{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T14:59:38Z","timestamp":1772117978714,"version":"3.50.1"},"reference-count":42,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2024,2,5]],"date-time":"2024-02-05T00:00:00Z","timestamp":1707091200000},"content-version":"vor","delay-in-days":4,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Brain and Behavior"],"published-print":{"date-parts":[[2024,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>Early detection of cognitive impairment is essential for timely intervention. Currently, most widely used cognitive screening tests are influenced by language and cultural differences; therefore, there is a need for the development of a language\u2010neutral, visual\u2010based cognitive assessment tool. The Visual Cognitive Assessment Test (VCAT), a 30\u2010point test that assesses memory, executive function, visuospatial function, attention, and language, has demonstrated its utility in a multilingual population. In this study, we evaluated the reliability, validity, and diagnostic performance of the VCAT for screening early cognitive impairment in Chongqing, China<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A total of 134 individuals (49 healthy controls (HCs), 52 with mild cognitive impairment (MCI), and 33 with mild dementia) completed the Mini\u2010Mental State Examination (MMSE), Montreal Cognitive Assessment (MoCA), VCAT, and domain\u2010specific neuropsychological assessments. The diagnostic performances of MMSE, MoCA, and VCAT were evaluated using the area under the curve (AUC), sensitivity, and specificity. Construct validity of the VCAT was assessed with well\u2010established domain\u2010specific cognitive assessments. Reliability was measured using Cronbach's alpha.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The VCAT and its subdomains demonstrated both good construct validity and internal consistency (\u03b1\u00a0=\u00a00.577). The performance of VCAT was comparable to that of MoCA and MMSE in differentiating mild dementia from nondemented groups (AUC: 0.940\u00a0vs. 0.902 and 0.977, respectively;\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a0.098 and .053) and in distinguishing cognitive impairment (CI) from HC (AUC: 0.929\u00a0vs. 0.899 and 0.891, respectively;\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a0.239 and .161), adjusted for education level. The optimal score range for VCAT in determining dementia, MCI, and HC was 0\u201314, 15\u201319, and 20\u201330, respectively.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The VCAT proves to be a reliable screening test for early cognitive impairment within our cohort. Being both language and cultural neutral, the VCAT has the potential to be utilized among a wider population within China.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/brb3.3413","type":"journal-article","created":{"date-parts":[[2024,2,7]],"date-time":"2024-02-07T03:14:07Z","timestamp":1707275647000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Visual Cognitive Assessment Test: Utility of the brief cognitive battery for early screening of cognitive impairment in Chongqing, China"],"prefix":"10.1002","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1059-0919","authenticated-orcid":false,"given":"Yidan","family":"Liu","sequence":"first","affiliation":[{"name":"Department of Neurology the Second Affiliated Hospital of Chongqing Medical University  Chongqing China"},{"name":"Department of Neurology Chengdu seventh People's Hospital  Chengdu 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