{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,27]],"date-time":"2026-03-27T13:21:14Z","timestamp":1774617674464,"version":"3.50.1"},"reference-count":30,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2024,4,30]],"date-time":"2024-04-30T00:00:00Z","timestamp":1714435200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Brain and Behavior"],"published-print":{"date-parts":[[2024,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To investigate the circadian changes of the autonomic function in patients with zoster\u2010associated pain (ZAP).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A total of 37 patients with ZAP from April 2022 to October 2022 were enrolled as the observation group, and 37 normal volunteers at the same time were selected as the control group. All participants were required to wear a 24\u2010h Holter, which was used to compare the heart rate variability (HRV) between the two groups. HRV analysis involved time\u2010 and frequency\u2010domain parameters.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      There was no statistically significant difference in general information between two groups. Patients with ZAP had an increased mean heart rate and decreased the standard deviation of normal\u2010to\u2010normal (SDNN) R\u2013R interval, the root mean square of the differences (RMSSD) in successive RR interval, low frequency (LF), and high frequency (HF) compared with control groups in all periods (\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0&lt;\u00a0.05). The ratio of LF\/HF between two groups had no significant difference (\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a0.245). SDNN had no significant difference between day and night in the control group (\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0&gt;\u00a0.05), whereas SDNN of ZAP patients in night period was reduced than that in day period (\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0&lt;\u00a0.001). The level of RMSSD during the day was lower than those at night in the control group (\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0&lt;\u00a0.05), whereas no significant difference of RMSSD between two periods was observed in patients with ZAP (\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0&gt;\u00a0.05).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The results of this study indicated that ZAP contributes to the decline of autonomic nervous system (ANS) function, especially parasympathetic components. The patients with ZAP lost parasympathetic advantage and had a worse ANS during the night.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/brb3.3489","type":"journal-article","created":{"date-parts":[[2024,4,30]],"date-time":"2024-04-30T22:44:50Z","timestamp":1714517090000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Circadian changes of autonomic function in patients with zoster\u2010associated pain: A heart rate variability analysis"],"prefix":"10.1002","volume":"14","author":[{"given":"Peng","family":"Mao","sequence":"first","affiliation":[{"name":"Department of Pain Medicine China\u2010Japan Friendship Hospital  Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5717-3733","authenticated-orcid":false,"given":"Hui\u2010Min","family":"Hu","sequence":"additional","affiliation":[{"name":"Graduate School of Beijing University of Chinese 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