":"Carmassi","sequence":"first","affiliation":[{"name":"Department of Clinical and Experimental Medicine University of Pisa  Pisa Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9547-2793","authenticated-orcid":false,"given":"Gaia","family":"Sampogna","sequence":"additional","affiliation":[{"name":"Department of Psychiatry University of Campania \u201cL. 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