{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T14:46:05Z","timestamp":1778856365970,"version":"3.51.4"},"reference-count":53,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2024,7,2]],"date-time":"2024-07-02T00:00:00Z","timestamp":1719878400000},"content-version":"vor","delay-in-days":1,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Brain and Behavior"],"published-print":{"date-parts":[[2024,7]]},"abstract":"<jats:sec>\n                    <jats:title>Background\/objectives<\/jats:title>\n                    <jats:p>Stroke damage to the primary visual cortex induces large, homonymous visual field defects that impair daily living. Here, we asked if vision\u2010related quality of life (VR\u2010QoL) is impacted by time since stroke.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Subjects\/methods<\/jats:title>\n                    <jats:p>We conducted a retrospective meta\u2010analysis of 95 occipital stroke patients (female\/male\u00a0=\u00a026\/69, 27\u201378 years old, 0.5\u2013373.5 months poststroke) in whom VR\u2010QoL was estimated using the National Eye Institute Visual Functioning Questionnaire (NEI\u2010VFQ) and its 10\u2010item neuro\u2010ophthalmic supplement (Neuro10). Visual deficit severity was represented by the perimetric mean deviation (PMD) calculated from 24\u20102 Humphrey visual fields. Data were compared with published cohorts of visually intact controls. The relationship between VR\u2010QoL and time poststroke was assessed across participants, adjusting for deficit severity and age with a multiple linear regression analysis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Occipital stroke patients had significantly lower NEI\u2010VFQ and Neuro10 composite scores than controls. All subscale scores describing specific aspects of visual ability and functioning were impaired except for ocular pain and general health, which did not differ significantly from controls. Surprisingly, visual deficit severity was not correlated with either composite score, both of which increased with time poststroke, even when adjusting for PMD and age.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>VR\u2010QoL appears to improve with time postoccipital stroke, irrespective of visual deficit size or patient age at insult. This may reflect the natural development of compensatory strategies and lifestyle adjustments. Thus, future studies examining the impact of rehabilitation on daily living in this patient population should consider the possibility that their VR\u2010QoL may change gradually over time, even without therapeutic intervention.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/brb3.3582","type":"journal-article","created":{"date-parts":[[2024,7,3]],"date-time":"2024-07-03T00:41:37Z","timestamp":1719967297000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Vision\u2010related quality of life after unilateral occipital stroke"],"prefix":"10.1002","volume":"14","author":[{"given":"Neil","family":"Dogra","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, Flaum Eye Institute and Center for Visual Science University of Rochester Rochester New York 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L.","family":"Lam","sequence":"additional","affiliation":[{"name":"Bascom Palmer Eye Institute University of Miami Miami Florida USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Madhura","family":"Tamhankar","sequence":"additional","affiliation":[{"name":"Scheie Eye Institute University of Pennsylvania Philadelphia Pennsylvania USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Steven E.","family":"Feldon","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Flaum Eye Institute and Center for Visual Science University of Rochester Rochester New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Berkeley","family":"Fahrenthold","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Flaum Eye Institute and Center for Visual Science University of Rochester Rochester New York 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