{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,10]],"date-time":"2026-06-10T05:07:38Z","timestamp":1781068058986,"version":"3.54.1"},"reference-count":11,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2015,7,22]],"date-time":"2015-07-22T00:00:00Z","timestamp":1437523200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Authors' Institution"},{"DOI":"10.13039\/501100007687","name":"Swedish Society of Medicine","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100007687","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100008738","name":"Jeansson Foundations","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100008738","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Thureus Foundation"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Brain and Behavior"],"published-print":{"date-parts":[[2015,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>Recently, several epidemiological studies have demonstrated that epilepsy develops after approximately 10% of all cerebrovascular lesions. With an aging population, poststroke epilepsy is likely to be of increasing relevance to neurologists and more knowledge on the condition is needed. Patients with poststroke epilepsy are likely to differ from other epilepsy patient populations regarding age, side\u2010effect tolerability, comorbidities, and life expectancy, all of which are important aspects when counselling newly diagnosed patients to make informed treatment decisions.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>We have here performed a nested case\u2013control study on 36 patients with poststroke epilepsy and 55 controls that suffered stroke but did not develop epilepsy. The average follow\u2010up time was between 3 and 4\u00a0years.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In our material, two\u2010thirds of patients achieved seizure freedom and 25% experienced a prolonged seizure (status epilepticus) during the follow\u2010up period. Cases consumed more health care following their stroke, but did not suffer more traumatic injuries. Interestingly, the mortality among cases and controls did not differ significantly. This observation needs to be confirmed in larger prospective studies, but indicate that poststroke epilepsy might not infer additional mortality in this patient group with considerable comorbidities.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The observations presented can be of value in the counselling of patients, reducing the psychosocial impact of the diagnosis, and planning of future research on poststroke epilepsy.<\/jats:p><\/jats:sec>","DOI":"10.1002\/brb3.366","type":"journal-article","created":{"date-parts":[[2015,7,22]],"date-time":"2015-07-22T05:40:03Z","timestamp":1437543603000},"source":"Crossref","is-referenced-by-count":17,"title":["Clinical course of poststroke epilepsy: a retrospective nested case\u2013control study"],"prefix":"10.1002","volume":"5","author":[{"given":"Johan","family":"Zelano","sequence":"first","affiliation":[{"name":"Department of Neuroscience Uppsala University 751 85 Uppsala Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rebecca Gertz","family":"Lundberg","sequence":"additional","affiliation":[{"name":"Department of Neuroscience Uppsala University 751 85 Uppsala Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leopold","family":"Baars","sequence":"additional","affiliation":[{"name":"Department of Neuroscience Uppsala University 751 85 Uppsala Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emelie","family":"Hedeg\u00e4rd","sequence":"additional","affiliation":[{"name":"Department of Neuroscience Uppsala University 751 85 Uppsala Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eva","family":"Kumlien","sequence":"additional","affiliation":[{"name":"Department of Neuroscience Uppsala University 751 85 Uppsala Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2015,7,22]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0055498"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000436619.25532.f3"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/epi.12550"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.111.000220"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.114.004686"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.0000204041.13466.4c"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/ane.12070"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eplepsyres.2013.08.009"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1528-1167.2007.01128.x"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/0140-6736(90)92959-L"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-010-5520-9"}],"container-title":["Brain and Behavior"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fbrb3.366","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/brb3.366","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/brb3.366","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/brb3.366","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,6]],"date-time":"2023-10-06T20:19:07Z","timestamp":1696623547000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/brb3.366"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,7,22]]},"references-count":11,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2015,9]]}},"alternative-id":["10.1002\/brb3.366"],"URL":"https:\/\/doi.org\/10.1002\/brb3.366","archive":["Portico"],"relation":{},"ISSN":["2162-3279","2162-3279"],"issn-type":[{"value":"2162-3279","type":"print"},{"value":"2162-3279","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,7,22]]},"article-number":"e00366"}}