{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T21:20:08Z","timestamp":1791580808183,"version":"4.3.4"},"reference-count":21,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2016,10,11]],"date-time":"2016-10-11T00:00:00Z","timestamp":1476144000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Research Committee for CNS Degenerative Diseases from the Ministry of Health, Labor, and Welfare of Japan"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Brain and Behavior"],"published-print":{"date-parts":[[2016,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Progressive supranuclear palsy (<jats:styled-content style=\"fixed-case\">PSP<\/jats:styled-content>) is a neurodegenerative disorder that is sometimes confused with Parkinson's disease, multiple system atrophy, and other disorders. The typical clinical features are categorized as Richardson's syndrome (<jats:styled-content style=\"fixed-case\">RS<\/jats:styled-content>), but other clinical subtypes include <jats:styled-content style=\"fixed-case\">PSP<\/jats:styled-content>\u2010parkinsonism (<jats:styled-content style=\"fixed-case\">PSP<\/jats:styled-content>\u2010P) and <jats:styled-content style=\"fixed-case\">PSP<\/jats:styled-content>\u2010pure akinesia with gait freezing (<jats:styled-content style=\"fixed-case\">PSP<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">PAGF<\/jats:styled-content>). In this study, we determined the prevalence of <jats:styled-content style=\"fixed-case\">PSP<\/jats:styled-content> in a Japanese rural area compared to our previous 1999 report.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We collected data in Yonago City from 2009 to 2014 using a service\u2010based study of <jats:styled-content style=\"fixed-case\">PSP<\/jats:styled-content>. We collected case history data from <jats:styled-content style=\"fixed-case\">PSP<\/jats:styled-content> patients in the area from our hospital. The crude prevalence and 95% confidence interval (<jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>) were calculated using the population demographics on the prevalence day of 1 October 2010. Age\u2010 and sex\u2010adjusted prevalence was calculated by direct standardization to the population demographics in Yonago City on the prevalence day of 1 April 1999.<\/jats:p><\/jats:sec><jats:sec><jats:title>Material and Results<\/jats:title><jats:p>We identified 25 patients: 16 with probable <jats:styled-content style=\"fixed-case\">RS<\/jats:styled-content>, 4 with possible <jats:styled-content style=\"fixed-case\">RS<\/jats:styled-content>, 3 with clinical <jats:styled-content style=\"fixed-case\">PSP<\/jats:styled-content>\u2010P, and 2 with clinical <jats:styled-content style=\"fixed-case\">PSP<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">PAGF<\/jats:styled-content>. The prevalence per 100,000 was 17.90 (male\u00a0=\u00a018.05; female\u00a0=\u00a017.76). The prevalence of <jats:styled-content style=\"fixed-case\">PSP<\/jats:styled-content> in Yonago in 2010 increased compared to the measurements from 1999.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The prevalence of <jats:styled-content style=\"fixed-case\">PSP<\/jats:styled-content> in Japan increased from 1999 to 2010.<\/jats:p><\/jats:sec>","DOI":"10.1002\/brb3.557","type":"journal-article","created":{"date-parts":[[2016,10,13]],"date-time":"2016-10-13T15:16:29Z","timestamp":1476371789000},"source":"Crossref","is-referenced-by-count":56,"title":["Prevalence of progressive supranuclear palsy in Yonago: change throughout a decade"],"prefix":"10.1002","volume":"6","author":[{"given":"Hiroshi","family":"Takigawa","sequence":"first","affiliation":[{"name":"Division of Neurology Department of Brain and Neurosciences Faculty of Medicine Tottori University  Tottori 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